| ERA of Eben Limited | Wholesale & retail | 2024 |
| Eraz Avenue Ltd | Wholesale & retail | 2025 |
| Erbil Investment Ltd | Real estate | 2019 |
| Eremus Limited | Professional & scientific | 2017 |
| Eresco Ltd | Transport & logistics | 2017 |
| Ergostar Ltd | Wholesale & retail | 2002 |
| Eridana Ltd | Hospitality | 2011 |
| Eriks Driving School and Transport Service Ltd | Transport & logistics | 2025 |
| Ernest Build & Brill Northants Ltd | Construction | 2025 |
| Ernest Healthcare Recruitment Ltd | Administrative & support | 2025 |
| Ernposh Limited | Administrative & support | 2025 |
| Eronms Ltd | Professional & scientific | 2023 |
| Erris Civil Engineering Ltd | Construction | 2014 |
| Ertu Ltd | Wholesale & retail | 2020 |
| Eryk Ramps Ltd | Manufacturing | 2025 |
| Escooterclinic Limited | Wholesale & retail | 2020 |
| Esit Holdings Ltd | Financial services | 2018 |
| ESP Asset Management Ltd | Administrative & support | 2006 |
| ESP Living Ltd | Real estate | 2024 |
| ESSENCE24 Care Ltd | Public administration | 2024 |
| Essentia Solutions Ltd | Health & social care | 2018 |
| Esthetus Ltd | Other services | 2026 |
| Esvey Holdings Ltd | Construction | 2020 |
| Eterna Lighting Limited | Wholesale & retail | 1946 |
| Ethereal Jewellery Limited | Wholesale & retail | 2024 |
| Ethita Ltd | Information & communication | 2025 |
| ETI Logistics Support Ltd | Professional & scientific | 2015 |
| Etmad Investments Ltd | Health & social care | 2026 |
| Ettie Ltd | Wholesale & retail | 2023 |
| EU Vape Ltd | Wholesale & retail | 2026 |
| Euphoria Hair Limited | Other services | 2020 |
| Euro Auto Motors Ltd | Wholesale & retail | 2023 |
| Euro Bites (UK) Ltd | Wholesale & retail | 2009 |
| Euro Market (UK) Ltd | Wholesale & retail | 2014 |
| Euro Snacks Ltd | Wholesale & retail | 2023 |
| Eurofleet Rental Limited | Administrative & support | 1964 |
| Eurolink Technologies Ltd | Information & communication | 2024 |
| Euromaxx Wellingborough Ltd | Wholesale & retail | 2025 |
| Europe Midland Ltd | Wholesale & retail | 2024 |
| Euston Biogas Limited | Energy | 2014 |
| Euston Ventures Limited | Other services | 2021 |
| EV Charger Pro Ltd | Construction | 2021 |
| EV Contract Services Limited | Construction | 2025 |
| EVA CRM Ltd | Information & communication | 2024 |
| Evavis Ltd | Transport & logistics | 2018 |
| EVE Electrical Installations Limited | Construction | 2005 |
| Event Facilities Ltd | Hospitality | 2022 |
| Everbright Compassions Ltd | Health & social care | 2026 |
| Evercreech Renewable Energy Limited | Energy | 2017 |
| Evergreen Care Home Ltd | Health & social care | 2023 |
| Evergreen Healthcare Services Limited | Administrative & support | 2017 |
| Everhaven Ltd | Wholesale & retail | 2024 |
| Eversoclear Ltd | Information & communication | 2002 |
| Every Step Mortgages Ltd | Financial services | 2019 |
| Eviebevie Ltd | Wholesale & retail | 2014 |
| Evoke 24 Ltd | Health & social care | 2020 |
| Evolution Flooring Contractors Ltd | Construction | 2024 |
| Evolution Inns Ltd | Hospitality | 2019 |
| Evolution MOT Centre Limited | Wholesale & retail | 2015 |
| Evolution Security Systems (UK) Limited | Information & communication | 2011 |
| Evolve Business Coaching Ltd | Professional & scientific | 2021 |
| EVT Tech Ltd | Professional & scientific | 2025 |
| Exceeding (Holdings) Limited | Financial services | 2019 |
| Exceeding Investments Limited | Real estate | 2020 |
| Excel (UK) Limited | Wholesale & retail | 2009 |
| Excelerate Consultancy Limited | Professional & scientific | 2017 |
| Excelerate Group Holdings Ltd | Financial services | 2026 |
| Excelerate Ltd | Administrative & support | 2014 |
| Excelsior Business Support Services Ltd | Professional & scientific | 2023 |
| Excelsior Locum Ltd | Professional & scientific | 2026 |
| Executive Accounting Services Limited | Professional & scientific | 2006 |
| Exhorr Ltd | Wholesale & retail | 2023 |
| Expats Property Investors Ltd | Extraterritorial | 2023 |
| Experimental Industries Limited | Administrative & support | 2023 |
| Expert Mind Health Ltd | Health & social care | 2023 |
| Exploration Management Services Limited | Mining & quarrying | 2011 |
| Export Trade Services Ltd | Administrative & support | 2012 |
| Express Eyebrows & Beauty Ltd | Other services | 2022 |
| Express IT Services Limited | Other services | 2018 |
| Extra Installations and Logistics Limited | Manufacturing | 2022 |
| EY Trading Ltd | Transport & logistics | 2025 |
| EY3 Engineering Ltd | Professional & scientific | 2016 |
| EY3 Limited | Manufacturing | 2002 |
| EZ Cleans 4U Ltd | Administrative & support | 2023 |
| Ezekiel Holdings Limited | Administrative & support | 2018 |
| Ezel Pizza Ltd | Hospitality | 2025 |
| EZL Solutions Limited | Transport & logistics | 2025 |
| Ezweni Healthcare Ltd | Health & social care | 2018 |
| F E Bosworth & SON Ltd | Administrative & support | 2010 |
| F&F Desserts Limited | Hospitality | 2025 |
| F&S Consulting Limited | Information & communication | 2023 |
| FAB Footwear Limited | Wholesale & retail | 2013 |
| FAB Freigh Ltd | Transport & logistics | 2023 |
| FAB Support Limited | Health & social care | 2011 |
| Fabko Motors Ltd | Wholesale & retail | 2017 |
| Fabulous Blinds Northampton Ltd | Manufacturing | 2015 |
| Fabwell Heating & Plumbing Ltd | Construction | 2011 |
| Face to Face Recruitment Northants Limited | Administrative & support | 2010 |
| Facethings Ltd | Manufacturing | 2025 |
| Fahrer Ltd | Transport & logistics | 2024 |