| Stelex Ltd | Wholesale & retail | 2024 |
| Stephen Westbury Limited | Professional & scientific | 2013 |
| Sterling Production Ltd | Hospitality | 2025 |
| Stick 'N' Step | Education | 2010 |
| Sticx Limited | Construction | 2011 |
| Stingo Properties Ltd | Real estate | 2024 |
| Stollies Cafe and Delicatessen Limited | Hospitality | 2016 |
| Stollies UK Limited | Hospitality | 2026 |
| Stoneway Court Management Company Limited | Households | 2002 |
| Stoneycroft Transform Ltd | Professional & scientific | 2025 |
| Stopford Digital Limited | Health & social care | 2025 |
| Stopford Healthcare Limited | Financial services | 2025 |
| Store 4 YOU Wallasey Ltd | Wholesale & retail | 2026 |
| Storytime With Santa Limited | Arts & recreation | 2016 |
| STP Courier Limited | Transport & logistics | 2025 |
| Straight Line Structural Repair Specialist Ltd. | Construction | 2003 |
| Strata Business Development Limited | Professional & scientific | 2001 |
| Stratton Tea Limited | Wholesale & retail | 2022 |
| Strebor Support Services Ltd | Professional & scientific | 2021 |
| Streetstrike.Io Ltd | Information & communication | 2026 |
| Structural and Civil Engineering Assistance Limited | Professional & scientific | 2020 |
| Structural Timber Group Ltd | Real estate | 2024 |
| Sublime Stores Holdings Limited | Financial services | 2025 |
| Sublime Stores Ltd | Hospitality | 2014 |
| Sugo Pizza Ltd | Hospitality | 2026 |
| SUH Systems Ltd | Extraterritorial | 2011 |
| Suited Leasing Limited | Administrative & support | 2023 |
| Summer Properties Limited | Real estate | 2004 |
| Sun SET Salons Ltd | Other services | 2024 |
| Sunrise Therapy Centre CIC | Health & social care | 2021 |
| Sunrise Therapy Ltd | Health & social care | 2021 |
| Sunsensation Limited | Other services | 2025 |
| Super Weird Substance Limited | Information & communication | 2014 |
| Supreme Aluminium Systems Ltd | Manufacturing | 2026 |
| Surebrick Limited | Real estate | 2000 |
| Suretax Ltd | Professional & scientific | 2024 |
| Surfacelux Limited | Construction | 2005 |
| Susan Jane Brassey Financial Services Ltd | Financial services | 2017 |
| Swanson Court Management Company Limited | Households | 2002 |
| Swat Removals Ltd | Transport & logistics | 2026 |
| Sweet Smiles (UK) Ltd | Health & social care | 2011 |
| Symbian Computer Services Limited | Information & communication | 2014 |
| Symbian Project Services Limited | Information & communication | 2010 |
| Systemize Solutions Limited | Information & communication | 2024 |
| Systems UK Ltd | Real estate | 2003 |
| Szabo Transport Ltd | Transport & logistics | 2011 |
| SZL Group Ltd | Education | 2018 |
| T and P Engineering Solutions Ltd | Manufacturing | 2025 |
| T J Turner Hair Ltd | Other services | 2024 |
| T&B Local Limited | Wholesale & retail | 2024 |
| T. Sullivan Engineering Limited | Manufacturing | 1991 |
| T.D.C (NW) Limited | Wholesale & retail | 2008 |
| T3D Architectural Ltd | Professional & scientific | 2023 |
| Tahir Logistics Ltd | Information & communication | 2023 |
| TAHIR001 Ltd | Wholesale & retail | 2020 |
| Tailored Floors Ltd | Wholesale & retail | 2011 |
| Talbot Murray Properties Ltd | Real estate | 2018 |
| TAM Ruislip Ltd | Hospitality | 2025 |
| Tamroster Ltd | Hospitality | 2025 |
| Tantrumedia Ltd | Information & communication | 2003 |
| Taskara Systems Limited | Information & communication | 2025 |
| Taurus Fencing (NW) Ltd | Construction | 2024 |
| Taxnerds Ltd | Professional & scientific | 2013 |
| Taya Projects Ltd | Construction | 2019 |
| Taylor Green Properties Ltd | Real estate | 2025 |
| Taylor MAY Consulting Ltd | Information & communication | 2018 |
| Taylor Phelan Ltd | Professional & scientific | 2008 |
| TB Plumbing & Heating Limited | Construction | 2025 |
| TBW Branding and Communications Limited | Administrative & support | 2008 |
| Tcad Properties Ltd | Administrative & support | 2025 |
| TDN Management Company Limited | Households | 2018 |
| Telegraph Inn Wallasey Limited | Hospitality | 2018 |
| Telvament Limited | Households | 1977 |
| Templum CIC | Administrative & support | 2024 |
| Tenant Angels Ltd | Professional & scientific | 2018 |
| Terrascape Industries Ltd | Manufacturing | 2025 |
| That's My Call Ltd | Administrative & support | 2015 |
| THE Acting Coach Limited | Arts & recreation | 2025 |
| THE Affordable Sofa Outlet Ltd | Other services | 2025 |
| THE Alocasia Company Ltd | Agriculture & fishing | 2025 |
| THE Bandman 11 Limited | Wholesale & retail | 2020 |
| THE Bearded G Ltd | Wholesale & retail | 2019 |
| THE Blessed BEE Ltd | Wholesale & retail | 2021 |
| THE Board YOU CAN Afford LLP | | 2013 |
| THE Bryer Patch Property Holdings Ltd | Real estate | 2026 |
| THE Butterfly Effect Wellness Community Interest Company | Health & social care | 2026 |
| THE Butty Station Ltd | Hospitality | 2026 |
| THE Capitol Limited | Hospitality | 2015 |
| THE Cat SIT Company Ltd | Other services | 2017 |
| THE Catering Agency Limited | Administrative & support | 2008 |
| THE Catering Agency Properties Ltd | Real estate | 2023 |
| THE Catholic Children's Society (Shrewsbury Diocese) Inc. | Health & social care | 1978 |
| THE Cavern Beatles Limited | Arts & recreation | 2011 |
| THE Clubhouse @ Masonic Hall Ltd | Hospitality | 2026 |
| THE Clubhouse @ Wirral GC Ltd | Hospitality | 2025 |
| THE Coffee Roast Cornerstone Events CIC | Education | 2026 |
| THE Comedy Core Limited | Arts & recreation | 2025 |
| THE Community I.T. Company Limited | Wholesale & retail | 2008 |
| THE Crossing Point | Health & social care | 2014 |
| THE Dental Hygiene Studio Ltd | Health & social care | 2019 |