| Emnell Apparel Ltd | Wholesale & retail | 2024 |
| Emniyet Engineering Ltd | Administrative & support | 2021 |
| Emotional Wellbeing Group Ltd | Health & social care | 2020 |
| EMP Developments Ltd | Real estate | 2003 |
| Empedrola Trading Company Limited | Professional & scientific | 2022 |
| Empira Ltd | Professional & scientific | 2021 |
| Empire Dealz Ltd | Professional & scientific | 2025 |
| Empire Events Warrington Limited | Hospitality | 2025 |
| Empire Property Innovation Ltd | Real estate | 2020 |
| Employee Management Ltd | Professional & scientific | 1986 |
| Empower Educational Services Ltd | Education | 2026 |
| Empower Service Solutions Ltd | Professional & scientific | 2025 |
| EMR Exports Limited | Extraterritorial | 1997 |
| EMR Group Dormant Subs Limited | Professional & scientific | 2006 |
| EMR Group Limited | Water & waste | 1994 |
| EMR Group Other Subs Limited | Professional & scientific | 2006 |
| EMR Midland Shredders Limited | Extraterritorial | 1971 |
| EMR Polymers Limited | Manufacturing | 2007 |
| EMR Reusable Steels Limited | Manufacturing | 2023 |
| EMR Shipping Limited | Professional & scientific | 1985 |
| EMR USA Holdings Limited | Professional & scientific | 2006 |
| EMS24/7 Ltd | Education | 2025 |
| Emson CAD Ltd | Administrative & support | 2026 |
| Emtec Climate Solutions Limited | Manufacturing | 2015 |
| Emtex Consultancy Ltd | Professional & scientific | 2025 |
| Emvision Limited | Other services | 2017 |
| Enabling Connections Ltd | Wholesale & retail | 2023 |
| ENC Technical Search Limited | Administrative & support | 2026 |
| Encore FM Limited | Professional & scientific | 2019 |
| END-2-END Screening Ltd | Health & social care | 2025 |
| Endar Consulting Ltd | Professional & scientific | 2019 |
| Endeavour Plant Holdings Limited | Professional & scientific | 2019 |
| Endeavour Plant Limited | Administrative & support | 2013 |
| Endeavour Project Services Limited | Professional & scientific | 2018 |
| Endicon Limited | Professional & scientific | 2025 |
| Endo Enterprises (UK) Limited | Manufacturing | 2013 |
| Endobyshanil Limited | Health & social care | 2023 |
| Endov Consulting Ltd | Professional & scientific | 2024 |
| Endovision Ltd | Health & social care | 2023 |
| Enduro Logistics Ltd | Transport & logistics | 2020 |
| ENE Developments Ltd | Construction | 2023 |
| ENE Property Developments Ltd | Construction | 2024 |
| Energec Group Ltd | Construction | 2019 |
| Energel Limited | Construction | 2006 |
| Energethical Limited | Professional & scientific | 2023 |
| Energies CSS Limited | Administrative & support | 2024 |
| Energiestor Ltd | Manufacturing | 2019 |
| Energitech Ltd | Construction | 2007 |
| Energize Capital (NO. 1) Limited | Financial services | 2025 |
| Energize Capital Limited | Financial services | 2009 |
| Energize Capital Partners LLP | | 2009 |
| Energy 75 Consult Ltd | Administrative & support | 2022 |
| Energy Advisory Partners Ltd | Professional & scientific | 2019 |
| Energy Ombudsman Limited | Professional & scientific | 2022 |
| Energy Trading Advisory Ltd | Administrative & support | 2020 |
| Energy Water International Ltd | Administrative & support | 2020 |
| Energy Within Ltd | Health & social care | 2024 |
| Energy Works Ltd | Administrative & support | 2023 |
| Energy, Safety and Risk Consultants (UK) Limited | Professional & scientific | 2011 |
| Energy, Security and Technology UK Limited | Professional & scientific | 2024 |
| Enerhex Ltd | Administrative & support | 2023 |
| Enfatek Ltd | Wholesale & retail | 2025 |
| ENG Tech Assure Ltd | Professional & scientific | 2023 |
| Eng-Assure Limited | Administrative & support | 2008 |
| Engage 5 Ltd | Professional & scientific | 2022 |
| Engage HR Services Ltd | Administrative & support | 2024 |
| Engage Mortgage Solutions Ltd | Financial services | 2016 |
| Engage Productions Ltd | Arts & recreation | 2018 |
| Engaged Canine Services Ltd | Other services | 2025 |
| Engdev Ltd | Professional & scientific | 2014 |
| Engineering & Programme Management Limited | Transport & logistics | 2015 |
| Engineering & Project Management Consultants Ltd | Professional & scientific | 2019 |
| Engineering and Exploration Services Ltd | Construction | 2019 |
| Engineering and Infrastructure Project Management Ltd | Professional & scientific | 2022 |
| Engineering Consultant Services Limited | Professional & scientific | 2017 |
| Engineering Excellence Limited | Administrative & support | 2013 |
| Engineering Management Systems Ltd | Professional & scientific | 2018 |
| Engineering Odyssey Ltd | Manufacturing | 2024 |
| Engineering Safety Inspection Services Limited | Professional & scientific | 1997 |
| Engineering Services & Home Solutions Ltd | Administrative & support | 2023 |
| Engineering Services Daniel Wilczynski Ltd | Administrative & support | 2024 |
| Engineering Success Ltd | Professional & scientific | 2014 |
| Engineering Surveyor Limited | Administrative & support | 2013 |
| Engineering Venture Limited | Administrative & support | 2012 |
| Enginuity Recruitment Ltd | Administrative & support | 2025 |
| English Karate Academy Limited | Arts & recreation | 2010 |
| Enhance Risk & Analytics Consulting Limited | Administrative & support | 2015 |
| Enigma Tech Solutions Ltd | Information & communication | 2025 |
| Eniyaa Ltd | Real estate | 2020 |
| Enjoy Coaching Ltd | Administrative & support | 2014 |
| Enjoy Football CIC | Other services | 2019 |
| Enjoy the Show Limited | Other services | 2018 |
| Ennay Tech Ltd | Administrative & support | 2022 |
| Enpower AI Ltd | Information & communication | 2023 |
| Enratec UK Limited | Professional & scientific | 2016 |
| Enrg Business Consultancy Ltd | Professional & scientific | 2019 |
| ENS Associates Limited | Information & communication | 2002 |
| Ensign Building Projects Limited | Construction | 2016 |
| Ensign Developments Limited | Construction | 2016 |
| Ensign Genesis Limited | Administrative & support | 2016 |