| Southbourne Electrical Services Limited | Construction | 2001 |
| Southern Vulcanizing Engineering Limited | Manufacturing | 1997 |
| Southern Vulcanizing Limited | Manufacturing | 1993 |
| Southern Vulcanizing Partnership Limited | Manufacturing | 2015 |
| Southlands Community Café Ltd | Hospitality | 2025 |
| Southrise International Ltd | Wholesale & retail | 2025 |
| Southwest Buildups Ltd | Real estate | 2022 |
| SP - Sandhu & Patwalia Builders Ltd | Construction | 2022 |
| SP Simha Consulting Ltd | Information & communication | 2024 |
| Space Education and Visa Services Ltd | Hospitality | 2025 |
| Sparkles Healthcare Recruitment Agency Ltd | Administrative & support | 2019 |
| Sparty Limited | Construction | 2019 |
| Special Security Group Ltd | Administrative & support | 2024 |
| Speech With ME Ltd | Education | 2018 |
| Speedwing Cars Ltd | Transport & logistics | 2024 |
| Speedy Parcel Cards Ltd | Wholesale & retail | 2025 |
| Sphear Media Ltd | Information & communication | 2025 |
| Spice&Tide Limited | Wholesale & retail | 2024 |
| Splendid House Property Solutions Ltd | Wholesale & retail | 2017 |
| SPM Ventures Limited | Real estate | 2023 |
| Sports Travel Tours (Europe) Limited | Administrative & support | 2006 |
| Spot on Constructions Limited | Construction | 2020 |
| Spriint Limited | Information & communication | 2016 |
| Spriint Solutions Limited | Information & communication | 2025 |
| SQL DEV Ltd | Information & communication | 2010 |
| Square Leisure and Entertainment Limited | Hospitality | 2022 |
| SRA World Limited | Hospitality | 2026 |
| Srija Systems Ltd | Information & communication | 2016 |
| Srmc Club Ltd | Other services | 2024 |
| SRN Design & Build Ltd | Construction | 2023 |
| SRS Partners Limited | Hospitality | 2015 |
| SRT Group Ltd | Construction | 2024 |
| Srub Limited | Information & communication | 2026 |
| SRV Associates UK Ltd | Hospitality | 2026 |
| SS Nagra Haulage Limited | Construction | 2025 |
| SS Nagra Limited | Transport & logistics | 2016 |
| SS Public House Limited | Hospitality | 2018 |
| SSM Health Ltd | Health & social care | 2024 |
| SSQ Property Development Limited | Real estate | 2022 |
| Sssn Builder's Limited | Construction | 2014 |
| ST Mark Group Ltd | Transport & logistics | 2023 |
| ST Anthony Foods Ltd | Hospitality | 2020 |
| ST. Mark (UK) Properties Ltd | Real estate | 2022 |
| ST. Mark Services Limited | Wholesale & retail | 1994 |
| St.Marcos Holdings Limited | Real estate | 2008 |
| Stabler Consulting Ltd | Information & communication | 2024 |
| Stacey's Handmade Jewellery Ltd | Manufacturing | 2025 |
| Stallion City Cars Ltd | Transport & logistics | 2026 |
| Stallion IT Consultant Limited | Information & communication | 2013 |
| Stallion Rider Ltd | Wholesale & retail | 2024 |
| Standard Paving & Groundwork Ltd | Construction | 2024 |
| Stanionis Limited | Construction | 2026 |
| Star Bakers Limited | Manufacturing | 2024 |
| Star Express Handling Ltd | Transport & logistics | 2022 |
| Star Services 1 Ltd | Water & waste | 2025 |
| Starling Associates Ltd | Professional & scientific | 2020 |
| Station Road Residents Limited | Other services | 1999 |
| Station Snack Stop Ltd | Hospitality | 2025 |
| Staywell Homes Ltd | Hospitality | 2025 |
| Staywell Solutions Ltd | Real estate | 2024 |
| Stayze Ltd | Real estate | 2025 |
| STC Construction Services Ltd | Construction | 2015 |
| Steady State Works Limited | Professional & scientific | 2026 |
| Stealth & Hasty Ltd | Arts & recreation | 2021 |
| Stean Ltd | Wholesale & retail | 2025 |
| Stefan Screeding UK Ltd | Construction | 2023 |
| Step by Step Saloon Ltd | Other services | 2019 |
| Sterling Properties Investor Ltd | Real estate | 2022 |
| Sterlinglane Limited | Wholesale & retail | 2022 |
| Sticknobillslondon Ltd | Professional & scientific | 2025 |
| Stockley Business Services Limited | Professional & scientific | 2019 |
| Stoke Properties Limited | Professional & scientific | 2013 |
| Stonebricks Development Ltd | Real estate | 2025 |
| Storm Stunts Ltd | Professional & scientific | 2016 |
| Strands Unisex Hair Dressers Ltd | Other services | 2022 |
| Stratix AI Ltd | Wholesale & retail | 2025 |
| Straw Consulting Ltd | Information & communication | 2015 |
| Strhs Ltd | Hospitality | 2024 |
| Structured Way Ltd | Information & communication | 2026 |
| SUBHAN0786 Limited | Wholesale & retail | 2026 |
| Subu UK Ltd | Other services | 2025 |
| Sudeley Leisure Limited | Hospitality | 2019 |
| Sugarshaks Ltd | Health & social care | 2026 |
| Sukh Barbers Ltd | Other services | 2025 |
| Sukh Logistics Limited | Transport & logistics | 2024 |
| Sukh Toor Construction Ltd | Construction | 2018 |
| Sultan Trading Ltd | Other services | 2017 |
| Suly Tech Ltd | Information & communication | 2017 |
| Sumerru Limited | Extraterritorial | 2011 |
| Summer Gill Limited | Real estate | 2024 |
| Summerhouse Construction Limited | Information & communication | 2026 |
| Sun Health Solutions Limited | Professional & scientific | 2020 |
| Sunark Limited | Wholesale & retail | 2000 |
| Sunflower Luxury Tours Ltd | Administrative & support | 2023 |
| Sunlite Electrical Limited | Transport & logistics | 2014 |
| Sunnybank Homes Ltd | Real estate | 2026 |
| Sunray Entertainment Limited | Arts & recreation | 2025 |
| Sunray Property Investments Ltd | Financial services | 2016 |
| Sunray Realty Limited | Real estate | 2024 |
| Sunrise 786 Ltd | Hospitality | 2022 |