| DDR & Partners (SPV1) Limited | Construction | 2025 |
| DDR & Partners Limited | Real estate | 2025 |
| DE Veer Prescient (NO1) Limited | Real estate | 2020 |
| Deans Computer Services Limited | Information & communication | 1982 |
| Deans Computer Services Trustees Limited | Administrative & support | 2024 |
| Deathriders Ltd | Arts & recreation | 2019 |
| DEC (York) Ltd | Information & communication | 2019 |
| Declan Campbell Electrical Services Ltd | Construction | 2023 |
| Decon Solutions Limited | Professional & scientific | 2008 |
| Deem Limited | Real estate | 1978 |
| Deem Property Management Limited | Households | 2022 |
| Deep Blue Networks Limited | Information & communication | 2004 |
| Deerstone Developments Limited | Wholesale & retail | 2005 |
| Define Holdings Ltd | Manufacturing | 2026 |
| Delacey Holdings Limited | Financial services | 2020 |
| Delacey Investment Holdings Limited | Financial services | 2024 |
| Delacey Services Group Limited | Financial services | 2024 |
| Delacey Technology Group Limited | Financial services | 2024 |
| Delcom Services Ltd | Professional & scientific | 2022 |
| Delta Filter Services Limited | Manufacturing | 2004 |
| Deltalord Ltd | Real estate | 1976 |
| Demi Hurley Ltd | Hospitality | 2025 |
| Denson Automotive Limited | Manufacturing | 2019 |
| Denson PK Limited | Wholesale & retail | 2019 |
| Dentistry@ Limited | Health & social care | 2008 |
| Dependall Ltd | Wholesale & retail | 2020 |
| Depth Collective Limited | Information & communication | 2022 |
| Derwent Group Limited | Real estate | 2021 |
| Design House Interiors UK Limited | Wholesale & retail | 2024 |
| Design. (by Jacob) Ltd | Professional & scientific | 2014 |
| Destiny Rich Ltd | Extraterritorial | 2024 |
| Devcaregroup Limited | Real estate | 2020 |
| Dezap Limited | Wholesale & retail | 2017 |
| Dezipp Ltd. | Hospitality | 2024 |
| DG & TC Ltd | Administrative & support | 2024 |
| DGL Motorsport Limited | Transport & logistics | 2019 |
| Dgmhhh Limited | Wholesale & retail | 2022 |
| Diamond Diesels (UK) Limited | Wholesale & retail | 2001 |
| Diamond Diesels Enterprises Limited | Professional & scientific | 2013 |
| Diamond Diesels Investments Limited | Professional & scientific | 2009 |
| Diamond Holdings ( West Yorkshire ) Ltd | Real estate | 2026 |
| Dick.Co Limited | Wholesale & retail | 2016 |
| Dickinson Planning Limited | Professional & scientific | 2020 |
| Dickinson Wealth Management Limited | Administrative & support | 2010 |
| Dietpen Consultants Ltd | Health & social care | 2025 |
| Digitak Consulting Limited | Information & communication | 2023 |
| Digital Health CMO Ltd | Financial services | 2024 |
| Digital Mailroom Ltd | Information & communication | 2010 |
| Digital Symphony Limited | Information & communication | 2017 |
| Digital Threat Management Limited | Information & communication | 2019 |
| Dimples Oral Care Ltd | Manufacturing | 2022 |
| Dinsdale & Co Limited | Other services | 2018 |
| Directbrick&Stone Ltd | Manufacturing | 2022 |
| Discount Feeds Ltd | Other services | 2018 |
| Division X Creative Limited | Manufacturing | 2020 |
| Dizzy Heights Solutions Limited | Professional & scientific | 2016 |
| DK Electric Services Ltd | Construction | 2023 |
| DK Sales Solution Limited | Professional & scientific | 2014 |
| Dlhkh Media Ltd | Professional & scientific | 2010 |
| DMB Collection Ltd | Wholesale & retail | 2019 |
| Dmypay Limited | Administrative & support | 2025 |
| DNA Property Sourcing Limited | Real estate | 2024 |
| DNM Engineering Ltd | Manufacturing | 2018 |
| DO (UK) Holdings Ltd | Financial services | 2023 |
| Dobson Property Ventures Limited | Real estate | 2025 |
| Dodson Inspection Services Ltd | Professional & scientific | 2025 |
| Domi Brands Limited | Professional & scientific | 2026 |
| Doodle & Scarf Ltd | Construction | 2026 |
| Doodle IP Limited | Information & communication | 2015 |
| Dose Altrincham Limited | Wholesale & retail | 2024 |
| Douglas-Roberts Holdings Ltd | Real estate | 2024 |
| Douthwaite & Co Limited | Wholesale & retail | 2009 |
| DPE Beta Properties Limited | Real estate | 2021 |
| DR J M Bamford Limited | Health & social care | 2014 |
| DR Sharon Lewis Ltd | Health & social care | 2022 |
| Dragonfly Grounds & Tree Care Ltd | Extraterritorial | 2012 |
| Dreamgenies Limited | Arts & recreation | 1999 |
| Dressed Ltd | Wholesale & retail | 2023 |
| DRJ Accountants Holdings Ltd | Financial services | 2023 |
| Drouth Ltd | Hospitality | 2017 |
| Drummonds Kitchens & Bedrooms Limited | Wholesale & retail | 2003 |
| DS Medical Services Limited | Health & social care | 2017 |
| DS Medical Solutions Limited | Information & communication | 2017 |
| DSB Polymers Limited | Professional & scientific | 2024 |
| DSP Sea Limited | Information & communication | 2026 |
| DSW Property Group Ltd | Real estate | 2025 |
| DTC Ltd | Administrative & support | 2020 |
| Duck Dating Ltd | Professional & scientific | 2026 |
| Duffield Court (Wetherby) Management Company Ltd | Households | 2014 |
| Dune Computers Limited | Information & communication | 1991 |
| Dunemill Limited | Real estate | 1987 |
| DW (Couriers York) Ltd | Transport & logistics | 2020 |
| DW Squared Limited | Real estate | 2016 |
| DWB Wealth Consultancy (Wetherby) LLP | | 2013 |
| DWB Wealth Consultancy Limited | Professional & scientific | 2024 |
| E & T Hogg Limited | Hospitality | 2020 |
| E (GAS and Electricity) Limited | Energy | 2013 |
| E L J Wealth Management Ltd | Financial services | 2014 |
| E&B Holdings (2026) Ltd | Financial services | 2026 |
| Ease MAN Sourcing Ltd | Real estate | 2021 |