| Ryim Ltd | Professional & scientific | 2015 |
| Rylance Associates Limited | Administrative & support | 2015 |
| Rylands Recreation Club Limited | Education | 2016 |
| Rymes Solar Limited | Energy | 2011 |
| Ryse UP CIC | Other services | 2026 |
| Rytec Solutions Ltd | Administrative & support | 2007 |
| Rywood Estates Limited | Real estate | 2025 |
| RZ Consultancy Limited | Administrative & support | 2014 |
| S & a Tailored Repairs Limited | Administrative & support | 2016 |
| S & C Drain Services Ltd | Water & waste | 2019 |
| S & D Houses Ltd | Real estate | 2026 |
| S & D Living Ltd | Real estate | 2025 |
| S & E Jewellery Limited | Wholesale & retail | 2007 |
| S & E Property Rental Ltd | Real estate | 2025 |
| S & F Consultants Limited | Professional & scientific | 2017 |
| S & G Building and Property Improvements Limited | Construction | 2015 |
| S & K Properties (NW) Ltd | Real estate | 2023 |
| S & S Scaffolding Ltd | Administrative & support | 2019 |
| S Akram Limited | Administrative & support | 2013 |
| S Bayliss Procurement Ltd | Wholesale & retail | 2022 |
| S Bevan Hairdressing Limited | Other services | 2003 |
| S Brown Limited | Professional & scientific | 2016 |
| S D & H Sales Ltd | Manufacturing | 1981 |
| S Dass Limited | Administrative & support | 2024 |
| S Davey Consulting Limited | Administrative & support | 2008 |
| S Davies Safety Services Limited | Administrative & support | 2014 |
| S Denis Consulting Ltd | Administrative & support | 2022 |
| S Dent Consultancy Limited | Professional & scientific | 2022 |
| S E Walls Limited | Professional & scientific | 2019 |
| S F Craw Engineering Services Ltd | Professional & scientific | 2019 |
| S F Hill Consultancy Limited | Professional & scientific | 2018 |
| S G Bannister Engineering Ltd | Professional & scientific | 2023 |
| S H S Anderson Limited | Education | 2017 |
| S Iqbal Services Ltd | Manufacturing | 2026 |
| S J Barlow Ltd | Information & communication | 2011 |
| S J H Joinery & Windows Limited | Construction | 2009 |
| S J R Recovery Ltd | Transport & logistics | 2015 |
| S JAY Solutions Ltd | Information & communication | 1996 |
| S K Enviro Ltd | Manufacturing | 2015 |
| S Kandar Ltd | Other services | 2019 |
| S L Evans Ltd | Real estate | 2025 |
| S M Asset Recovery Ltd | Administrative & support | 2016 |
| S M Engineering Consultants Limited | Professional & scientific | 2021 |
| S M Hatcher Limited | Wholesale & retail | 2007 |
| S M Norman Accountancy Ltd | Professional & scientific | 2008 |
| S M Nuttall Limited | Professional & scientific | 2002 |
| S Miles Project Support Services Limited | Administrative & support | 2013 |
| S N Construction Services Limited | Professional & scientific | 2013 |
| S Omariba Ltd Ltd | Health & social care | 2025 |
| S P Dental Laboratory Ltd | Manufacturing | 2010 |
| S P G Hygiene Limited | Administrative & support | 2011 |
| S P Garratt Building Contractors Limited | Construction | 2007 |
| S Penhaligon Ltd | Professional & scientific | 2022 |
| S Rose Property Holdings Ltd | Real estate | 2025 |
| S Swiffen Ltd | Construction | 2022 |
| S W K Projects Limited | Administrative & support | 2016 |
| S Warburton Obsessive Car Detailing Ltd | Wholesale & retail | 2013 |
| S Watson Gynaecology Ltd | Professional & scientific | 2022 |
| S Yates Software Ltd | Information & communication | 2019 |
| S&C Leman Ltd | Professional & scientific | 2026 |
| S&G Property Management Ltd | Construction | 2019 |
| S&H K Properties Ltd | Real estate | 2022 |
| S&L Enterprises Limited | Other services | 2025 |
| S&N Rentals Northwest Ltd | Real estate | 2025 |
| S&P Engineering Ltd | Administrative & support | 2024 |
| S&R Property Solutions Ltd | Real estate | 2026 |
| S&Sh Property Limited | Real estate | 2019 |
| S'Watered Ltd | Manufacturing | 2024 |
| S. J. Redfern Design Ltd | Professional & scientific | 2020 |
| S. Keech Garden Maintenance Ltd | Water & waste | 2010 |
| S. Lucas Engineering Limited | Professional & scientific | 1985 |
| S. Wilkinson Drain Jetting Limited | Construction | 2005 |
| S.D. IT Consultancy Limited | Administrative & support | 2024 |
| S.D. Pare Carpet Contractors Limited | Construction | 2002 |
| S.E.E.O Consultants Ltd | Information & communication | 2019 |
| S.J. Riches Limited | Administrative & support | 2012 |
| S.M.W.Trading Ltd | Real estate | 2017 |
| S.P. Water Pumps Limited | Manufacturing | 1999 |
| S20 Business Solutions Limited | Other services | 2017 |
| S27 Electrical Services Ltd | Construction | 2013 |
| S3G Limited | Administrative & support | 2005 |
| S4 Strategic Solutions Ltd | Administrative & support | 2025 |
| S4U Limited | Information & communication | 2018 |
| S5 Design Ltd | Professional & scientific | 2023 |
| S85LEEHEALTHCARE Ltd | Health & social care | 2022 |
| SA Chefs and Kitchen Consultant Limited | Hospitality | 2020 |
| SA Coms DOT COM Ltd | Administrative & support | 2014 |
| SA Demolition Company Ltd | Construction | 2026 |
| SA OIL & GAS Consultancy Limited | Professional & scientific | 2017 |
| SA Performance Hull Ltd | Extraterritorial | 2021 |
| SA Project Science Limited | Professional & scientific | 2016 |
| SA Reardon Services Ltd | Administrative & support | 2022 |
| SAB Electrical Ltd | Administrative & support | 2019 |
| SAB G.I.A.C Limited | Administrative & support | 2016 |
| Saber Technical Solutions Limited | Administrative & support | 2026 |
| Sabita Consultancy Limited | Administrative & support | 2013 |
| Sabregreen Limited | Information & communication | 2009 |
| SAC Engineering Services Limited | Professional & scientific | 2017 |
| SAC Rail Limited | Construction | 2015 |
| Sach Holdings Limited | Construction | 2017 |