| Elite Construction Midlands Ltd | Construction | 2022 |
| Elite Direct Ltd | Wholesale & retail | 2019 |
| Elite Energy + Ltd | Construction | 2022 |
| Elite Maintenance Engineering Services Limited | Professional & scientific | 2019 |
| Elite Plumbing & Heating Contractors Ltd | Construction | 2020 |
| Ellisen Limited | Health & social care | 2021 |
| Elswall Limited | Transport & logistics | 2022 |
| Elvnox Ltd | Information & communication | 2025 |
| Elyas Deliveries Limited | Transport & logistics | 2025 |
| Elyasi Brothers Hairstyle Ltd | Other services | 2024 |
| Emerald Solutions Homes Ltd | Real estate | 2025 |
| Emil Transport Ltd | Transport & logistics | 2016 |
| Emmcee Ltd | Information & communication | 2018 |
| Empire BGS Limited | Extraterritorial | 2023 |
| Empire Investment Services Ltd | Real estate | 2020 |
| Empowering People in Change - CIC | Education | 2018 |
| Energy Recovery Services (West Midlands) Ltd | Water & waste | 2013 |
| Enervive Ltd | Professional & scientific | 2025 |
| Enexora Limited | Construction | 2025 |
| Enmur Limited | Hospitality | 2020 |
| Ennit Property Limited | Real estate | 2007 |
| Ep&Ms Limited | Manufacturing | 2012 |
| Epms Global Holdings Ltd | Manufacturing | 2024 |
| ERA John Ltd | Wholesale & retail | 2025 |
| ES Site Services Limited | Construction | 2015 |
| Esale Electronics Limited | Wholesale & retail | 2010 |
| Esprit EOT Limited | Professional & scientific | 2025 |
| Esprit Group UK Limited | Financial services | 2001 |
| Esprit Midland Limited | Manufacturing | 1996 |
| Esprit Services Limited | Manufacturing | 1997 |
| Esprit UK Limited | Construction | 2001 |
| Essence Inn Ltd | Hospitality | 2025 |
| Essential Supported Living Ltd | Real estate | 2023 |
| Estate Elegance Rentals Ltd | Real estate | 2023 |
| Etbelle Ltd | Wholesale & retail | 2026 |
| Eternal Harmony Ltd | Arts & recreation | 2024 |
| Etra Group Ltd | Information & communication | 2019 |
| EU2UK Logistic Solution Ltd | Transport & logistics | 2016 |
| Euro Dean Limited | Transport & logistics | 2015 |
| Euro Express Mini Market Ltd | Wholesale & retail | 2021 |
| Euro Glazing (UK) Limited | Construction | 2010 |
| Eurogate Logistics Group Ltd | Transport & logistics | 2026 |
| Eurohire Vehicle Rentals (Birmingham) Limited | Administrative & support | 1985 |
| Eurohire Vehicle Rentals Limited | Professional & scientific | 1985 |
| Europa Hotels Limited | Hospitality | 2016 |
| Eva-Nicol (UK) Limited | Health & social care | 2014 |
| Eva-Nicol Properties Limited | Real estate | 2025 |
| Eveokontinental Ltd | Wholesale & retail | 2020 |
| Everest Partners Limited | Real estate | 2025 |
| Evergreen Construction Plus Ltd | Construction | 2026 |
| Evermartuk Ltd | Wholesale & retail | 2025 |
| Evermore Clients Ltd | Wholesale & retail | 2025 |
| Everprep Ltd | Real estate | 2020 |
| Everseal Windows and Doors Limited | Manufacturing | 2026 |
| Evershine Windows and Doors Ltd | Manufacturing | 2019 |
| Evitts Haulage Limited | Transport & logistics | 2011 |
| Evitts Transport Ltd | Transport & logistics | 2010 |
| Evoke Building Services Ltd | Manufacturing | 2022 |
| Evolve Learning West Bromwich Ltd | Education | 2024 |
| Exact Solutions Midlands Limited | Wholesale & retail | 2025 |
| Excel Midlands Ltd | Health & social care | 2018 |
| Excellence Property Group Ltd | Real estate | 2025 |
| EXCELR8 SCE C.I.C. | Education | 2020 |
| Exchangists Ltd | Arts & recreation | 2012 |
| Express Cars Midlands Ltd | Wholesale & retail | 2018 |
| Express Freight (International) Ltd | Transport & logistics | 2023 |
| Express Real Estate Ltd | Construction | 2022 |
| Express Slitting Services Ltd | Administrative & support | 2017 |
| Express Windows UK Ltd | Construction | 2018 |
| Expresscore Logistics Limited | Administrative & support | 2026 |
| Extra Investments Ltd | Real estate | 2021 |
| Ezzentials+ Ltd | Real estate | 2022 |
| F and U Limited | Wholesale & retail | 2019 |
| F Hova Limited | Health & social care | 2015 |
| F Style Limited | Other services | 2021 |
| F&A Properties Investment Ltd | Real estate | 2025 |
| F&M Services Ltd | Information & communication | 2012 |
| F&Nmoverssolutions Ltd | Transport & logistics | 2026 |
| F&S Luxe Ltd | Information & communication | 2025 |
| F.H Traders Ltd | Wholesale & retail | 2021 |
| F.T. Express Ltd | Transport & logistics | 2026 |
| Faaz Foods Ltd | Manufacturing | 2024 |
| FAB the Driver Ltd | Transport & logistics | 2021 |
| Fade City Ltd | Other services | 2025 |
| Fadhl Clothing Ltd | Wholesale & retail | 2024 |
| Faithy’S Luxe Limited | Other services | 2022 |
| FAJ Transformation Consultancy Ltd | Professional & scientific | 2017 |
| Falcon Ebike & Scooters Ltd | Wholesale & retail | 2026 |
| Falcon Welding Solutions Ltd | Other services | 2025 |
| Faraon Limited | Transport & logistics | 2008 |
| Farrell's Exotic Ltd | Wholesale & retail | 2019 |
| Fashion & Designs Ltd | Wholesale & retail | 2026 |
| Fashion by Duda Limited | Real estate | 2016 |
| Fast Fit Clutch and Service Centre Limited | Wholesale & retail | 2019 |
| Fast Lane 1 Ltd | Wholesale & retail | 2026 |
| Fast Parcels Direct Limited | Transport & logistics | 2006 |
| Fast Stock Limited | Wholesale & retail | 2006 |
| Fast Track Automotive Ltd | Wholesale & retail | 2020 |
| Fastline Travel Limited | Transport & logistics | 2008 |
| Fasttrackphysios Ltd | Health & social care | 2015 |