| Shaifi Traders Limited | Wholesale & retail | 2024 |
| Shalom Worldwide Services Limited | Health & social care | 2011 |
| Shanelle's Sea Moss Ltd | Wholesale & retail | 2022 |
| Shanty Photography Ltd | Professional & scientific | 2022 |
| Sharazay Group Ltd | Professional & scientific | 2025 |
| Sharif Group Properties Limited | Real estate | 2020 |
| Shayas Developments Limited | Construction | 2019 |
| Sheba Chauffeur Services Limited | Transport & logistics | 2025 |
| Sher Group of Builders Ltd | Construction | 2020 |
| Shergrafix Limited | Extraterritorial | 1992 |
| Shine Logistics Ltd | Transport & logistics | 2025 |
| Shine Route Ltd | Real estate | 2024 |
| Shine Star Properties Ltd | Real estate | 2023 |
| Shinos Limited | Hospitality | 2022 |
| Shipps Building Services Ltd | Construction | 2020 |
| Shipps Enterprises Ltd | Hospitality | 2023 |
| Shireen Hair & Beauty Ltd | Other services | 2026 |
| Shivani Superstores Limited | Wholesale & retail | 2011 |
| Shivvy Property Holdings Ltd | Real estate | 2025 |
| SHL Finance Ltd | Financial services | 2022 |
| Shor Bazaar Foods Ltd | Hospitality | 2025 |
| Shri Krishna Builders Ltd | Construction | 2024 |
| Shynara Group Limited | Wholesale & retail | 2026 |
| Siddall Group Limited | Professional & scientific | 2000 |
| Siddall Medequip Limited | Professional & scientific | 2011 |
| Sidhu Movers Ltd | Transport & logistics | 2018 |
| Sierra Light Ltd | Health & social care | 2018 |
| Sightsol Ltd | Wholesale & retail | 2026 |
| Sigmaa Ltd | Information & communication | 2026 |
| Signature Concierge Ltd | Administrative & support | 2022 |
| Signature Property Investment Group Ltd | Real estate | 2023 |
| Signature Repair Limited | Wholesale & retail | 2026 |
| Signature Smart Spaces Limited | Construction | 2023 |
| Silimed UK Limited | Wholesale & retail | 2023 |
| Silvercraft Limited | Hospitality | 2013 |
| Simla Paradise Ltd | Hospitality | 2018 |
| Simplu Storage Ltd | Arts & recreation | 2026 |
| Simpson Carpentry Ltd | Construction | 2011 |
| Singh Service Partner Ltd | Transport & logistics | 2025 |
| Singh's Enterprises Ltd | Wholesale & retail | 2016 |
| Singh-Duhre Properties LLP | | 2020 |
| Singhs Investment Ltd | Real estate | 2024 |
| Sipson Autos Ltd | Wholesale & retail | 2023 |
| Sipson Public House Limited | Hospitality | 2017 |
| SIR Roofing Solutions Ltd | Construction | 2019 |
| Site Solution Services Limited | Construction | 2015 |
| Sizzlin Hutt Ltd | Hospitality | 2025 |
| SJB Gynaecology Ltd | Health & social care | 2024 |
| SJD Technologies Limited | Information & communication | 2013 |
| SK 786 Motors Limited | Wholesale & retail | 2019 |
| SK Jando Properties Ltd | Real estate | 2025 |
| Skara Limited | Real estate | 2022 |
| Skillhub Recruitment Ltd | Professional & scientific | 2025 |
| Skin Intuition Ltd | Manufacturing | 2019 |
| Skinthetics Clinic Ltd | Health & social care | 2022 |
| SKM Double Glazing Ltd | Construction | 2025 |
| SKS Consultant UK L Limited | Administrative & support | 2010 |
| Sky Integrated Services Limited | Administrative & support | 2026 |
| Sky Line Ticketing UK Ltd | Administrative & support | 2024 |
| Sky Nights Ltd | Hospitality | 2016 |
| Sky S Developments Limited | Construction | 2017 |
| Sky X Ltd | Wholesale & retail | 2021 |
| Skyassist Ltd | Administrative & support | 2025 |
| Skycomm Energy Limited | Construction | 2024 |
| Skycomm Vertiports Limited | Construction | 2024 |
| Skyebella Solutions Limited | Administrative & support | 2025 |
| Skyhigh Production UK Ltd | Information & communication | 2012 |
| Skyland Transport Ltd | Transport & logistics | 2016 |
| Skylink Airport Transfers Ltd | Transport & logistics | 2024 |
| Skyone Products UK Ltd | Other services | 2020 |
| Skyway Tech Service Ltd | Wholesale & retail | 2023 |
| Small Marketing Solutions Limited | Professional & scientific | 2021 |
| Smart College Ltd | Education | 2021 |
| Smart Move London Ltd | Transport & logistics | 2019 |
| Smart Work Research Ltd | Professional & scientific | 2023 |
| Smartech International Ltd | Information & communication | 2022 |
| Smarterdeco Ltd | Construction | 2024 |
| Smash and Slice London Ltd | Hospitality | 2025 |
| SMH Property Management Limited | Households | 2018 |
| Smile Savers 32 Limited | Administrative & support | 2013 |
| Smoothmotors UK Limited | Administrative & support | 2016 |
| Smother Pet Food Ltd | Wholesale & retail | 2024 |
| SMV Properties Investments Limited | Real estate | 2019 |
| Snapcolour Ltd | Other services | 2014 |
| Snowmind Limited | Information & communication | 2025 |
| SNS Softtech Limited | Information & communication | 2015 |
| Softech Development Limited | Wholesale & retail | 2013 |
| Softlight Ltd | Information & communication | 2019 |
| Sokhal Group Limited | Construction | 2024 |
| SOL Builders Ltd | Construction | 2015 |
| Solace Markets Ltd | Professional & scientific | 2026 |
| Solem Ltd. | Professional & scientific | 2024 |
| Soliscomm Energy Limited | Construction | 2026 |
| Soliscomm/Revival Homes Limited | Construction | 2025 |
| Soliscommrh Limited | Construction | 2025 |
| Solufai Technologies Limited | Information & communication | 2025 |
| Sonpat Decorating Ltd | Information & communication | 2019 |
| Sonvan Ltd | Real estate | 2020 |
| Sorin Work Force Limited | Construction | 2016 |
| Soutar Enterprises Limited | Information & communication | 2017 |