| Saivize Consulting Limited | Information & communication | 2021 |
| SAK Medical Limited | Health & social care | 2013 |
| SAK Properties Limited | Real estate | 2015 |
| Sakinah Collections Ltd | Real estate | 2026 |
| Sakisiya Infra Ltd | Real estate | 2025 |
| Sakoon Resourcing Ltd | Other services | 2011 |
| Saksamadjnt Ltd | Wholesale & retail | 2026 |
| Sakura Auto Imports Ltd | Wholesale & retail | 2025 |
| SAL Digital Ltd | Information & communication | 2021 |
| Sala Advisory Ltd | Administrative & support | 2026 |
| Salaam Media Limited | Information & communication | 2025 |
| Salaar Associates Ltd | Wholesale & retail | 2026 |
| Saladq Group Limited | Information & communication | 2022 |
| Salasel Express Limited | Transport & logistics | 2023 |
| Salepush Trade Ltd | Wholesale & retail | 2022 |
| Salesdirects Online Limited | Wholesale & retail | 2019 |
| Salisbury House Residents' Association Limited | Administrative & support | 1984 |
| Sallisburd Limited | Information & communication | 2022 |
| Sallust Limited | Professional & scientific | 2020 |
| Sally Jane Hobson Property Ltd | Real estate | 2024 |
| Salmon Finance 1 Limited | Professional & scientific | 1954 |
| Salmon Finance 2 Limited | Professional & scientific | 1958 |
| Salmon Finance 3 Limited | Professional & scientific | 1949 |
| Salmon Management and Finance Limited | Financial services | 1949 |
| Salsal Services Limited | Information & communication | 2018 |
| Salt Developments Ltd | Construction | 2023 |
| Salt for My Squid Ltd | Professional & scientific | 2020 |
| Saltillo Ltd | Information & communication | 2009 |
| SAM Homes & Construction Limited | Construction | 2026 |
| SAM K&B Construction Ltd | Construction | 2023 |
| SAM Myer Consultancy Ltd | Information & communication | 2010 |
| SAM Star Enterprise Ltd | Information & communication | 2022 |
| Sam's HR Consultants Ltd | Administrative & support | 2017 |
| Sama Healthcare Limited | Transport & logistics | 2018 |
| Samah Beauty Limited | Other services | 2022 |
| Samarasimha Reddy Limited | Other services | 2025 |
| SAMARIUM62 Investments Limited | Real estate | 2016 |
| Samarth Solutions Limited | Information & communication | 2025 |
| Samatax Ltd | Transport & logistics | 2024 |
| Sambrook Court Freehold Account Limited | Real estate | 2016 |
| Sambrook Court Residents Management Company Limited | Households | 2005 |
| Sameer Enterprises Ltd | Real estate | 2022 |
| Sameer International Foods Ltd | Wholesale & retail | 2025 |
| Sameer Investments Ltd | Real estate | 2025 |
| Sameera Properties Limited | Real estate | 2018 |
| Samganak Ltd | Information & communication | 2019 |
| Samlynx Services Ltd | Health & social care | 2019 |
| Sammi MAY Hair & Beauty Ltd | Other services | 2022 |
| Samp Kenya Limited | Real estate | 2020 |
| Sampson Finance Limited | Financial services | 1998 |
| Samuel Elliott & Sons Limited | Professional & scientific | 1939 |
| Samuel Hodson Limited | Professional & scientific | 2023 |
| Samuel Smith Limited | Information & communication | 2010 |
| Samusoft Limited | Information & communication | 2014 |
| Samvam Enterprise Ltd | Wholesale & retail | 2026 |
| SAN Caine Ltd | Professional & scientific | 2013 |
| SAN Property Services Limited | Real estate | 2021 |
| Sana Bookkeeping Services Ltd | Professional & scientific | 2014 |
| Sanastech Limited | Wholesale & retail | 2024 |
| Sanctuary Art of Sound Ltd | Information & communication | 2005 |
| Sandalwood Property Management Limited | Households | 2020 |
| Sandbar Consultants Limited | Professional & scientific | 2022 |
| Sanderson Select Limited | Other services | 2001 |
| Sandess Water Hygiene Services Limited | Manufacturing | 1989 |
| Sandfox Consulting Ltd | Professional & scientific | 2021 |
| Sando Accounting Limited | Professional & scientific | 2015 |
| Sandringham Court Residents Company Limited | Households | 1988 |
| Sandringham Gate (Ruislip) Management Company Limited | Households | 2009 |
| Sands END Consulting Ltd | Information & communication | 2014 |
| Sandy River Heights Limited | Information & communication | 2016 |
| Sangiev Limited | Information & communication | 2017 |
| Sann Builders Ltd | Construction | 2019 |
| Sann Investments Ltd | Real estate | 2018 |
| Sanraj Property Holdings Limited | Real estate | 2024 |
| Sanraj Property Investments Ltd | Real estate | 2006 |
| Sanraj Property UK Limited | Real estate | 2024 |
| Sans Trading Limited | Wholesale & retail | 2020 |
| Sansetive Food Centre Ltd | Wholesale & retail | 2020 |
| Sansho Consulting Ltd | Information & communication | 2015 |
| Santarch Properties Ltd | Real estate | 2019 |
| Sanvest Holdings Limited | Financial services | 2025 |
| Sanvi Supply Ltd | Wholesale & retail | 2021 |
| Saola Media Ltd | Administrative & support | 2025 |
| SAP Plant Maintenance Solutions Limited | Information & communication | 2026 |
| SAP Pro Limited | Information & communication | 2007 |
| Sapna Vyuha Ltd | Information & communication | 2024 |
| SAR Hospitality Ltd | Hospitality | 2024 |
| Sarah a Moss Consulting Solutions Ltd. | Professional & scientific | 2005 |
| Sarah Catherine Ltd | Administrative & support | 2023 |
| Sarah Hampson Design Ltd | Professional & scientific | 2018 |
| Sarah's Home Care Ltd | Health & social care | 2016 |
| Sarakoms Limited | Health & social care | 2013 |
| Sargeson Limited | Administrative & support | 2011 |
| Sarimsaeed Ltd | Wholesale & retail | 2025 |
| Sarita's Restaurant Limited | Hospitality | 2002 |
| Sariz Invest Ltd | Real estate | 2016 |
| Sarq Pharma Ltd | Professional & scientific | 2016 |
| Sars Electrical Limited | Construction | 2025 |
| Sarveshwar Consultancy Limited | Information & communication | 2017 |
| Sasate Ltd | Professional & scientific | 2014 |