| Saffron Food and Drinks Limited | Hospitality | 2024 |
| Saffron Roots (PVT) Ltd | Wholesale & retail | 2025 |
| Saftytax Ltd | Transport & logistics | 2021 |
| Sagaar General Trading Ltd | Administrative & support | 2025 |
| Sagana Jewellers Limited | Wholesale & retail | 2004 |
| Sagar Property Development Limited | Real estate | 2018 |
| Sagar Scientific Communications Limited | Professional & scientific | 2015 |
| Sagitaries Limited | Construction | 2018 |
| Sagitter Training Ltd | Administrative & support | 2014 |
| SAGITTER1 Limited | Professional & scientific | 2009 |
| SAH Security Ltd | Administrative & support | 2023 |
| Saha Anaesthetics Limited | Health & social care | 2019 |
| Sahajanand Properties Limited | Real estate | 2018 |
| Sahara Foods Ltd | Hospitality | 2018 |
| Saharan Ltd | Administrative & support | 2021 |
| Sahas OPS Limited | Information & communication | 2023 |
| Sahee Transport Ltd | Transport & logistics | 2023 |
| Sahul UK Limited | Administrative & support | 2009 |
| Sahutogullari Ltd | Manufacturing | 2026 |
| SAI Jyoti Day Nursery Limited | Health & social care | 2019 |
| SAI Jyoti Limited | Wholesale & retail | 2013 |
| SAI LA Express Ltd | Wholesale & retail | 2024 |
| SAI Logistics Wembley Ltd | Wholesale & retail | 2021 |
| SAI Marketplace Limited | Wholesale & retail | 2025 |
| SAI Moto Limited | Wholesale & retail | 2024 |
| SAI Vinesh Investments Ltd | Real estate | 2024 |
| Sai-Com Limited | Information & communication | 2021 |
| Saibaba Pooja Services Ltd | Other services | 2019 |
| Saikon Enterprise Limited | Information & communication | 2014 |
| Saikrupa Services Limited | Administrative & support | 2023 |
| Sainath Travel Ltd | Wholesale & retail | 2025 |
| Saint Knox Limited | Wholesale & retail | 2019 |
| Saint Mary's Restaurant Ltd | Hospitality | 2018 |
| Saint-Trésor Ltd | Wholesale & retail | 2024 |
| Saira Traders Ltd | Wholesale & retail | 2022 |
| Sairays Property Management Limited | Administrative & support | 2016 |
| Saiya Limited | Real estate | 2019 |
| Sajan Promotions Limited | | 2005 |
| Saji Jewellery Limited | Wholesale & retail | 2025 |
| Sajitarium Limited | Transport & logistics | 2025 |
| Sakhee Trading Ltd | Wholesale & retail | 2017 |
| Sakshar Ltd | Wholesale & retail | 2014 |
| Sakshis Kitchen UK Ltd | Hospitality | 2025 |
| Sakura Motors London Ltd | Wholesale & retail | 2026 |
| Sales Event Limited | Transport & logistics | 2007 |
| Salesandlettings Estate Agents Limited | Real estate | 2016 |
| Salesandlettings.Com Estate Agents Ltd | Real estate | 2012 |
| Salim Adam Ltd | Information & communication | 2014 |
| Salma P Ltd | Construction | 2022 |
| Salomeh Architecture and Interior Design Ltd | Professional & scientific | 2021 |
| Salonish Ltd | Health & social care | 2023 |
| Salthill Properties Limited | Construction | 2016 |
| Salvitrading Limited | Wholesale & retail | 2026 |
| SAM Accountants (UK) Ltd | Professional & scientific | 2014 |
| Sam's Pizza Limited | Wholesale & retail | 2019 |
| Samamiah (Shipping) Enterprise Limited | Transport & logistics | 2020 |
| Samar Investment Holdings Limited | Extraterritorial | 2026 |
| Samaya Saba Limited | Other services | 2015 |
| Samedi Group Ltd | Administrative & support | 2026 |
| Sameeh Zubairi Ltd | Professional & scientific | 2006 |
| Sameer Shukla Limited | Wholesale & retail | 2019 |
| Sami E Investments Ltd | Financial services | 2025 |
| Samm Property Limited | Real estate | 2022 |
| Samp Investments Limited | Real estate | 2020 |
| Samp Properties Limited | Real estate | 2020 |
| Samraat Properties Ltd | Real estate | 2016 |
| Samrddhi Ltd | Wholesale & retail | 2025 |
| Sams Barber Shop Wembley Limited | Other services | 2022 |
| Sams Linen Hire Ltd | Other services | 2018 |
| SAMS4141 Properties Limited | Real estate | 2020 |
| SAN Damiano Corporation (London) Ltd | Health & social care | 2019 |
| SAN Damiano Properties Ltd | Real estate | 2022 |
| Sana Diamond Ltd | Real estate | 2017 |
| Sanatan Events C.I.C. | Arts & recreation | 2024 |
| Sancom Impex (UK) Ltd | Manufacturing | 2018 |
| Sandy Builders Ltd | Construction | 2025 |
| Sangit Express Ltd | Wholesale & retail | 2024 |
| Sanglakh Market Ltd | Wholesale & retail | 2025 |
| Sanity OS Ltd | Information & communication | 2015 |
| Sanj Services UK Ltd | Wholesale & retail | 2019 |
| Sanjana Textile Limited | Wholesale & retail | 2017 |
| Sanjil Traders Limited | Construction | 2025 |
| Sanjivani Consultants Ltd | Information & communication | 2012 |
| Sankalp Marketing Limited | Wholesale & retail | 2025 |
| Sannet Apartments Limited | Real estate | 2017 |
| Sanopti Limited | Health & social care | 2010 |
| Sanras IT Limited | Information & communication | 2024 |
| Sansu Limited | Wholesale & retail | 2023 |
| Santos Contractors Ltd | Construction | 2026 |
| Sanus Medical Ltd | Health & social care | 2018 |
| Sany Ltd | Hospitality | 2026 |
| SAP Group Ltd | Wholesale & retail | 2024 |
| Sapele Construction Limited | Construction | 2019 |
| Sapjen Ltd | Real estate | 2017 |
| Sapna Swaly Consulting Limited | Professional & scientific | 2023 |
| Sapphire Law Ltd | Professional & scientific | 2016 |
| Sara Damergi Ltd | Information & communication | 2013 |
| Sara Global Limited | Wholesale & retail | 2017 |
| Sara Iqbal Limited | Transport & logistics | 2022 |
| Sara Studios Ltd | Information & communication | 2015 |