| Sara Zubair Ltd | Transport & logistics | 2026 |
| Sarah Khosravani Ltd | Health & social care | 2023 |
| Sarauk Limited | Hospitality | 2025 |
| Sardar JI Fresh Vegetables and Fruits Ltd | Wholesale & retail | 2024 |
| Saree Illam Ltd | Wholesale & retail | 2026 |
| Sarh Motors MOT Limited | Wholesale & retail | 2017 |
| Sarthi Enterprises Ltd | Wholesale & retail | 2025 |
| Sarunas Enterprises Ltd | Construction | 2024 |
| Sarv Properties Ltd | Real estate | 2022 |
| Sarvopari Properties Limited | Real estate | 2021 |
| SAS Damian Construction Ltd | Construction | 2021 |
| SAS Wholesale Limited | Wholesale & retail | 2023 |
| Sasa Global Ltd | Professional & scientific | 2023 |
| Sasa New Ltd | Wholesale & retail | 2025 |
| Sasi Caterers Limited | Hospitality | 2019 |
| Sasi International Limited | Real estate | 2021 |
| Sasi NG Ltd | Construction | 2025 |
| Saska Investments Ltd | Real estate | 2024 |
| Sastha Productions Limited | Wholesale & retail | 2023 |
| SAT Dham | Other services | 2025 |
| Satguru Travel and Tourism Limited | Transport & logistics | 2017 |
| Saththiyavan Trust | Health & social care | 2017 |
| Sathu SAS Properties Ltd | Real estate | 2026 |
| Sathy Estates (JS) Ltd | Real estate | 2018 |
| Sathy Estates (Lettings) Ltd | Real estate | 2010 |
| Sathy Estates (London) Ltd | Real estate | 2015 |
| Satnam Food & Wine Ltd | Wholesale & retail | 2024 |
| Satpathy Engineering Consultancy Ltd | Professional & scientific | 2016 |
| Satrapa Ltd | Wholesale & retail | 2019 |
| Satta's Kitchens Ltd | Hospitality | 2025 |
| Sattva Living Limited | Wholesale & retail | 2024 |
| Saturn Building Maintenance Limited | Construction | 2019 |
| Satyanam Ltd | Hospitality | 2017 |
| Saunderton Road 1962 Limited | Extraterritorial | 2014 |
| SAV Management UK Ltd | Real estate | 2023 |
| Savacco SV Ltd | Wholesale & retail | 2014 |
| Savan Fast Food Ltd | Hospitality | 2018 |
| Savannah Lounge Ltd | Hospitality | 2014 |
| Savannah Sports Limited | Arts & recreation | 2025 |
| Save BRO Limited | Professional & scientific | 2003 |
| Save One Child Stem CIC | Information & communication | 2026 |
| Savita Bailur Limited | Other services | 2016 |
| Savitech Consulting Ltd | Information & communication | 2024 |
| Savk Limited | Wholesale & retail | 2025 |
| Savvy Crew Limited | Other services | 2021 |
| Savy Management Ltd | Real estate | 2025 |
| SAW Sharpening Services Ltd | Wholesale & retail | 2013 |
| Sawariya Store Ltd | Hospitality | 2025 |
| Sawlt Ltd | Manufacturing | 2022 |
| Saxon Court (Northwood) RTM Company Limited | Households | 2025 |
| Saxonbridge Investments Limited | Real estate | 2002 |
| Saxonymasters Ltd | Water & waste | 2018 |
| Saxxassociates.Com Ltd | Other services | 2025 |
| Saya Enterprises Limited | Manufacturing | 1992 |
| Sayed.Fatimi Ltd | Wholesale & retail | 2021 |
| Says IT Limited | Information & communication | 2019 |
| SB Boxpark Wembley Ltd | Hospitality | 2018 |
| SB Equity Ltd | Real estate | 2026 |
| SB Infinite Captures Ltd | Information & communication | 2026 |
| SB Pinnacle INV Ltd | Real estate | 2022 |
| SBB Construction Limited | Construction | 2016 |
| SBC Solutions Ltd | Professional & scientific | 2013 |
| Sbchaudhary Ltd | Construction | 2025 |
| Sbcustomz Ltd | Wholesale & retail | 2023 |
| SBM Auto Motors Ltd | Wholesale & retail | 2018 |
| SBR Legacy Limited | Wholesale & retail | 2025 |
| SBS Consulting Solutions Ltd | Information & communication | 2008 |
| SBS Consulting Strategies Ltd | Professional & scientific | 2017 |
| Sbsd Investments Ltd | Real estate | 2020 |
| Scala Surgical Limited | Administrative & support | 2005 |
| Scandha Ltd | Transport & logistics | 2025 |
| Scatterbrain Films Limited | Information & communication | 2013 |
| Scenic Aviation Limited | Administrative & support | 1981 |
| Scholar Earth Limited | Education | 2024 |
| Scholar Solutions Ltd | Professional & scientific | 2024 |
| Schwarzwhite Limited | Administrative & support | 2014 |
| Science and Technology Centre Limited | Education | 2023 |
| Science Media LAB Limited | Information & communication | 2025 |
| Science Research Limited | Professional & scientific | 2012 |
| Scinan Limited | Other services | 2015 |
| Scirocco Property Holdings Ltd | Real estate | 2025 |
| Scorpionverse Limited | Transport & logistics | 2026 |
| Scotiland Horizontal Drilling HDD Ltd | Construction | 2020 |
| SCP Ceramic Limited | Wholesale & retail | 2025 |
| SCP Group Trading Ltd | Manufacturing | 2024 |
| Screamedia Ltd | Professional & scientific | 2020 |
| Screen ELF Ltd | Information & communication | 2017 |
| Scripter Digital Limited | Information & communication | 2025 |
| Sculpt Fitness Limited | Arts & recreation | 2025 |
| SD & Brothers Ltd | Wholesale & retail | 2020 |
| SD UK Imports Limited | Wholesale & retail | 2022 |
| SDP Aesthetics Limited | Health & social care | 2023 |
| Sdvelani Ltd | Real estate | 2026 |
| Sea Green Holdings Limited | Financial services | 2015 |
| Seafood Galore Ltd | Hospitality | 2019 |
| Seafoodnightss Ltd | Hospitality | 2026 |
| Seafoods London Ltd | Wholesale & retail | 2019 |
| Seagal's Products Ltd | Wholesale & retail | 2019 |
| Sealabs Limited | Transport & logistics | 2024 |
| Sealearn UK Limited | Financial services | 2025 |