| Stealth Accountancy Services Limited | Professional & scientific | 2010 |
| Stealth Bookkeeping Services Limited | Professional & scientific | 2010 |
| Steane Limited | Construction | 1979 |
| Steenssen Limited | Manufacturing | 2013 |
| Stellar Luxé Property Ltd | Real estate | 2025 |
| Stemsation UK Limited | Wholesale & retail | 2019 |
| Stephen Quigley and Sons Limited | Wholesale & retail | 2008 |
| Stereomatic Holdings Limited | Real estate | 2024 |
| Sterling Recruitment Solutions Limited | Construction | 2010 |
| Sterling Site Services Limited | Construction | 2020 |
| Stet Properties Limited | Real estate | 2025 |
| Steve Haynes Forestry Services Ltd | Agriculture & fishing | 2018 |
| Steve Webb Communications Limited | Information & communication | 2023 |
| Steve Williamson Air Traffic Managment Solutions Limited | Professional & scientific | 2017 |
| Steve XM Mods Limited | Information & communication | 2025 |
| Stewart and Jason Feenan Electrical and Building Specialists Ltd | Construction | 2023 |
| Stez Limited | Administrative & support | 2012 |
| Stichd Sportmerchandising UK Ltd | Wholesale & retail | 2007 |
| Stickleback Enterprises Limited | Information & communication | 2013 |
| Stickleback Technologies Limited | Information & communication | 2014 |
| Stid Electronic Identification Limited | Wholesale & retail | 2013 |
| Still Point Psychotherapy Ltd | Health & social care | 2017 |
| Stipenda Administration Ltd | Administrative & support | 2018 |
| Stipenda Employment Ltd | Administrative & support | 2018 |
| Stipenda Limited | Administrative & support | 2018 |
| Stitch Happy Ltd | Wholesale & retail | 2021 |
| Stoli Catalysts Ltd | Manufacturing | 2016 |
| Stolpe Publishing Ltd | Information & communication | 2021 |
| Stolutions Ltd | Professional & scientific | 2012 |
| Stolutions Property Ltd | Real estate | 2020 |
| Stoneleigh Builders Ltd | Construction | 2020 |
| Stoneleigh Gardens Management Company Limited | Households | 2022 |
| Stoneleigh Gardens SPV Limited | Real estate | 2021 |
| Stonewell Design & Build Limited | Construction | 2009 |
| Storebase Limited | Transport & logistics | 2014 |
| STR8 4WARD Solutions Ltd | Information & communication | 2003 |
| Strak Concept Limited | Professional & scientific | 2016 |
| Strategic Counsel Limited | Professional & scientific | 2012 |
| Stratford Playhouse Community Theatre CIC | Arts & recreation | 2025 |
| Stratford Plumbing & Heating Ltd | Construction | 2018 |
| Stratwicks Limited | Wholesale & retail | 1984 |
| Strawberry Developments Limited | Construction | 2002 |
| Streetsbrook Road (Solihull) Management Limited | Households | 2004 |
| Stride Clinics Ltd | Health & social care | 2021 |
| STRIVE4IT Limited | Information & communication | 2022 |
| Strofac Limited | Hospitality | 2021 |
| Stronger Support Ltd | Health & social care | 2025 |
| Strumin UK Limited | Wholesale & retail | 2025 |
| STS Great Britain Limited | Wholesale & retail | 2008 |
| Stuart Chalmers GAS and Heating Limited | Professional & scientific | 2023 |
| Studio 23 Records Ltd | Information & communication | 2026 |
| Studio 92 Ltd | Professional & scientific | 2024 |
| Studio Mikael Jansson Limited | Professional & scientific | 2015 |
| Studio Pixels Limited | Extraterritorial | 2008 |
| Studio RK Limited | Information & communication | 2025 |
| Studio SIX (1992) Limited | Real estate | 1992 |
| Studio SIX Investments Ltd | Real estate | 2024 |
| STW Digital Ltd | Professional & scientific | 2017 |
| Style & Smile Hair and Beauty Ltd | Other services | 2024 |
| Stylishgolf Limited | Information & communication | 2019 |
| SU YAN Medical Aesthetics Limited | Other services | 2023 |
| Subport (South Mids) Ltd | Professional & scientific | 2021 |
| Substation Commissioning Services Ltd | Manufacturing | 2012 |
| Success Engineers Limited | Administrative & support | 2017 |
| Sudha Real Estate Ltd | Real estate | 2024 |
| SUE Shortland Ltd | Professional & scientific | 2025 |
| Suman Investment Properties Limited | Real estate | 2023 |
| Summa Equity Advisory Ltd. | Financial services | 2024 |
| Summa Equity Advisory UK LLP | | 2024 |
| Summitgrowth.Io Limited | Professional & scientific | 2025 |
| Sunborn Energy Limited | Administrative & support | 2022 |
| Sunborn Evolution Ltd | Wholesale & retail | 2024 |
| Sunborn International (UK) Limited | Hospitality | 1999 |
| Suncomms 5G Ltd | Information & communication | 2020 |
| Suncomms Consulting Limited | Information & communication | 2013 |
| Sunfab UK Limited | Administrative & support | 2010 |
| Sunnier Dayz Ltd | Professional & scientific | 2021 |
| Sunrise Coffee & Bakery Ltd | Hospitality | 2025 |
| Sunrise Coffee (Warwick) Ltd | Hospitality | 2024 |
| Sunrise Coffee Solutions Ltd | Wholesale & retail | 2025 |
| Suns OUT Guns OUT Limited | Administrative & support | 2025 |
| Sunset Views (New Forest) Limited | Administrative & support | 2023 |
| Superpea Ltd. | Information & communication | 2011 |
| Supersonic Playground Ltd | Information & communication | 2014 |
| Support Comms Limited | Manufacturing | 2001 |
| Supra Limited | Information & communication | 1998 |
| Supreme Coffee Trading Company Limited | Wholesale & retail | 2020 |
| Supreme Sports Tax Ltd | Professional & scientific | 2023 |
| Supremeware Limited | Information & communication | 2015 |
| Sure Footed Ltd | Health & social care | 2014 |
| Sureeporn Investment Ltd | Real estate | 2025 |
| Surfreset Limited | Financial services | 1999 |
| Surgery in Motion Limited | Extraterritorial | 2008 |
| Susan Davis Garden Design Ltd | Administrative & support | 2026 |
| Sustainable Engagement Ltd | Professional & scientific | 2024 |
| Sustainable Investment Solutions UK Limited | Professional & scientific | 2018 |
| Swale Motors Limited | Financial services | 1946 |
| Swallow Machinery Limited | Wholesale & retail | 1989 |
| Swart Simoes RCF Ltd | Professional & scientific | 2020 |
| SWC Management Services Limited | Professional & scientific | 1995 |