| Sports Turf Research Institute(The) | Professional & scientific | 1951 |
| Springfield Garage (Keighley) Limited | Wholesale & retail | 1966 |
| Springwood Place Management Company Limited | Households | 2005 |
| Spruce Engineering Company Limited | Manufacturing | 1999 |
| Square Feet Properties Ltd | Real estate | 2004 |
| Sreechandu Properties Ltd | Real estate | 2022 |
| SRI Krishna Udupi Limited | Health & social care | 2020 |
| ST Hughes Lodge Management Company Limited | Real estate | 2006 |
| Stafflex Limited | Administrative & support | 1999 |
| Staffordshire Tableware Limited | Manufacturing | 1990 |
| Stag Open Systems Limited | | 1991 |
| Stainless Engineering Ltd | Manufacturing | 2006 |
| Standard Patent Glazing Company Limited(The) | Manufacturing | 1904 |
| Stanrod Limited | Real estate | 1999 |
| Star East Yorks Ltd | Hospitality | 2017 |
| Starling Properties Limited | Real estate | 2003 |
| Steadfast Insurance Brokers Limited | Financial services | 1961 |
| Steelace Limited | Manufacturing | 1991 |
| Stemic Chemicals Limited | | 1979 |
| Stephen Beck Ltd | Construction | 2002 |
| Stephen Crabtree Limited | Construction | 2002 |
| Stercap Limited | Wholesale & retail | 2001 |
| Sterlingingwave Ltd | Wholesale & retail | 2025 |
| Steve Holbrook Ltd | Other services | 2002 |
| Stewart James Limited | Information & communication | 1997 |
| Stocking Affair Limited | Wholesale & retail | 1983 |
| Stocks Sewing Machines Limited | Manufacturing | 1999 |
| Stockton Travel Limited | Administrative & support | 1989 |
| Stoelzle Flaconnage Limited | Manufacturing | 1994 |
| Stonegate Dental Limited | Health & social care | 2007 |
| Stonehouse Group Employees Limited | Administrative & support | 2021 |
| Stoneleigh Electrical Contractors Limited | Construction | 1998 |
| Stoneywood Limited | Wholesale & retail | 2007 |
| Stop and Shop Newsagents Limited | Wholesale & retail | 2003 |
| Stott Benham Limited | Manufacturing | 1996 |
| Straightline Surveys Limited | Professional & scientific | 2004 |
| Straightliners Limited | Arts & recreation | 2003 |
| Stranathro Properties Limited | Real estate | 1978 |
| Strandhall Management Ltd | Financial services | 2009 |
| Strategic Change Solutions Limited | Professional & scientific | 2004 |
| Streamline Developments Limited | Real estate | 2002 |
| Stretch Audio Limited | Manufacturing | 2007 |
| Stuart Tordoff Limited | Wholesale & retail | 1992 |
| Studio 44 Kitchens Limited | Transport & logistics | 1988 |
| Sugden Audio Limited | Extraterritorial | 2001 |
| Suisoft Limited | Information & communication | 2007 |
| Sukdb Pension Trustees Limited | Financial services | 1972 |
| Sulzer (UK) Holdings Limited | Administrative & support | 1997 |
| Sulzer Chemtech (UK) Limited | Manufacturing | 1994 |
| Sulzer Pumps (UK) Limited | Manufacturing | 1986 |
| Summit Accountancy Services Limited | Professional & scientific | 2008 |
| Sumtimwave Solutions Ltd | Wholesale & retail | 2025 |
| Sunridge JDM I Limited | Financial services | 2021 |
| Sunridge JDM II Limited | Financial services | 2021 |
| Suntrim Limited | Wholesale & retail | 1984 |
| Supreme Labelling Limited | Wholesale & retail | 1999 |
| Sure Technical Limited | Construction | 1997 |
| Surf-Time Limited | Other services | 2004 |
| Sussex County Homes Limited | Construction | 1988 |
| Swanpride Limited | Wholesale & retail | 1997 |
| Sweeney Todds (Leeds) Limited | Other services | 2007 |
| Sweet Centre Limited | Hospitality | 1998 |
| Sweet Centre Restaurant Limited | Hospitality | 1998 |
| Sweet Consulting Services Ltd | Information & communication | 2007 |
| Sweet Garden Limited | Information & communication | 2008 |
| Sweetheat Technology Limited | Manufacturing | 2002 |
| SX Realisations Limited | Water & waste | 1926 |
| SYM Management Limited | Real estate | 2003 |
| Symphony Properties Limited | Wholesale & retail | 2007 |
| Syrol Limited | Wholesale & retail | 2006 |
| T Backhouse & SON Limited | Manufacturing | 2007 |
| T Harding Light Haulage Limited | Transport & logistics | 2004 |
| T.S. Booker & SON (Manufacturing) Limited | Manufacturing | 1996 |
| T.W. Mercedes Properties Limited | Real estate | 2004 |
| Taafe Limited | Wholesale & retail | 2025 |
| Tanayah Ltd | Wholesale & retail | 2020 |
| Taylor Studwelding Systems Limited | Manufacturing | 1984 |
| Taylormade Coaching & Events Ltd | Arts & recreation | 2024 |
| Taylorshaw Valves Limited | Manufacturing | 2007 |
| TCH (Leeds) Limited | Real estate | 2009 |
| TDW Services Limited | Construction | 1983 |
| Tech Services (Corporate) Limited | Construction | 2004 |
| Techmotion Limited | Manufacturing | 2008 |
| Techno Constructions Limited | Construction | 1957 |
| Techno Holdings Limited | Construction | 1969 |
| Telinject Services UK Limited | Manufacturing | 2003 |
| Textile Innovations Limited | Wholesale & retail | 2007 |
| Thackers (Commercial) Limited | Manufacturing | 1997 |
| Thackers Commercial (Holdings) Limited | Professional & scientific | 2001 |
| THE Accounting Company (Leeds) Limited | Professional & scientific | 2005 |
| THE Avenue (Crossgates) Leeds Limited | Households | 1998 |
| THE Bradford Bulls Foundation | Education | 2004 |
| THE Bright Side of the Road Limited | Real estate | 1987 |
| THE Cloth House (Huddersfield) England Limited | Professional & scientific | 2006 |
| THE Company Called Beyond Limited | Professional & scientific | 2003 |
| THE Courthouse Project (Otley) Limited | Hospitality | 2001 |
| THE Cross Gates & District Recreation Hall Limited | Hospitality | 1995 |
| THE Cutting Booth Limited | Other services | 2002 |
| THE Ethical Jeweller Ltd | Wholesale & retail | 2003 |
| THE Eurotrade Commission Limited | Extraterritorial | 1998 |