| Smartcare Pharmacy Ltd | Wholesale & retail | 2013 |
| Smartcfo Ltd | Information & communication | 2025 |
| Smartdrop Logistics Limited | Transport & logistics | 2026 |
| Smarterphone Limited | Professional & scientific | 2004 |
| Smartguide Travel Ltd | Hospitality | 2008 |
| Smartlandlord Ltd | Real estate | 2022 |
| Smartpro Tech Solutions Limited | Wholesale & retail | 2022 |
| Smartq Limited | Information & communication | 2015 |
| Smartshop Communications Ltd | Other services | 2015 |
| Smash Burgers N Wingz Ltd | Hospitality | 2025 |
| Smashcuff Limited | Information & communication | 2025 |
| Smashpoint Padel Ltd | Arts & recreation | 2025 |
| Smile More Marketing Limited | Professional & scientific | 2015 |
| Smile Upgraders Limited | Health & social care | 2022 |
| Smiler Construction Ltd | Construction | 2026 |
| Smilesbyjag Limited | Health & social care | 2023 |
| Smilesforever Ltd | Wholesale & retail | 2023 |
| Smilewales Limited | Health & social care | 2021 |
| Smitadas Limited | Information & communication | 2012 |
| SML Decorating Ltd | Construction | 2023 |
| Smooth Recovery Limited | Transport & logistics | 2017 |
| Smoothex Interiors Ltd | Construction | 2024 |
| SMP Enterprises Limited | Administrative & support | 2022 |
| SMP Repairs Limited | Manufacturing | 2023 |
| SMQ 84 a Ltd | Real estate | 2022 |
| SMQ 84 B 2 Ltd | Real estate | 2024 |
| SMQ 84 B Ltd | Real estate | 2022 |
| SMQ 84 B One Ltd | Real estate | 2024 |
| SMQ 84 C Ltd | Real estate | 2025 |
| Smrc Holdings Ltd | Real estate | 2026 |
| Smruti Patni Ltd | Wholesale & retail | 2024 |
| SMS Group Ltd | Information & communication | 2016 |
| SMS Home Improvement Ltd | Construction | 2024 |
| Smsentertainment Ltd | Arts & recreation | 2022 |
| SMT Travel Ltd | Transport & logistics | 2017 |
| Smtejani Holdings Ltd | Real estate | 2017 |
| Smtejani Ltd | Administrative & support | 2016 |
| SMY0 Limited | Construction | 2026 |
| Smyrna Services Ltd | Professional & scientific | 2024 |
| Snacks Revolution Holdings Ltd | Financial services | 2016 |
| Snaim Ltd | Health & social care | 2024 |
| Snaps Property Limited | Real estate | 2013 |
| Snapsupp Ltd | Wholesale & retail | 2025 |
| Snatchable Limited | Information & communication | 2018 |
| SNB Associates Ltd | Construction | 2018 |
| Sneakfix Ltd | Wholesale & retail | 2025 |
| SNK Financial Ltd | Administrative & support | 2012 |
| SNK Medicare Ltd | Health & social care | 2025 |
| SNL Enterprise Limited | Other services | 2017 |
| Snoozeville Ltd | Households | 2024 |
| SNP Medicare Ltd | Wholesale & retail | 2020 |
| SNP Solutions Ltd | Other services | 2018 |
| SNR Assets Limited | Real estate | 2023 |
| SNR Retail Ltd | Wholesale & retail | 2023 |
| SNR Technology Limited | Information & communication | 2023 |
| SNS Capital Limited | Real estate | 2018 |
| SNS Residence Ltd | Real estate | 2025 |
| SNS Superstore UK Limited | Other services | 2018 |
| Snzsiddique Ltd | Real estate | 2025 |
| Soba Design Consultancy Ltd | Professional & scientific | 2025 |
| Sochi UK Ltd | Wholesale & retail | 2018 |
| Social Tadka Ltd | Hospitality | 2024 |
| Social Thali Ltd | Hospitality | 2025 |
| Soda Associates Limited | Professional & scientific | 2022 |
| Sodai Sushi Ltd | Hospitality | 2020 |
| Sofiart Construction Ltd | Construction | 2022 |
| Sofra E Malesise Ltd | Hospitality | 2026 |
| Soft Tech Media Ltd | Information & communication | 2017 |
| Soft Technology Ltd | Wholesale & retail | 2004 |
| Softkey Trading Ltd | Wholesale & retail | 2025 |
| Softlux Cleaning Services Ltd | Administrative & support | 2025 |
| Softplus Ltd | Information & communication | 2024 |
| Softtech Digital Solutions Limited | Information & communication | 2023 |
| Sofu Coffee Limited | Manufacturing | 2024 |
| Soham Services Ltd | Professional & scientific | 2024 |
| Soin Contracts Ltd | Professional & scientific | 2014 |
| Soju Kitchen Ltd | Manufacturing | 2021 |
| Soka London Limited | Wholesale & retail | 2026 |
| SOL Events Ltd | Administrative & support | 2025 |
| Sola Collection Ltd | Hospitality | 2026 |
| Solai Holdings Limited | Other services | 1985 |
| Solai House Limited | Real estate | 2017 |
| Solai Services Limited | Administrative & support | 1985 |
| Solai USA Limited | Other services | 2011 |
| Solarline Energy Ltd | Construction | 2023 |
| Solemuse Ltd | Wholesale & retail | 2026 |
| Solid Piling Ltd | Construction | 2023 |
| Solid Solo Ltd | Wholesale & retail | 2021 |
| Solomon Capital LLP | | 2011 |
| Solomon's Mind Ltd | Professional & scientific | 2016 |
| Solthermo Limited | Manufacturing | 2023 |
| Solunar Export Ltd | Wholesale & retail | 2026 |
| Solution X Fitness Ltd | Health & social care | 2018 |
| Solved Tech Limited | Information & communication | 2026 |
| Sombor Ltd | Wholesale & retail | 2023 |
| Somief Limited | Wholesale & retail | 2024 |
| Somika London Limited | Administrative & support | 2012 |
| Somin R Ltd | Construction | 2021 |
| Sona Services Ltd | Construction | 2015 |
| Sonal Fashion Ltd | Wholesale & retail | 2022 |