| THE Slink Community CIC | Health & social care | 2024 |
| THE Sole Cleanse Ltd | Other services | 2025 |
| THE Vault, Creative Well-Being Centre Community Interest Company | Health & social care | 2013 |
| THE Wheatsheaf (Benton) Ltd | Hospitality | 2026 |
| THE Wonder Lounge Ltd | Wholesale & retail | 2024 |
| Thecreativebridge Limited | Professional & scientific | 2021 |
| Thegolfhub Ltd | Wholesale & retail | 2019 |
| Thehelpfulhandywoman Limited | Other services | 2025 |
| Thetechteam Limited | Information & communication | 2019 |
| Thompson Scaffolding Services Ltd | Construction | 2020 |
| Thompson's Deli Ltd | Hospitality | 2020 |
| Thornfield Enterprises Ltd | Wholesale & retail | 2026 |
| Thorns Nail & Beauty Limited | Professional & scientific | 2014 |
| Thought Consultancy Limited | Information & communication | 2001 |
| Thought Digital Limited | Extraterritorial | 2018 |
| Three Kings Brewery Limited | Manufacturing | 2012 |
| Three Motion Media Limited | Information & communication | 2010 |
| Tiapos Limited | Information & communication | 2016 |
| Tilery Equestrian Centre Limited | Agriculture & fishing | 2006 |
| Time Housing Consultancy Limited | Professional & scientific | 2022 |
| TMM BV Ltd | Manufacturing | 2018 |
| TOM Dowling Safety Solutions Limited | Manufacturing | 2016 |
| TOM Nolan Construction Limited | Construction | 2012 |
| TOO Good to LET Limited | Real estate | 2019 |
| Total Facilities Management NE Ltd | Administrative & support | 2025 |
| Total Properties NE Ltd | Real estate | 2019 |
| Tote Property Investments Limited | Real estate | 2020 |
| Toucan Digital Services Limited | Manufacturing | 2018 |
| Tough Construction (NE) Limited | Construction | 2005 |
| Touristnet UK Ltd | Hospitality | 2024 |
| TPM Telecom Ltd | Construction | 2014 |
| TPS Operations Limited | Real estate | 2013 |
| Trade Jack Limited | Information & communication | 2025 |
| Tranor Developments Limited | Real estate | 2007 |
| Tranquil Roots Ltd | Wholesale & retail | 2025 |
| Treehouse Tribe Ltd | Arts & recreation | 2026 |
| Trev Walker Ltd | Other services | 2016 |
| Triple Lima Entertainment Limited | Education | 2025 |
| Triptico Limited | Information & communication | 2012 |
| Triumph Health and Wellness CIC | Health & social care | 2024 |
| True Colours Decorating Ltd | Construction | 2024 |
| Truegrit Products Limited | Wholesale & retail | 2019 |
| TT2 (Holdings) Limited | Professional & scientific | 2007 |
| TT2 Limited | Transport & logistics | 2007 |
| TUB Food Co Ltd | Hospitality | 2024 |
| Tunajump Services Ltd | Real estate | 2024 |
| Two Four Property Developments Ltd | Real estate | 2023 |
| Tyne and Queer CIC | Arts & recreation | 2023 |
| Tyne Bridging Finance Limited | Financial services | 2023 |
| Tyne Chease Limited | Manufacturing | 2014 |
| Tyne Home Improvements Ltd | Construction | 2019 |
| Tyne Moulds & Machinery Company Limited | Manufacturing | 1976 |
| Tyne Moulds & Machinery Group Limited | Manufacturing | 2015 |
| Tyne N Wear Painters Ltd | Construction | 2016 |
| Tyne Newsagents Limited | Wholesale & retail | 2012 |
| Tyne Street Developments Ltd | Construction | 2022 |
| Tyne Tees Damp Proofing Limited | Construction | 2015 |
| Tyne Tunnel Conservatory Roofs Limited | Manufacturing | 2013 |
| Tyne Tunnel Glass Ltd | Manufacturing | 2012 |
| Tyne Tunnel Windows Ltd | Manufacturing | 2012 |
| Tyneclean Window Gutter Fascia Ltd | Administrative & support | 2021 |
| Tyneside Active Solutions Ltd | Education | 2024 |
| Tyneside Auto Centre Ltd | Professional & scientific | 2019 |
| Tyneside Bathrooms Ltd | Wholesale & retail | 2025 |
| Tyneside Care Services Ltd | Health & social care | 2026 |
| Tyneside Community Store C.I.C. | Wholesale & retail | 2023 |
| Tyneside Removals & Storage Ltd | Transport & logistics | 2021 |
| Tyneside Research Ltd | Wholesale & retail | 2026 |
| Tyneside Shipwrights Limited | Professional & scientific | 2021 |
| Tyneside Truck & Van World Ltd | Wholesale & retail | 2017 |
| Tyneview Homes Ltd | Real estate | 2022 |
| Tyneview Investments Limited | Hospitality | 2000 |
| Tyneview Scaffolding Limited | Construction | 2018 |
| UK Building & Insulation Ltd | Professional & scientific | 2023 |
| Ukdv Construction Limited | Information & communication | 2015 |
| Ukdv Holdings Limited | Information & communication | 2015 |
| Ukheatnpower Limited | Energy | 2019 |
| Ultimate Fitness North East Limited | Manufacturing | 2023 |
| ULTRA50 Club Ltd | Manufacturing | 2024 |
| Unicorn Sheet Metal Works Limited | Manufacturing | 2004 |
| Unique Fast FRY Limited | Hospitality | 2019 |
| Unisus Care Limited | Health & social care | 2020 |
| Unisus Group Limited | Professional & scientific | 2017 |
| Unisus Skills Limited | Education | 2022 |
| Unisus Wellbeing Limited | Health & social care | 2022 |
| Unite Technology Services Ltd | Information & communication | 2015 |
| United Recruitment System Ltd | Administrative & support | 2021 |
| United Sweets of America Limited | Wholesale & retail | 2012 |
| Universal Guard Limited | Financial services | 2025 |
| Uptons Vape Store Wallsend Ltd | Wholesale & retail | 2023 |
| Urvasi Hospitality Ltd | Hospitality | 2024 |
| VAO Software Development Ltd | Professional & scientific | 2024 |
| Vapers Lounge Whitley Bay Ltd | Wholesale & retail | 2019 |
| Varsity Global Ltd | Other services | 2017 |
| Velatrix Global Ltd | Information & communication | 2016 |
| Velvetmayne Ltd | Health & social care | 2017 |
| Venom Ventilation Ltd | Energy | 2022 |
| Ventpro Newcastle Limited | Construction | 2026 |
| Venue Live Ltd | Professional & scientific | 2023 |
| Venus Scaffolding Limited | Construction | 2015 |