| Richards Scrap Metals Limited | Extraterritorial | 1973 |
| Richmond Property & Development Limited | Construction | 2006 |
| Ricor Trade Holdings Limited | Professional & scientific | 2006 |
| Rider Levett Bucknall Limited | Extraterritorial | 2005 |
| Ridgewood Homes Holdings Limited | Professional & scientific | 2006 |
| Right UP Your Street Ltd | Real estate | 2000 |
| Rileys Opticians Limited | Wholesale & retail | 2006 |
| Rillisi Ltd | Wholesale & retail | 2023 |
| RIO Landscapes Limited | Professional & scientific | 2007 |
| Rising Sun Group Ltd | Wholesale & retail | 2023 |
| Rithma Labs Ltd | Information & communication | 2025 |
| Riva Revival (U.K.) Limited | Administrative & support | 1998 |
| RJU Limited | Hospitality | 2006 |
| RKA Solutions Limited | Manufacturing | 2007 |
| RKT (UK) Limited | Education | 1999 |
| RMD Kwikform Limited | Administrative & support | 1935 |
| RME (UK) Limited | Arts & recreation | 2006 |
| Rmsk Care Ltd | Health & social care | 2024 |
| RNT Property Managment Limited | Other services | 2007 |
| Roadlink Europe Limited | Professional & scientific | 1990 |
| Roadlink Holdings Limited | Professional & scientific | 2006 |
| Roadlink International Limited | Wholesale & retail | 1982 |
| ROB Guest Electrical Services Limited | Energy | 2006 |
| Robert Lickley Consultancy and Contractors Limited | Extraterritorial | 1972 |
| Roberts Franklin & Co. Limited | Professional & scientific | 2006 |
| Robin Arnold Technologies Limited | Manufacturing | 1998 |
| Robinson Brothers (Ryders Green) Limited | Financial services | 1894 |
| Robinson Employee Benefit Trust Limited | Professional & scientific | 1990 |
| Robinson Employee Share Trust Limited | Financial services | 1988 |
| Rocker Way Transport Ltd | Transport & logistics | 2024 |
| Rocore (UK) Limited | Real estate | 2002 |
| Rodney Ashford Associates Ltd. | Professional & scientific | 2007 |
| Roger Francis Limited | Professional & scientific | 2006 |
| Roman Bathroom & Tile Centre Limited | Wholesale & retail | 1998 |
| Ronnie Electric Co., Limited | Manufacturing | 2023 |
| Roots Optical Limited | Health & social care | 2006 |
| Roppos Development Co., Ltd | Wholesale & retail | 2024 |
| Rosebeech Enterprises Limited | Professional & scientific | 2005 |
| Roseshine Limited | Wholesale & retail | 2002 |
| Roseville Dental Ltd | Health & social care | 2025 |
| Roseville Voice & Data Cabling Limited | Construction | 2008 |
| Rothkopf Information Limited | Administrative & support | 2005 |
| Rothwells Limited | Real estate | 1999 |
| Round Oak Electrical Limited | Construction | 1983 |
| Rounded Labs Ltd | Information & communication | 2007 |
| Roundtable Consultancy Limited | Professional & scientific | 2006 |
| Roway Metals Limited | Manufacturing | 1947 |
| Rowell Installation Limited | Manufacturing | 2003 |
| Royal Birmingham Society of Artists.(The) | Arts & recreation | 1912 |
| RS Digital Solutions Ltd | Information & communication | 2014 |
| RSG IT Services Ltd | Information & communication | 2017 |
| RSS Edge Shoes Limited | Wholesale & retail | 1998 |
| RSW Software Ltd | Information & communication | 2006 |
| Ruberoid (Realisations) Limited | Professional & scientific | 1935 |
| Rudds Cleaning Services Limited | Administrative & support | 2024 |
| Rufford Makers & Co Limited | Administrative & support | 1994 |
| Ruitian Trading Co., Ltd | Wholesale & retail | 2023 |
| Ruiyi Trade Limited | Wholesale & retail | 2023 |
| Russell's Waste Management Limited | Water & waste | 2007 |
| Rusworld Properties Ltd | Real estate | 2005 |
| Ruth Williams Multimedia Limited | Information & communication | 2001 |
| Ruxton Independent Estate Agents & Valuers LLP | | 2004 |
| Rxhhd Ltd | Wholesale & retail | 2025 |
| Ryan Accountancy Limited | Professional & scientific | 2006 |
| Ryan Flooring (Midlands) Ltd | Construction | 2009 |
| S & a Electrical Repair Services Limited | Construction | 2000 |
| S & B Constructions & Maintenance Limited | Construction | 2006 |
| S & D (Non-Ferrous Stockholders) Limited | Wholesale & retail | 1974 |
| S & F Tax Returns Ltd | Professional & scientific | 2009 |
| S & J Pritchard Landscapes Limited | Administrative & support | 2007 |
| S & S Domestic Appliances Limited | Manufacturing | 2003 |
| S Cadwallader and Sons Limited | Transport & logistics | 2006 |
| S Darby Building Contractors Ltd | Construction | 2005 |
| S Elliott Partnership Limited | Professional & scientific | 2004 |
| S J Limited | Health & social care | 2002 |
| S K Fashions (Midlands) Limited | Wholesale & retail | 2006 |
| S K Smith Building Services Limited | Construction | 2008 |
| S M Mobile Limited | Wholesale & retail | 2002 |
| S M Properties (21) Limited | Professional & scientific | 1994 |
| S Wallace Developments Limited | Construction | 2007 |
| S. Parton (Construction) Limited | Construction | 2000 |
| S. S. Sidhu (Gases) Limited | Extraterritorial | 1992 |
| S. Turner & Associates Limited | Financial services | 1985 |
| S. W. Foley Limited | Construction | 2006 |
| S.A.M.M. Services (Midlands) Limited | Administrative & support | 1985 |
| S.F. Harrison Roofing Limited | Construction | 1987 |
| S.I.S. Group Limited | Professional & scientific | 1985 |
| S.J. Griffin & Sons Ltd | Construction | 2002 |
| S.Millard Plastering Limited | Construction | 2006 |
| Saasoft Ltd | Information & communication | 2005 |
| Sabre Event Merchandise Limited | Wholesale & retail | 2003 |
| Safe Eco Ltd | Construction | 2025 |
| Safe Real Estates Ltd | Real estate | 2024 |
| Safe Services & Solutions Ltd | Administrative & support | 2024 |
| Safe Transport Limited | | 1982 |
| Safeclean (West Midlands) Limited | Other services | 2000 |
| Sahara Construction Ltd | Construction | 2020 |
| Sahil Project | Health & social care | 2004 |
| Sahistores Ltd | Wholesale & retail | 2021 |
| Saigon Studio Nails Ltd | Other services | 2019 |