| Social Infinity Limited | Professional & scientific | 2022 |
| Social Tech Limited | Extraterritorial | 2019 |
| Social Unity Media Ltd | Professional & scientific | 2019 |
| Sodi-Tech EDM Limited | Wholesale & retail | 1991 |
| Sodick Europe Holdings Limited | Wholesale & retail | 2002 |
| Sodick Europe Limited | Manufacturing | 2000 |
| Sodick Used Machines Limited | Extraterritorial | 2000 |
| Soeurs Jewellery Limited | Manufacturing | 2021 |
| Soft-Focus Productions Limited | Information & communication | 2011 |
| Softtech Consultants Limited | Information & communication | 2019 |
| Softvigil Limited | Information & communication | 2000 |
| Soho Fine Art Limited | Wholesale & retail | 2021 |
| Soho Gallery Limited | Wholesale & retail | 2021 |
| Solartech ESS Ltd | Construction | 2025 |
| Solas Europe UK Limited | Wholesale & retail | 2022 |
| Solidlox Limited | Construction | 2011 |
| Solidus Labs Ltd | Information & communication | 2021 |
| Solutions UK (IG) Limited | Wholesale & retail | 2019 |
| Solutionsonsite Ltd | Information & communication | 2023 |
| Sommalife Limited | Information & communication | 2024 |
| SON of a Nerd Ltd | Wholesale & retail | 2026 |
| Sonil Consultants Ltd | Administrative & support | 2012 |
| Sonil Property Holdings Limited | Real estate | 2020 |
| Soorly Associates Limited | Health & social care | 2025 |
| Sophie Bille Brahe Ltd | Manufacturing | 2025 |
| Sorbit Ltd | Education | 2025 |
| Sorrell Decorators Limited | Construction | 2012 |
| Soundtrack Technologies UK Limited | Information & communication | 2024 |
| Soundtrap Limited | Information & communication | 2023 |
| Soup Music Limited | Information & communication | 2009 |
| South African Secrets Limited | Administrative & support | 2012 |
| South Warwickshire Construction Limited | Construction | 2008 |
| South Warwickshire School of Flying Limited | Other services | 1998 |
| Southern Hemisphere Steels Limited | Wholesale & retail | 1993 |
| Southlock Limited | Administrative & support | 2019 |
| Southwest House Ltd | Hospitality | 2023 |
| Soutter Support Ltd | Manufacturing | 2022 |
| SP Simtech Ltd | Hospitality | 2023 |
| Spa Business Services (LSO) Limited | Information & communication | 2023 |
| Spa Electrical Services Ltd | Construction | 2022 |
| Spa Electrical Solutions Ltd | Construction | 2026 |
| Spa Property Maintenance Limited | Construction | 2022 |
| Spa Strategy Associates Limited | Professional & scientific | 2015 |
| Spa Town Marketing Ltd | Professional & scientific | 2023 |
| Space Engine Systems Limited | Manufacturing | 2021 |
| Spaleam Limited | Extraterritorial | 1951 |
| Sparkes Limited | Administrative & support | 2003 |
| Sparkes Will FLY Limited | Manufacturing | 2015 |
| Sparksmaths Ltd | Professional & scientific | 2023 |
| Special Environments Medical Group Ltd | Health & social care | 2025 |
| Specialist Social Care Assessments Ltd | Health & social care | 2024 |
| Specna Distribution UK Limited | Wholesale & retail | 2023 |
| Spectacular Goat Limited | Hospitality | 2014 |
| Speech Therapy Warwickshire Ltd | Health & social care | 2013 |
| Speed Octane UK Ltd | Wholesale & retail | 2020 |
| Spelgora Limited | Information & communication | 2025 |
| Spicing Club Limited | Hospitality | 2025 |
| Spillage AH Ltd | Hospitality | 2026 |
| Spillage ALE Houses Ltd | Hospitality | 2024 |
| Spires Technologies Ltd | Wholesale & retail | 2008 |
| Sponge Hammer Games Limited | Information & communication | 2018 |
| Spoon & Whisk Ltd | Manufacturing | 2020 |
| Spoorthi Solutions Limited | Information & communication | 2016 |
| Spotless Detailing Limited | Administrative & support | 2014 |
| Spring Peak Property Limited | Real estate | 2026 |
| Springback Binders Limited | Manufacturing | 2003 |
| Springfresh Foods Limited | Hospitality | 2003 |
| Springworth (Building & Interiors) Limited | Construction | 2005 |
| Spurstowe Terrace Limited | Real estate | 2015 |
| SPY Games Limited | Other services | 2019 |
| Spyscape Ltd | Information & communication | 2016 |
| Squires Restaurant and Bar Ltd | Hospitality | 2017 |
| Squirrels Field Ltd | Financial services | 2023 |
| Sras Management Limited | Professional & scientific | 2025 |
| Srika UK Lanka Ltd | Wholesale & retail | 2021 |
| Sriven Consulting Services UK Ltd | Information & communication | 2013 |
| SRM Electrical Limited | Manufacturing | 1998 |
| Srrec Ltd | Real estate | 2026 |
| SS Educoaching Ltd | Education | 2026 |
| SS Technical Services Limited | Professional & scientific | 2013 |
| Sscw Holdings Limited | Financial services | 2024 |
| ST Ann's Court Management Limited | Administrative & support | 1986 |
| ST Dennis Family Investments | Financial services | 2024 |
| ST Johns Barbers Limited | Other services | 2015 |
| ST Nicholas Financial Services Ltd | Professional & scientific | 2017 |
| ST. Chill Associates Ltd | Other services | 2023 |
| ST. George's Court (Sutton Coldfield) Limited | Households | 1988 |
| St.Dub Engineering Limited | Administrative & support | 2009 |
| Staak Studio Limited | Information & communication | 2020 |
| Stable Drive Management Company Limited | Households | 2006 |
| Stableoak (Oxhill) Management Company Limited | Real estate | 2018 |
| Stacey Lloyd Teaching Ltd | Wholesale & retail | 2021 |
| Stampa Digital Limited | Information & communication | 2020 |
| Stanila Properties Ltd | Real estate | 2022 |
| Stanley House Consulting Limited | Administrative & support | 2022 |
| Staple Hill House Limited | Households | 1997 |
| Star*Struck Promotions Ltd | Arts & recreation | 2022 |
| Stardust Entertainment Group Ltd | Professional & scientific | 2022 |
| Starshine Ltd | Real estate | 2023 |
| Start Architecture Ltd | Professional & scientific | 2016 |