| DSL Loha Limited | Other services | 2023 |
| DSM Building & Construction Limited | Construction | 2025 |
| DSM Management (UK) Limited | Professional & scientific | 2007 |
| DSN Property Ltd | Real estate | 2022 |
| DSS Property Portfolio Ltd | Real estate | 2021 |
| DSW Training Ltd | Education | 2024 |
| DT Maintenance Ltd | Construction | 2019 |
| DT Trade Ltd | Wholesale & retail | 2025 |
| DTL Logistics Ltd | Transport & logistics | 2017 |
| DTM Estates Ltd | Real estate | 2025 |
| Dtm.Construction Ltd | Construction | 2023 |
| Dtox Postbiotics Ltd | Wholesale & retail | 2025 |
| Dtsg Limited | Manufacturing | 2013 |
| DTV Band LLP | | 2021 |
| Dubai Life Ltd | Other services | 2018 |
| Dubb Group Limited | Real estate | 2023 |
| Ducci Digital Limited | Information & communication | 2025 |
| Ductbusters Ductwork Limited | Construction | 2010 |
| Dudley Contractors Limited | Construction | 2014 |
| Dudley Fields Motors Ltd | Wholesale & retail | 2016 |
| Dulai Properties Ltd | Real estate | 2015 |
| Duneth Securities Limited | Construction | 1905 |
| Dunfold Limited | Wholesale & retail | 1998 |
| Dunley Hall Limited | Health & social care | 2012 |
| Dunn Leaking Ltd | Construction | 2022 |
| Dunton Environmental Limited | Water & waste | 2006 |
| Dunton Technologies Limited | Water & waste | 2014 |
| DUO Electrical Limited | Construction | 2013 |
| Dupatta Ltd | Wholesale & retail | 2026 |
| Duraclean Solutions Ltd | Administrative & support | 2026 |
| Durrani Wholesalers Ltd | Wholesale & retail | 2025 |
| Durwen (UK) Limited | Wholesale & retail | 2010 |
| Dust Buster Cleaning Services Ltd | Administrative & support | 2016 |
| Dutchman International Limited | Wholesale & retail | 2023 |
| Duxt Ltd | Information & communication | 2025 |
| Dwelan Property Limited | Real estate | 2024 |
| DWR Technology Limited | Information & communication | 2002 |
| DWS Building & Mechanical Services Ltd | Construction | 2018 |
| DWS Hydrotherapy Systems Ltd | Manufacturing | 2021 |
| DY Apparel Ltd | Wholesale & retail | 2025 |
| DY3PC Ltd | Other services | 2026 |
| Dycron Services Ltd | Construction | 2018 |
| Dylara Ltd | Wholesale & retail | 2022 |
| Dynamic Carpentry & Renovations Ltd | Construction | 2023 |
| Dynamic Hardware Ltd | Wholesale & retail | 2021 |
| Dynamic HW Group Limited | Wholesale & retail | 2019 |
| Dynamic Security Services UK Limited | Administrative & support | 2015 |
| Dynamic Water Solutions Limited | Professional & scientific | 2018 |
| Dynamics AX Consultants Limited | Information & communication | 2011 |
| Dynaminds Childcare Ltd | Health & social care | 2026 |
| Dynamix Impex Ltd | Wholesale & retail | 2024 |
| Dynasty Assests Limited | Real estate | 2022 |
| Dynasty Real Estate Limited | Real estate | 2017 |
| Dynki Limited | Information & communication | 2017 |
| Dzimbahwe Women Community Ltd | Health & social care | 2025 |
| E & a Rushton & Sons Limited | Extraterritorial | 2018 |
| E & G BAL Transport Ltd | Construction | 2023 |
| E & S Cleaners Limited | Administrative & support | 2019 |
| E & S Motors Holdings Limited | Financial services | 2018 |
| E Ball Limited | Construction | 2012 |
| E I C Imports Ltd | Wholesale & retail | 2015 |
| E N G Build Ltd | Manufacturing | 2018 |
| E Office (Midlands) Limited | Wholesale & retail | 2010 |
| E&L Investments (Midlands) Limited | Real estate | 2006 |
| E&P Group Limited | Wholesale & retail | 2021 |
| E&R Investments Limited | Health & social care | 2011 |
| E.B.M.L.M Estates Limited | Other services | 2024 |
| E.D.K Traction Limited | Other services | 2022 |
| E.D.U.S. Limited | Information & communication | 2000 |
| E.P.R Ventures Limited | Hospitality | 2018 |
| E.V.N.O.S. Enterprise Ltd | Wholesale & retail | 2026 |
| E101 HUB4 Ltd | Professional & scientific | 2023 |
| E11EVEN Property Holdings Limited | Construction | 2026 |
| E3 Systems Consulting Limited | Professional & scientific | 2014 |
| EA Harmony Ltd | Wholesale & retail | 2014 |
| EA Holdings Ltd | Professional & scientific | 2018 |
| EA People Ltd | Administrative & support | 2020 |
| EA Project Services Ltd | Professional & scientific | 2021 |
| EA Security Ltd | Other services | 2023 |
| Eadb Consultants Ltd | Information & communication | 2023 |
| Eagle Eyed Care Limited | Health & social care | 2018 |
| Eagle Investment Team Ltd | Real estate | 2024 |
| Eagles Care Limited | Health & social care | 2014 |
| EAL Pharma Ltd | Professional & scientific | 2025 |
| EAM Property Ltd | Real estate | 2023 |
| Early Years Leadership CIC | Education | 2021 |
| Earth Power Nutrition Ltd | Wholesale & retail | 2021 |
| East Legon Limited | Hospitality | 2022 |
| East Midlands Property Services Ltd | Real estate | 2015 |
| East Q Group Limited | Real estate | 2021 |
| East Trading Midlands Ltd | Other services | 2022 |
| Eastmeetswestglasgow Ltd | Administrative & support | 2017 |
| Easy Auto Midlands Limited | Wholesale & retail | 2024 |
| Easy Click Ltd | Wholesale & retail | 2025 |
| Easy Hire Walsall Ltd | Administrative & support | 2025 |
| Easy Home Rental Ltd | Real estate | 2021 |
| Easy Junk Rubbish Removal Ltd | Water & waste | 2023 |
| Easy Move Solutions Limited | Real estate | 2024 |
| Easy Rent Property Ltd | Real estate | 2019 |
| Easy Welding UK Ltd | Manufacturing | 2013 |