| Doctor Boiler Limited | Construction | 2025 |
| Doctor Kate Cosmetics Ltd | Health & social care | 2020 |
| Dogwarts Ltd | Arts & recreation | 2011 |
| Dolciedot Aesthetics Ltd | Other services | 2025 |
| Dollarboateng Group Limited | Wholesale & retail | 2021 |
| Domi Steel Ltd | Construction | 2020 |
| Dominion City Wolverhampton Ltd | Other services | 2025 |
| Dominion Cleaning Limited | Administrative & support | 2025 |
| Domino Global Trading Limited | Hospitality | 2019 |
| Domis Healthcare Ltd | Health & social care | 2023 |
| DON Investments Limited | Real estate | 2017 |
| DON Logistik Group Ltd | Transport & logistics | 2024 |
| Donnington Pharma Limited | Professional & scientific | 2020 |
| Doodlesquid Ltd | Information & communication | 2022 |
| Door Engineers Limited | Professional & scientific | 2025 |
| Door Plates Direct Limited | Wholesale & retail | 2020 |
| Door Solutions Direct Ltd | Wholesale & retail | 2014 |
| Doors & Windows Manufacturer Ltd | Manufacturing | 2017 |
| Dorielle Thompson Limited | Health & social care | 2015 |
| Dorimo Publishing Limited | Information & communication | 2018 |
| Dorocken Ltd | Administrative & support | 2024 |
| Doru Express Ltd | Transport & logistics | 2023 |
| Dotecrane Ltd | Wholesale & retail | 2024 |
| Dotty Magoo's Ltd | Hospitality | 2024 |
| Dotvelocity Limited | Professional & scientific | 2015 |
| Double Deuce GUN Shop Ltd | Wholesale & retail | 2024 |
| Double Deuce Ltd | Other services | 2015 |
| Double Dutch Wear Limited | Wholesale & retail | 2009 |
| Double M Holdings Limited | Administrative & support | 2001 |
| Doughs N Bros Ltd | Hospitality | 2022 |
| Douglas Hamilton Ltd | Wholesale & retail | 2009 |
| Dove Support Limited | Health & social care | 2025 |
| Dovecote Developments Limited | Construction | 2018 |
| Dovetail Cabinet Makers Limited | Construction | 2019 |
| Dowayne Transport Ltd | Transport & logistics | 2025 |
| Dowbudshad Ltd | Transport & logistics | 2024 |
| DOX Motorsport Ltd | Wholesale & retail | 2024 |
| Doyle & Goraya Ltd | Real estate | 2024 |
| DP Holdings and Investments Ltd | Real estate | 2025 |
| DP Jones & Co Limited | Professional & scientific | 2008 |
| DP World Global Freight TNZ Ltd | Transport & logistics | 2026 |
| DPA Contracts Ltd | Wholesale & retail | 2013 |
| DPB Plumbing and Heating Ltd | Construction | 2025 |
| DPG AI. Ltd | Financial services | 2023 |
| DPI Healthcare Ltd | Public administration | 2015 |
| DPI Solutions Limited | Manufacturing | 2004 |
| DPJ Process Servers Ltd | Other services | 2016 |
| DPM Stonemasonry and Building Services Ltd | Construction | 2021 |
| Dpwd Ltd | Transport & logistics | 2025 |
| Dpwdd Ltd | Transport & logistics | 2025 |
| DR Aarun Limited | Education | 2022 |
| DR Aneesh Ltd | Health & social care | 2022 |
| DR Implants Medical Tourism Ltd | Professional & scientific | 2018 |
| DR Kular Limited | Health & social care | 2021 |
| DR Maqsood Ltd | Health & social care | 2021 |
| DR N a PAL & Associates Limited | Health & social care | 2023 |
| DR Plastering&Rendering Ltd | Construction | 2013 |
| DR S&M Ahmad Holdings Limited | Real estate | 2025 |
| DR Sasha Ltd | Health & social care | 2025 |
| DR Skim Ltd | Construction | 2015 |
| DR V Tripathi Ltd. | Health & social care | 2015 |
| Dr.Gsc Associate Ltd | Health & social care | 2025 |
| DR3Y.07 Ltd | Transport & logistics | 2025 |
| Dradative Ltd | Wholesale & retail | 2024 |
| Dragon Employment Agency Ltd | Administrative & support | 2022 |
| Dragon Property Estates Ltd | Real estate | 2021 |
| Dragon Retail 525 Limited | Wholesale & retail | 2025 |
| Drake Finance Limited | Financial services | 2004 |
| Draketon Ltd | Wholesale & retail | 2025 |
| Draper Developments and Renovations Limited | Real estate | 2023 |
| Draper Installations Limited | Construction | 2013 |
| Dravity Ltd | Wholesale & retail | 2023 |
| Dream Construction Services Ltd | Construction | 2021 |
| Dream Craft Group Limited | Manufacturing | 2025 |
| Dream Express Furniture Ltd | Administrative & support | 2017 |
| Dream House Furnishings Ltd | Wholesale & retail | 2024 |
| Dream Time Properties Ltd | Real estate | 2025 |
| DREAMBODY4LIFE Ltd | Health & social care | 2023 |
| Dreamsai Milton Keynes Ltd | Other services | 2018 |
| Dreem Holmes Ltd | Real estate | 2025 |
| Dreoilin Limited | Professional & scientific | 2017 |
| Drillrite Limited | Construction | 2014 |
| Drinks Empire Ltd | Wholesale & retail | 2025 |
| Drinks Oasis Ltd | Wholesale & retail | 2018 |
| Driveforce Logistics Limited | Administrative & support | 2016 |
| Driveline Staffing Ltd | Administrative & support | 2026 |
| Driverservgeo Ltd | Transport & logistics | 2019 |
| Drke-Medical Plus Ltd | Health & social care | 2020 |
| Drop N Go Ltd | Transport & logistics | 2019 |
| DRS Heating Solutions Ltd | Construction | 2022 |
| Druids Heath Golf Club Limited | Other services | 1987 |
| DRYGON8 Limited | Administrative & support | 2017 |
| DS Advisory and Consultancy Ltd | Professional & scientific | 2026 |
| DS Commercial Construction Services Ltd | Professional & scientific | 2023 |
| DS Commercials Repairs Ltd | Wholesale & retail | 2024 |
| DS Fire and Electrical Ltd | Construction | 2018 |
| DS Training Services Ltd | Administrative & support | 2018 |
| DSD Property Investments Limited | Real estate | 2025 |
| Dsdk Limited | Wholesale & retail | 2013 |
| DSJ Consulting Group Ltd | Professional & scientific | 2020 |