| Saha IT Solutions Limited | Information & communication | 2015 |
| Saifur Care Ltd | Health & social care | 2026 |
| Sake's Medcare Ltd | Health & social care | 2023 |
| Sakura and Magnolia Blossoms Ltd | Real estate | 2025 |
| Sakura Sushi and Liquors Ltd | Hospitality | 2023 |
| Sales and Rooms Ltd | Real estate | 2025 |
| Salon.Eight Limited | Other services | 2017 |
| Salt Bliss Halotherapy Ltd | Health & social care | 2023 |
| Salvus Electrical Services Limited | Construction | 2015 |
| Sama Accounts Ltd | Professional & scientific | 2013 |
| Samatek Trading Company Ltd | Wholesale & retail | 2025 |
| Samcity Limited | Construction | 2024 |
| Samdocola Healthcare Services Limited | Health & social care | 2025 |
| Sangeeta Holdings Limited | Financial services | 2018 |
| Sangeeta Properties Limited | Real estate | 2016 |
| Sanman Cspt Ltd | Information & communication | 2024 |
| Sanman Ltd | Information & communication | 2012 |
| Sansat Infotech Limited | Information & communication | 2013 |
| Sanvi IT Solutions Limited | Information & communication | 2025 |
| SAO Strategy Ltd | Professional & scientific | 2025 |
| Sapharmco Limited | Professional & scientific | 2014 |
| Saphir Ltd | Other services | 2024 |
| Sarai Logistics (UK ) Ltd | Transport & logistics | 2023 |
| Saralucyhomes Ltd | Real estate | 2024 |
| Saralucyhomes Management Ltd | Real estate | 2025 |
| Sarang Events Ltd | Hospitality | 2022 |
| Saransh UK Limited | Information & communication | 2024 |
| Sardesai Property Ltd | Real estate | 2020 |
| Sarex Management Limited | Administrative & support | 2024 |
| Sarkz Ltd | Real estate | 2024 |
| Sasinfo.Ai Limited | Information & communication | 2025 |
| Satellite Television Services Ltd | Information & communication | 2022 |
| Save Payments & Tech Solutions Limited | Information & communication | 2026 |
| Save the Schools | Education | 2010 |
| Savvy Alarms Security Ltd | Construction | 2022 |
| Sawaddee Entertainment Ltd | Arts & recreation | 2025 |
| SB Land Development Ltd | Construction | 2025 |
| Sbpodcast Limited | Information & communication | 2025 |
| SBS Investment Properties Limited | Real estate | 2023 |
| Scandi Home Stagers Ltd | Professional & scientific | 2025 |
| SCD Carpentry Ltd | Manufacturing | 2023 |
| School Backed Commerce Ltd | Other services | 2023 |
| SCM IT Consultancy Ltd | Information & communication | 2015 |
| Sculpt Savvy Limited | Information & communication | 2024 |
| Scylla Labs Limited | Professional & scientific | 2025 |
| SDR Brothers Ltd | Hospitality | 2021 |
| SE Blue Builder Ltd | Construction | 2023 |
| SE London Property Management Limited | Real estate | 2023 |
| Seam Accountancy Ltd | Professional & scientific | 2021 |
| Seasons (Four) Ltd | Wholesale & retail | 2018 |
| Sebastien Chiono Ltd | Hospitality | 2025 |
| Sece Limited | Real estate | 2015 |
| Second Sight OO Limited | Wholesale & retail | 2026 |
| Seed First CIC | Agriculture & fishing | 2023 |
| Sefas TTB Ltd | Other services | 2025 |
| Sellier Investment Ltd | Real estate | 2024 |
| Selwyn Properties Limited | Real estate | 2020 |
| SEM Extra Ltd | Real estate | 2022 |
| Semper Agent Limited | Information & communication | 2026 |
| Sempreverde Limited | Health & social care | 2021 |
| Sentinelguard Security Services Limited | Administrative & support | 2024 |
| Sera Property Ltd | Real estate | 2021 |
| Serene Touch Cremations Ltd | Other services | 2019 |
| Serenity Supported Living Ltd | Health & social care | 2020 |
| Service Perfect Limited | Other services | 2015 |
| Setpoint Refrigeration Ltd | Manufacturing | 2018 |
| Seymour Sports Group Ltd | Arts & recreation | 2023 |
| SGR Accountancy Ltd | Professional & scientific | 2021 |
| SGS Limited Ltd | Hospitality | 2024 |
| SH Plus Co Ltd | Wholesale & retail | 2019 |
| Shaal Limited | Education | 2020 |
| Shai Properties Ltd | Real estate | 2020 |
| Shair Dental & Facial Care Ltd | Health & social care | 2021 |
| Shakthy & SON Ltd | Construction | 2022 |
| Shakti Homes Ltd | Real estate | 2025 |
| Shampan Welling Ltd | Hospitality | 2023 |
| Shan Ventures Limited | Health & social care | 2024 |
| Shannon Paige Aesthetics Limited | Health & social care | 2025 |
| Sharnbrooke Court Management Limited | Households | 1976 |
| Sharp Sports Management Ltd | Professional & scientific | 2024 |
| Sheena Vadukul Limited | Other services | 2021 |
| Shelby Aesthetics Ltd | Other services | 2023 |
| Shera Global Ltd | Professional & scientific | 2025 |
| Sherade Ltd | Administrative & support | 2021 |
| Sheree Botanica Ltd | Wholesale & retail | 2024 |
| Shining Heroes Ltd | Households | 2025 |
| Shippam Services Limited | Construction | 2024 |
| Shmily Limited | Wholesale & retail | 2011 |
| Shop Bridge PVT Ltd | Wholesale & retail | 2026 |
| Short Content Ltd | Information & communication | 2021 |
| Showline Collective Ltd | Other services | 2025 |
| Shreehari Developments Limited | Real estate | 2020 |
| Shreehari Tech Solutions Ltd | Information & communication | 2026 |
| Shreeji Cash & Carry Limited | Wholesale & retail | 2023 |
| Shri Maruti Properties Ltd | Real estate | 2026 |
| Shridasai Limited | Information & communication | 2019 |
| Shueae Alsharq Liltijarat Walastithmar Ltd | Wholesale & retail | 2025 |
| Shwet Prime Ltd | Wholesale & retail | 2026 |
| Sichuan Chef Limited | Real estate | 2020 |
| Siddhi Tech Ltd | Information & communication | 2021 |