| Sierra for General Trading Ltd | Wholesale & retail | 2025 |
| Sigma Maintenance and Refurbishment Ltd | Construction | 2016 |
| Simpleey Amazing Services Ltd | Wholesale & retail | 2025 |
| Sincerely, Coffee Limited | Hospitality | 2025 |
| Sinclair Global Group S.R.O Ltd | Wholesale & retail | 2023 |
| Sinera Electrical and Property Maintenance Ltd | Construction | 2021 |
| Sinera Property Maintenance Ltd | Construction | 2022 |
| Singh Warraich Construction Ltd | Construction | 2025 |
| Sinot Jewellery Limited | Wholesale & retail | 2021 |
| SIP M&E Consulting Ltd | Professional & scientific | 2025 |
| SIR Estates Ltd | Real estate | 2020 |
| Siri Technologies PVT Ltd | Information & communication | 2017 |
| Sisan Tech Ltd | Wholesale & retail | 2025 |
| Sitech Network Limited | Information & communication | 2022 |
| Siteview AR Ltd | Information & communication | 2025 |
| SIX Thames Circle Limited | Real estate | 2025 |
| SJ Primary Languages LLP | | 2020 |
| Skillentic Ltd | Information & communication | 2025 |
| Skindustry Ltd | Other services | 2023 |
| Skip the Hassle Ltd | Professional & scientific | 2024 |
| SKL Driving School Ltd | Education | 2021 |
| Sky Gadgets Limited | Wholesale & retail | 2025 |
| Sky Nails London Limited | Other services | 2025 |
| Skyss Construction Ltd. | Construction | 2017 |
| Skywalkerfightteam Limited | Education | 2024 |
| SLB Aesthetics London Ltd | Other services | 2022 |
| SLB Aesthetics Training Ltd | Education | 2024 |
| Sleep Superior Ltd | Wholesale & retail | 2024 |
| SLM Accommodations Ltd | Real estate | 2023 |
| SLM Refurbishments Limited | Real estate | 2025 |
| SLP Solution Ltd | Construction | 2021 |
| SM Retailer Ltd | Wholesale & retail | 2023 |
| SM Venues Ltd | Hospitality | 2018 |
| Smart Green Development Limited | Professional & scientific | 2024 |
| Smart Solutions Technologies Ltd | Information & communication | 2021 |
| Smarteco Cleaning Solutions Ltd | Administrative & support | 2025 |
| Smash N Vegan Ltd | Hospitality | 2024 |
| SMH Building and Electrical Services Ltd | Construction | 2023 |
| Smiots Limited | Wholesale & retail | 2021 |
| Smith Precision Design & Build Limited | Construction | 2026 |
| Smitherson Bros Limited | Information & communication | 2017 |
| SMM Consultancy Group Ltd | Information & communication | 2026 |
| Smoothrose Ltd | Wholesale & retail | 2020 |
| Smtt Solutions Limited | Information & communication | 2024 |
| Smyle Group Ltd | Education | 2018 |
| SNS Lucky Co Ltd | Construction | 2016 |
| SOF Infrastructure Limited | Professional & scientific | 2017 |
| Sofia Maria Limited | Real estate | 2003 |
| Softag Ltd | Information & communication | 2024 |
| Soma Integration Limited | Health & social care | 2026 |
| Sophie Clarke Singer Limited | Information & communication | 2021 |
| Sort MI Tax Limited | Professional & scientific | 2013 |
| SOS Medical Limited | Wholesale & retail | 2018 |
| SOS VIP Ltd | Professional & scientific | 2026 |
| Soul Innovation Ltd | Real estate | 2025 |
| Soulful Aesthetics UK Ltd | Health & social care | 2025 |
| Sound Stage Studios Ltd | Extraterritorial | 2003 |
| South East Contracts Ltd | Other services | 2018 |
| South East Sleepers Ltd | Hospitality | 2026 |
| Southeast Fire Services Ltd | Administrative & support | 2007 |
| Southspice Services Ltd | Hospitality | 2022 |
| Southspicefood Limited | Hospitality | 2024 |
| SP Partnership Limited | Wholesale & retail | 2024 |
| Space Rocket Digital Limited | Professional & scientific | 2023 |
| Specpro Buildings Limited | Construction | 2024 |
| Spin City Welling Limited | Other services | 2025 |
| Spiritual Anthropology Neural Engagement Ltd | Education | 2025 |
| Sports Injury Management Ltd | Education | 2020 |
| Sports Scene Group Ltd | Financial services | 2024 |
| Sports Scene Limited | Wholesale & retail | 2011 |
| Springfield House Children’S Home Ltd | Health & social care | 2026 |
| Spyderfit Ltd | Health & social care | 2025 |
| Square Meter Ltd | Construction | 2021 |
| Srinirushaa Ltd | Wholesale & retail | 2026 |
| SRS Plumbing Limited | Construction | 2025 |
| SS Home Solutions Ltd | Real estate | 2025 |
| SSB Solutions Ltd | Transport & logistics | 2023 |
| SSS Holdings Limited | Real estate | 2018 |
| SSS Retreat Ltd | Administrative & support | 2026 |
| ST Financial Solution Ltd | Professional & scientific | 2011 |
| Stand OUT Konsult Ltd | Hospitality | 2010 |
| Stantos Ltd | Information & communication | 2020 |
| Starshine DRY Cleaners Welling Ltd | Other services | 2019 |
| Status Bexleyheath Ltd | Arts & recreation | 2026 |
| Steady Hand Solutions Limited | Administrative & support | 2025 |
| Stelica Building Ltd | Construction | 2022 |
| Stella DUX Limited | Professional & scientific | 2020 |
| Stents Ltd | Wholesale & retail | 2023 |
| Step Two Tech Ltd | Information & communication | 2026 |
| Sterling Legal Advocate Ltd | Professional & scientific | 2026 |
| Sterling Shine Ltd | Administrative & support | 2026 |
| Stone Academy Ltd | Arts & recreation | 2018 |
| Stone Fight Shop Limited | Wholesale & retail | 2021 |
| Straightsmouth Limited | Households | 2001 |
| Stratfield House Freehold Limited | Households | 2017 |
| Street Food Kitchens Ltd | Hospitality | 2015 |
| Streets Foods Kitchens Ltd | Hospitality | 2022 |
| Strip Surge Ltd | Manufacturing | 2025 |
| Strongous Ltd | Other services | 2025 |
| Stuart Crouch Creative Limited | Professional & scientific | 2017 |