| Premier Vein Treatments Limited | Health & social care | 2026 |
| Preservation Services Wirral Ltd | Professional & scientific | 2026 |
| Prestige Carpets Wallasey Ltd | Wholesale & retail | 2015 |
| Prime Properties Wirral Ltd | Real estate | 2025 |
| Prime Scalers Limited | Administrative & support | 2025 |
| Primfac Safety Limited | Professional & scientific | 2025 |
| Priority Care U.K. Limited | Information & communication | 2018 |
| Pristeen Windows Limited | Construction | 2007 |
| Prml Apparel Ltd | Manufacturing | 2025 |
| Pro-Tech Pavers Limited | Administrative & support | 2006 |
| Proactive Management (NW) Ltd | Households | 2026 |
| Proactive Property NW Ltd | Real estate | 2020 |
| Procalcs Limited | Financial services | 2010 |
| Process Connections Ltd | Wholesale & retail | 2026 |
| Proclimb Ltd | Construction | 2025 |
| Professional Carers (Wirral) Ltd | Health & social care | 2011 |
| Pronto Pizza (Wallasey) Ltd | Hospitality | 2021 |
| Propergeeks Limited | Other services | 2015 |
| Property Living Merseyside Ltd | Administrative & support | 2024 |
| Property Solutions Made Simple Limited | Real estate | 2019 |
| PROPERTY43 Limited | Real estate | 2025 |
| Proquant Solutions Limited | Professional & scientific | 2024 |
| Proquest Sports Massage & Personal Training Ltd | Other services | 2025 |
| PSH (Wirral) Ltd | Construction | 2018 |
| PSR Holdings Ltd | Administrative & support | 1997 |
| PTZ Properties Ltd | Real estate | 2024 |
| Public Urban Bars Ltd | Hospitality | 2015 |
| Purple Lime Merchandise Limited | Wholesale & retail | 2019 |
| Puzzlescc Ltd | Wholesale & retail | 2023 |
| PV Live Limited | Arts & recreation | 2019 |
| Pvbls Ltd | Administrative & support | 2022 |
| PW Property Solutions Ltd | Real estate | 2019 |
| Qknoxcapitol Ltd | Wholesale & retail | 2025 |
| Quadrotor Services Ltd | Agriculture & fishing | 2023 |
| Quality Flooring Solutions Ltd | Construction | 2026 |
| Quantum Health and Wellness Ltd | Wholesale & retail | 2008 |
| Quayside Port Services Limited | Manufacturing | 2015 |
| Queenswood Property Services Limited | Real estate | 2015 |
| Queer Clinic CIC | Education | 2024 |
| Quickserve Accounting and Training Ltd | Professional & scientific | 2018 |
| Quinlan Sinclair Property Services Limited | Real estate | 2017 |
| R & D Wirral Ltd | Wholesale & retail | 2021 |
| R & T Trading (NW) Ltd | Wholesale & retail | 2025 |
| R J Glazing Contractors Ltd | Construction | 2026 |
| R P Testing Services Ltd | Professional & scientific | 2023 |
| R&N Kurdish Barbers Limited | Other services | 2025 |
| R-Toy Limited | Manufacturing | 2025 |
| R.B. Autoworks Ltd | Administrative & support | 2007 |
| R.G Best Food & Wine Ltd | Wholesale & retail | 2026 |
| R.J Sayle Plumbing & Heating Services Ltd | Construction | 2022 |
| R.M.C. Relief Chef Ltd | Hospitality | 2013 |
| Rachel Green Interiors Limited | Wholesale & retail | 2024 |
| Radiate Serenity Ltd | Health & social care | 2026 |
| Rahewston- Consultants Limited | Professional & scientific | 2025 |
| Rainbowrise Estates Limited | Real estate | 2024 |
| Rake Lane Local Ltd | Wholesale & retail | 2025 |
| Rakoma Tech Ltd | Information & communication | 2024 |
| Rapid Heating Services Limited | Other services | 2014 |
| Raras Foods Ltd | Hospitality | 2026 |
| Rarebnb Ltd | Real estate | 2025 |
| RAS Systems Ltd | Construction | 2025 |
| Rashad Bankole Shop Ltd | Wholesale & retail | 2025 |
| Ravin Fit Limited | Arts & recreation | 2018 |
| RAW 4 Paws Ltd | Other services | 2015 |
| RB Mechanical Services Ltd | Construction | 2023 |
| Rdlg Building Supplies Ltd | Wholesale & retail | 2024 |
| Reality Rooms Limited | Arts & recreation | 2020 |
| Really Good Exposure Limited | Arts & recreation | 2026 |
| Reaygun TCG Ltd | Wholesale & retail | 2026 |
| Rebel Soul Enterprises C.I.C. | Information & communication | 2013 |
| Recipro (UK) Limited | Water & waste | 2010 |
| Recruit With US Ltd | Administrative & support | 2025 |
| Red Chilli Development Ltd | Real estate | 2025 |
| Red Robin Executive Communications Limited | Professional & scientific | 2021 |
| Redcap Hotels Ltd | Hospitality | 2026 |
| Redmere Group LLP | | 2016 |
| Redstone Park (2004) Limited | Households | 2005 |
| Refit Property Services Ltd | Construction | 2020 |
| Reflex Electrical Techniques Limited | Construction | 2010 |
| REG Heaven Ltd | Wholesale & retail | 2021 |
| Reid Fotheringham Consultancy Limited | Financial services | 2019 |
| Reliable Road Freight Ltd | Transport & logistics | 2024 |
| Remember When Wirral Tea Rooms Limited | Hospitality | 2019 |
| Reminisce Festival Life Limited | Arts & recreation | 2015 |
| Reminisce Festival Limited | Arts & recreation | 2015 |
| Rendering Techniques Ltd | Construction | 2017 |
| Rentals 28 Ltd | Real estate | 2024 |
| Resilient (NW) CIC | Education | 2021 |
| Resin Coating Specialists (RCS) Limited | Construction | 2013 |
| Resolve Roofing NW Ltd | Construction | 2026 |
| Resound Media Limited | Information & communication | 2010 |
| Retrospective Festival Ltd | Arts & recreation | 2025 |
| Revelation Records Ltd | Information & communication | 2021 |
| Reverse Northwest C.I.C. | Public administration | 2023 |
| Revive Aesthetics & Wellness Ltd | Other services | 2023 |
| Re_Dock Community Interest Company | Arts & recreation | 2008 |
| RF Creative Design Limited | Professional & scientific | 2016 |
| RFH Consultancy Services Ltd | Professional & scientific | 2014 |
| RFH Properties Ltd | Real estate | 2016 |
| RFT Developments Ltd | Construction | 2024 |