| English Romance Limited | Administrative & support | 2004 |
| Enivel Electric Co. , Ltd | Manufacturing | 2023 |
| Ensco Engineering Limited | Professional & scientific | 2000 |
| Enterkey Training Limited | Education | 2006 |
| Enterprise Inns Holding Company Limited | Professional & scientific | 2004 |
| Entertainment Finance Investment Limited | Administrative & support | 2005 |
| Enville Estate Management Limited | Extraterritorial | 2000 |
| EOM Consulting Limited | Professional & scientific | 2008 |
| EPS Investments Ltd. | Real estate | 1982 |
| ERA Automation Limited | Professional & scientific | 1999 |
| Erabee Smart Home Co., Limited | Manufacturing | 2023 |
| Eranthemum Ltd | Construction | 2023 |
| Eremophila Ltd | Construction | 2023 |
| Ernest W.Lucas & Co.Limited | Wholesale & retail | 1943 |
| ESP Automotive Limited | Wholesale & retail | 1999 |
| Esther-Zen Care Services Ltd | Public administration | 2023 |
| Estil Limited | Manufacturing | 1983 |
| EU Networks Limited | Administrative & support | 2004 |
| Euphoria Hotels Ltd | Hospitality | 2007 |
| Euro - Spec Telecom Limited | Transport & logistics | 2002 |
| Euro BAU Limited | Professional & scientific | 2001 |
| Euro Claddings Limited | Wholesale & retail | 1974 |
| Euro Profile International Systems Limited | Manufacturing | 1992 |
| Eurohire Limited | Administrative & support | 1988 |
| Eurohire Vehicle Rentals (Oldbury) Limited | Administrative & support | 1979 |
| European Heathyards Ltd | Manufacturing | 2021 |
| European Law Ltd | Other services | 2020 |
| European Window Systems Limited | Construction | 2006 |
| Eurox (UK) Limited | Extraterritorial | 1989 |
| Eutagro - Dairy - Limited | Administrative & support | 2005 |
| Eutectic Alloy Castings (Wolverhampton) Limited | Manufacturing | 1978 |
| Evaldas Luckauskas Ltd | Wholesale & retail | 2024 |
| Evawhite Windows Limited | Construction | 2004 |
| Events With the Edge Limited | Real estate | 1952 |
| Eversfield Preparatory School Trust Limited | Education | 1958 |
| Evie Clark Limited | Other services | 2003 |
| EVO Music Publishing Ltd | Administrative & support | 2020 |
| EVO Music Management Ltd | Administrative & support | 2020 |
| EVO Touring Ltd | Administrative & support | 2020 |
| Evojoy Technology Co., Ltd. | Wholesale & retail | 2023 |
| Excalibur Property Services Limited | Real estate | 2015 |
| Excel Heat Furnaces Limited | Professional & scientific | 2006 |
| Excel Paving Ltd | Wholesale & retail | 2003 |
| Excelsior Systems Limited | Information & communication | 1999 |
| Executive Projects Limited | Real estate | 2002 |
| Executive Training and Consultancy Limited | Professional & scientific | 2007 |
| Expert Avenue Limited | Information & communication | 2011 |
| Expert Microbiologist Ltd | Health & social care | 2024 |
| Explore Kitchen Food Limited | Wholesale & retail | 2023 |
| Express Packaging Limited | Extraterritorial | 1982 |
| Extensions ETC Limited | Professional & scientific | 2000 |
| Extraskills Limited | Professional & scientific | 2007 |
| Eydens Limited | Administrative & support | 2000 |
| EYE Internet Limited | Information & communication | 1994 |
| Eye-Docs Limited | Health & social care | 2002 |
| Eyesite Limited | Wholesale & retail | 1997 |
| F & J Exports Limited | Wholesale & retail | 1979 |
| F. Martin and SON Limited | Manufacturing | 1977 |
| F.C. Sports Limited | Wholesale & retail | 2005 |
| F.S.W Ltd | Transport & logistics | 2005 |
| F.W. Pine Limited | Water & waste | 1994 |
| Facade Developments Limited | Construction | 1992 |
| Face to Face Marketing Limited | Professional & scientific | 2026 |
| Faintree Investments Ltd | Real estate | 1993 |
| Falcon Carded Products Limited | | 1987 |
| Fancy Silk Store (Birmingham) Limited | Wholesale & retail | 1973 |
| Farida Investment Co., Ltd | Wholesale & retail | 2023 |
| Fast Fit Plus Limited | Wholesale & retail | 2004 |
| Fast Track Site Services Limited | Wholesale & retail | 1999 |
| Fastenright Limited | Wholesale & retail | 1983 |
| FBR Investments Limited | Construction | 2002 |
| FBS Intelligent Engineering (IE) Ltd | Construction | 2006 |
| Fellows and Ramsay Limited | Manufacturing | 2004 |
| Fellows, Morton & Clayton Limited | Transport & logistics | 1986 |
| Feminine Clothing Limited | Manufacturing | 1993 |
| Ferdotti Motor Services Limited | Wholesale & retail | 2005 |
| Feridax (1957) Limited | Manufacturing | 1994 |
| Feridax Group Limited | Wholesale & retail | 2007 |
| Fibreseal Limited | Manufacturing | 2001 |
| Fieldhouse Consulting Limited | Administrative & support | 2006 |
| Fieldings Auctioneers Limited | Professional & scientific | 2001 |
| Financial Accounting Solutions Limited | Professional & scientific | 2004 |
| Find Your Aces Ltd. | Other services | 2012 |
| Fineline Paving (Midlands) Ltd | Construction | 2012 |
| Finger Post Shutters and Doors Limited | Manufacturing | 1999 |
| Finnegan Brothers Limited | Construction | 2001 |
| Finsbridge Investments Ltd | Transport & logistics | 2021 |
| Fintax UK Limited | Professional & scientific | 2003 |
| First Contact Technical Services Limited | Manufacturing | 2002 |
| First Future Management Limited | Professional & scientific | 2001 |
| Fisherman's Friend (B'Ham) Limited | Wholesale & retail | 2002 |
| Fiton Limited | Administrative & support | 2002 |
| Fittingly Ltd | Manufacturing | 2018 |
| Fixmy Appliance Solutions Ltd | Wholesale & retail | 2006 |
| Flairprint Limited | Wholesale & retail | 1972 |
| Flamesurge Limited | Manufacturing | 1988 |
| FLD Property Ltd | Real estate | 2022 |
| Fleet Hire Holdings Limited | Administrative & support | 2007 |
| Fletchers Foods Limited | Professional & scientific | 2002 |
| Flex Car Hire Ltd | Administrative & support | 2025 |