| Stellium Networks Limited | Information & communication | 2016 |
| Stellium Properties Limited | Professional & scientific | 2018 |
| Stephen William Hair Design Limited | Other services | 2014 |
| Stepney Tyres Ltd | Wholesale & retail | 2021 |
| Stompin Ltd | Manufacturing | 2020 |
| Stsr Limited | Financial services | 2024 |
| Sublime Health & Aesthetics Ltd | Other services | 2022 |
| Subsole Ltd | Arts & recreation | 2014 |
| Suey House Limited | Hospitality | 2024 |
| Sunderland East END ABC CIC | Arts & recreation | 2019 |
| Sunholme Construction Limited | Professional & scientific | 2017 |
| SW Insulation Service Limited | Construction | 2018 |
| Swales Housing Group Limited | Real estate | 2019 |
| Swan Hunter (Lars) Limited | Professional & scientific | 2017 |
| Swan Hunter (NE) Limited | Professional & scientific | 2006 |
| SWL Scaffolding Ltd | Construction | 2018 |
| Sword Tiling Limited | Construction | 2026 |
| Sworow Leisure Ltd | Hospitality | 2012 |
| Sylhet Curry Ltd | Hospitality | 2018 |
| Syngas Dynamics Ltd | Professional & scientific | 2026 |
| SZR Properties Ltd | Real estate | 2025 |
| T Industrial Services Ltd | Construction | 2025 |
| T Y C (NE) Ltd | Hospitality | 2017 |
| T1 Barber Shop Limited | Other services | 2024 |
| Takk Enterprises Limited | Hospitality | 2012 |
| TALENT84 Ltd | Administrative & support | 2020 |
| Taliajay Ltd | Health & social care | 2025 |
| Tall Shots Talent Limited | Arts & recreation | 2025 |
| Tantalus Limited | Hospitality | 2001 |
| Tass Anti Slip Ltd | Manufacturing | 2018 |
| Taunton Close 1967 Limited | Extraterritorial | 2014 |
| Tausi Accounts Ltd | Professional & scientific | 2026 |
| Taxi CAB Services (Gateshead) Limited | Transport & logistics | 2019 |
| Taxi CAB Services (Hartlepool) Ltd | Transport & logistics | 2017 |
| Taylor & Stewart Properties Limited | Real estate | 2024 |
| Taylored Estates Limited | Construction | 2015 |
| Taylored Homes Limited | Real estate | 2010 |
| Taylored Investments NE Limited | Real estate | 2025 |
| Taylored Lettings (NE) Ltd | Real estate | 2008 |
| Taylored Living Limited | Real estate | 2022 |
| Taylored Professional Services Limited | Real estate | 2017 |
| Taylored Properties (NE) Ltd | Real estate | 2008 |
| Taylored Property Group Limited | Construction | 2008 |
| Taylored Property Holdings Limited | Real estate | 2015 |
| Taylored Property Investments Limited | Real estate | 2025 |
| Taylored Property NE1 Limited | Construction | 2017 |
| Taylored Property NE12 Alpha Limited | Administrative & support | 2014 |
| Taylored Residential Limited | Real estate | 2018 |
| TBS23 Limited | Manufacturing | 2026 |
| Tcne Group Ltd | Financial services | 2024 |
| Tea IMP Games Limited | Information & communication | 2021 |
| Techmarx (Electrical Contractors) Ltd | Construction | 2023 |
| Techmistry Ltd | Information & communication | 2023 |
| Technical Rope Access Solutions Limited | Other services | 2019 |
| Tecuna Limited | Information & communication | 2023 |
| Telospace UK Ltd | Real estate | 2025 |
| Tempest Gaming Limited | Arts & recreation | 2024 |
| Tempire Limited | Manufacturing | 2020 |
| Teo's Delicatessen Limited | Wholesale & retail | 2015 |
| Test and Lift Engineering Services Limited | Other services | 2021 |
| Testreach (UK) Limited | Information & communication | 2018 |
| Teteo Ltd | Transport & logistics | 2019 |
| Tetrics Limited | Construction | 2017 |
| Textile Zone Limited | Wholesale & retail | 2025 |
| TGM Houses Ltd | Real estate | 2024 |
| TH Joinery (North East) Limited | Construction | 2018 |
| Thandee-James Ltd | Wholesale & retail | 2021 |
| Thanga Co Ltd | Wholesale & retail | 2023 |
| THE BAD Cat Cafe and Rescue CIC | Arts & recreation | 2024 |
| THE Beauty Experience Ltd | Other services | 2025 |
| THE Biscuit Factory Foundation | Arts & recreation | 2011 |
| THE Biscuit Factory Limited | Arts & recreation | 2001 |
| THE Blue Spa Ltd | Other services | 2025 |
| THE Bongo Warriors Ltd | Arts & recreation | 2023 |
| THE Brandling Kitchen Ltd | Administrative & support | 2019 |
| THE Cannon (Earsdon) Ltd | Hospitality | 2026 |
| THE Collingwood Group NE Ltd | Wholesale & retail | 2025 |
| THE Convenience Spot Limited | Wholesale & retail | 2022 |
| THE Dog and Rabbit Brewery Ltd | Manufacturing | 2015 |
| THE DOT Bliss Limited | Wholesale & retail | 2024 |
| THE Dream Coat NE Ltd | Other services | 2025 |
| THE Eco Friendly Supplies Company Ltd | Wholesale & retail | 2024 |
| THE English Grammar Club Ltd | Education | 2019 |
| THE Family Tree Childrens' Day Nursery Limited | Health & social care | 2015 |
| THE French Collector UK Ltd | Wholesale & retail | 2025 |
| THE Geordieland Experience Ltd | Administrative & support | 2024 |
| THE Green Dimension Limited | Agriculture & fishing | 2023 |
| THE Indian Snack Lunch Box Express Ltd | Hospitality | 2024 |
| THE Jolly Bowman Battlehill Ltd | Hospitality | 2025 |
| THE Liquor Co. Ltd | Construction | 2015 |
| THE Look Marketing Ltd | Information & communication | 2026 |
| THE Manor House Hotel(Haltwhistle) Limited | Hospitality | 2021 |
| THE Mountain Boot Company Limited | Wholesale & retail | 1994 |
| THE Mylyceum Ltd | Education | 2021 |
| THE Nene Distillery Limited | Manufacturing | 2017 |
| THE North Tyneside Carers Centre | Other services | 1995 |
| THE Nutrition Exchange Ltd | Health & social care | 2025 |
| THE Railway NE Ltd | Hospitality | 2024 |
| THE Scent Touch Limited | Wholesale & retail | 2024 |
| THE Shelf Hairdressing Ltd | Other services | 2026 |