| Solveon Limited | Health & social care | 2023 |
| Somax Limited | Education | 2004 |
| Somerset Aviation Services Ltd | Transport & logistics | 2020 |
| Somerset Beds & Mattresses Ltd | Wholesale & retail | 2009 |
| Somerset Bespoke Limited | Manufacturing | 2011 |
| Somerset Chilli Garden Ltd | Agriculture & fishing | 2020 |
| Somerset Construction Limited | Extraterritorial | 2012 |
| Somerset Court Cottages Limited | Hospitality | 2003 |
| Somerset Drives and Patios Ltd | Administrative & support | 2021 |
| Somerset Freight Solutions Ltd | Wholesale & retail | 2018 |
| Somerset Hair & Beauty Supplies Limited | Administrative & support | 2012 |
| Somerset Installations Limited | Construction | 2015 |
| Somerset Road Sweepers Ltd | Transport & logistics | 2020 |
| Somerset Security & Electrical Solutions Ltd | Construction | 2017 |
| Somerset Website Designs Ltd | Information & communication | 2025 |
| Somerset Wood Recycling C.I.C. | Manufacturing | 2006 |
| Somertec Ltd | Information & communication | 2005 |
| Soteria Treats Limited | Manufacturing | 2025 |
| Soto Polo Ponies Limited | Agriculture & fishing | 2020 |
| Soulwise Academy Limited | Health & social care | 2016 |
| Source Electrical Services Limited | Manufacturing | 2019 |
| South W Mobile Limited | Wholesale & retail | 2026 |
| South West Building Compliance Ltd | Construction | 2025 |
| South West Flat Ltd | Other services | 2024 |
| South West Global Communications Limited | Professional & scientific | 2019 |
| South West Lighting and Electrical Limited | Wholesale & retail | 2012 |
| South West Memorabilia & Events Ltd | Wholesale & retail | 2019 |
| South West Sharks Allstar Cheerleading Ltd | Arts & recreation | 2025 |
| South West UK Heating Limited | Construction | 2014 |
| South West UK Plumbing Ltd | Construction | 2014 |
| South West Women's Health Ltd | Health & social care | 2021 |
| South Weston Electrical Wholesale Limited | Wholesale & retail | 2026 |
| Southern Conservatories Ltd | Construction | 1988 |
| Southern Industries Limited | Financial services | 2023 |
| Southern Motorhome Hire Ltd | Wholesale & retail | 2011 |
| Southernhay Mansions Management Limited | Households | 1989 |
| Southerton Podiatric Practice Ltd | Health & social care | 2016 |
| Southside Management Company Limited | Households | 1990 |
| Southside Mansions Management Limited | Households | 1989 |
| Southside WSM Limited | Households | 2019 |
| Southwest Chauffeur, Auto and Driver Services Ltd | Transport & logistics | 2015 |
| Southwest Electrical Services Limited | Construction | 2015 |
| Sovtec Ltd | Information & communication | 2013 |
| Sowden Air Solutions Ltd | Professional & scientific | 2019 |
| Spaces & Places Holdings Limited | Financial services | 2018 |
| Spaces & Places Properties Ltd | Real estate | 2012 |
| Spaces 365 Ltd | Households | 2025 |
| Spansec Security Ltd | Administrative & support | 2009 |
| Sparks Learning Limited | Education | 2023 |
| Special Delivery Services Limited | Transport & logistics | 2011 |
| Specialist Automotive Mechanical Services Ltd | Wholesale & retail | 2022 |
| Specialist Mobile Services Ltd | Wholesale & retail | 2019 |
| Spices Boyz Ltd | Hospitality | 2024 |
| Spicy Sweets Ltd | Hospitality | 2026 |
| Spire House Management Company (Weston-Super-Mare) Limited | Households | 1988 |
| SPL Properties (SW) Ltd | Real estate | 2020 |
| Split Air Conditioning and Heating Services Ltd | Energy | 2026 |
| Splitz Gymnastics Club Ltd | Arts & recreation | 2017 |
| Sponsormyteam Ltd | Information & communication | 2025 |
| Sporting Legends Limited | Arts & recreation | 2010 |
| Sportonova Limited | Extraterritorial | 2017 |
| Spotless Home Services Limited | Administrative & support | 2022 |
| Springbank Residents Association Limited | Households | 1990 |
| Springfield (Bath) Limited | Health & social care | 2009 |
| Springvale (Weatherproofing) Holdings Limited | Administrative & support | 1999 |
| Sprosen Commercial Ltd | Real estate | 2014 |
| Sprout SW CIC | Hospitality | 2023 |
| SPT Haulage Ltd | Transport & logistics | 2026 |
| Squeaky-Clean-Wsm Ltd | Real estate | 2022 |
| SRC Engineering Ltd | Professional & scientific | 2023 |
| Srct Consultants Ltd | Real estate | 2010 |
| SRR Property Management Ltd | Real estate | 2022 |
| Ssbamd Ltd | Health & social care | 2022 |
| ST Austins (Sand Bay) Management Company Limited | Hospitality | 1989 |
| ST Congar Group Limited | Extraterritorial | 2021 |
| ST Congar Provincial (Chigwell) Limited | Real estate | 2015 |
| ST Congar Provincial Limited | Extraterritorial | 2015 |
| ST Hill Leadership & Development Ltd | Professional & scientific | 2025 |
| ST Marks PRE School (Worle) Limited | Education | 2017 |
| ST People Focus Ltd | Professional & scientific | 2018 |
| ST Peters Court Management (WSM) Company Limited | Households | 2000 |
| ST Reatham Housing Limited | Real estate | 2018 |
| ST Saviours Court Management Company Limited | Households | 2015 |
| ST. Bridges Court Management Company (Kewstoke) Limited | Households | 2015 |
| ST. Congar Asset Management Limited | Real estate | 2008 |
| ST. Congar Homes Limited | Real estate | 2013 |
| ST. Congar Land Ltd | Real estate | 2009 |
| ST. Congar Limited | Extraterritorial | 2023 |
| ST. David Recruitment Services Ltd | Administrative & support | 2002 |
| ST. Leonards (W-S-M) Management Limited | Households | 1991 |
| ST. Martins Court (Worle) Management Limited | Households | 1982 |
| Staart Global Ltd | Wholesale & retail | 2016 |
| Stable View Developments Ltd | Construction | 2022 |
| Stage Door Property Group Limited | Real estate | 2026 |
| Stagg Tech Limited | Information & communication | 2013 |
| Stand Future Ltd | Wholesale & retail | 2023 |
| Stand Referral Marketing Ltd | Other services | 2018 |
| Standout Designs Ltd | Manufacturing | 2020 |
| Staplegrove Welding Ltd | Manufacturing | 2012 |
| Stars Childcare Limited | Education | 2022 |