| S. Howard Carpentry Ltd. | Construction | 2018 |
| S.A.W. Manufacturing Ltd | Real estate | 2021 |
| S.C.G. Construction Limited | Construction | 2007 |
| S.C.O LEV Ltd | Real estate | 2018 |
| S.Dell & Son(Investments)Limited | Construction | 1964 |
| S.E.S. (Engine Services) Limited | Real estate | 1977 |
| S.E.W. Consulting Limited | Professional & scientific | 2007 |
| S.F.G Transports Limited | Transport & logistics | 2026 |
| S.G William Construction Ltd | Construction | 2022 |
| S.G.C. Scaffolding Limited | Construction | 1993 |
| S.G.E. North London Limited | Construction | 2002 |
| S.J.C. Associates Limited | Professional & scientific | 2000 |
| S.K. Accountancy Services Limited | Professional & scientific | 1997 |
| S.L.M.A Investments Ltd | Real estate | 2023 |
| S.M.R. Engineering Services Limited | Manufacturing | 2017 |
| S.Mistry GAS & Electric Ltd | Construction | 2009 |
| S.Swidzinska Ltd | Hospitality | 2025 |
| S.T.Andrews Contractors Limited | Construction | 2022 |
| S1AUTOREPAIRS Ltd | Professional & scientific | 2026 |
| S2M Ventures LLP | | 2013 |
| S2R Solutions Limited | Information & communication | 2018 |
| S54 Engineering Ltd | Wholesale & retail | 2024 |
| SA Law LLP | | 2005 |
| SA Law Solicitors Limited | Professional & scientific | 2010 |
| SA Sparks Electrical Services Ltd | Construction | 2024 |
| SA Training Centre Ltd | Education | 2022 |
| SA Wellbeing Ltd | Health & social care | 2017 |
| SA9 Groups UK Ltd | Manufacturing | 2025 |
| SAA Builder Ltd | Construction | 2023 |
| SAA Procurement Solutions Limited | Information & communication | 2008 |
| Saal Digital UK Limited | Wholesale & retail | 2020 |
| Saath Properties Ltd | Real estate | 2022 |
| Saattvik Ltd | Professional & scientific | 2012 |
| Saba Group UK Limited | Financial services | 2018 |
| Saba Infra Cambridgeshire Limited | Transport & logistics | 2012 |
| Saba Infra Gloucestershire Limited | Transport & logistics | 2009 |
| Saba Infra Hertfordshire Limited | Transport & logistics | 2010 |
| Saba Infra Holdings UK Limited | Professional & scientific | 1991 |
| Saba Infra Liverpool Limited | Transport & logistics | 2018 |
| Saba Infra UK Limited | Transport & logistics | 1995 |
| Saba Park Services UK Limited | Transport & logistics | 1989 |
| Saba Park Solutions UK Limited | Transport & logistics | 1990 |
| Saba Unigarage UK Limited | Transport & logistics | 1995 |
| Sabat Accountants Ltd | Professional & scientific | 2019 |
| Sabio Solutions Limited | Professional & scientific | 2018 |
| Sabr Scents Ltd | Wholesale & retail | 2025 |
| Sabra Hospitality Management Limited | Administrative & support | 2020 |
| Sabresul Ltd | Real estate | 2024 |
| Sabtech Consulting Limited | Information & communication | 2012 |
| Sach Mohan Limited | Health & social care | 2006 |
| Sacred Heart Health Care Ltd | Health & social care | 2015 |
| Sadguru OM Consultancy Limited | Information & communication | 2013 |
| Sadi IT Consultancy Ltd | Information & communication | 2025 |
| Sadies Home Decor Ltd | Wholesale & retail | 2019 |
| Safa Corporate Services Ltd | Administrative & support | 2023 |
| Safah Rentals Ltd | Wholesale & retail | 2023 |
| Safan Property Group Ltd | Construction | 2024 |
| Safari Adventures Ltd | Administrative & support | 2025 |
| Safe Circuit Limited | Construction | 2017 |
| Safe House Maintenance Services Limited | Construction | 2019 |
| Safe Plumbing&Gas Engineers Ltd | Manufacturing | 2019 |
| Safe Transactions Ltd | Information & communication | 2024 |
| Safecare Health Services Ltd | Health & social care | 2017 |
| Safeena Holdings Ltd | Financial services | 2024 |
| Safeguard Investments Ltd | Real estate | 2024 |
| Safer Streets Team & Events CIC | Public administration | 2022 |
| Safeslab Limited | Extraterritorial | 2013 |
| Safetech Asbestos Ltd | Construction | 2026 |
| Saffron Cosmetics Limited | Wholesale & retail | 2022 |
| Saffron Dining House Ltd | Hospitality | 2026 |
| Saffron Networks Ltd | Information & communication | 2006 |
| Saffron Pharma Consulting Ltd | Professional & scientific | 2014 |
| Saffron Property (Aylesbury) Limited | Real estate | 2015 |
| Saflo Limited | Wholesale & retail | 2022 |
| Sagar Consultants (UK) Ltd | Education | 2012 |
| Sagar Estates Ltd | Real estate | 2023 |
| Sage Elegante Ltd | Professional & scientific | 2023 |
| Sageeai Ltd | Information & communication | 2025 |
| Sahaj Ltd | Wholesale & retail | 2016 |
| Sahajomi Limited | Health & social care | 2019 |
| Sahara Ventures Limited | Real estate | 1998 |
| Sahbye Consultancy Limited | Professional & scientific | 2018 |
| Sahil 'S Mediation Services Ltd | Other services | 2023 |
| Sahota Financial Consulting Ltd | Financial services | 2023 |
| SAI Automate M Limited | Professional & scientific | 2025 |
| SAI DRS Limited | Energy | 2025 |
| SAI Miyan Limited | Wholesale & retail | 2021 |
| Saiesh Investment Ltd | Extraterritorial | 2009 |
| Sail Freeholds Limited | Real estate | 2019 |
| Sainath Krupa Limited | Transport & logistics | 2025 |
| Sainek Ltd | Transport & logistics | 2017 |
| Saini Legal Limited | Professional & scientific | 2010 |
| Saint Blue Seven Ltd | Professional & scientific | 2018 |
| Saint Leonard Veterinary Centre Limited | Professional & scientific | 2013 |
| Saintgold Limited | Information & communication | 2012 |
| Saiprema Holdings Ltd | Real estate | 2025 |
| Sairam Traders Ltd | Wholesale & retail | 2020 |
| Saishay Limited | Wholesale & retail | 2025 |
| Saisree Solutions Ltd | Information & communication | 2016 |
| Saistuti Holdings Limited | Financial services | 2013 |