| Studio J Architects Limited | Professional & scientific | 2012 |
| Studio Noba UK Ltd | Professional & scientific | 2026 |
| Studio of Things Limited | Information & communication | 2013 |
| Studioaaa Ltd | Information & communication | 2025 |
| Studiomono Limited | Professional & scientific | 2016 |
| Stumps Club Shop Ltd | Wholesale & retail | 2025 |
| Stumps Sports Ltd | Manufacturing | 2024 |
| Sturdy Wings Childminding Ltd | Health & social care | 2025 |
| STW (Yorkshire) Ltd | Hospitality | 2025 |
| Style and Finch Limited | Manufacturing | 2021 |
| Style Engravers Limited | Manufacturing | 1988 |
| Styled by RHE Ltd | Other services | 2023 |
| Stylewall Acoustics Limited | Construction | 2018 |
| Stylove Girls Ltd | Wholesale & retail | 2023 |
| Styx Security Ltd | Administrative & support | 2022 |
| Subhan Mobiles Ltd | Wholesale & retail | 2025 |
| Subramanian & Co Limited | Health & social care | 2013 |
| Subtle Touches Limited | Hospitality | 2014 |
| Suda Solutions (UK) Ltd | Information & communication | 2018 |
| Sufi Pages Limited | Information & communication | 2024 |
| Sugden Heritage Ltd | Wholesale & retail | 2025 |
| Suit One Suit ALL Limited | Wholesale & retail | 2023 |
| Sulaymaniyah Arbil Limited | Other services | 2022 |
| Sulehri’S Private Ltd | Health & social care | 2023 |
| Sultan Westgate Ltd | Hospitality | 2026 |
| Suly Barber Limited | Other services | 2026 |
| Summat Market Ltd | Wholesale & retail | 2025 |
| Sun Minimarket Ltd | Wholesale & retail | 2019 |
| Sunbay Properties Ltd. | Real estate | 2026 |
| Sunbeam Engineering Design Ltd | Professional & scientific | 2024 |
| Sunburst 200 Limited | Other services | 2017 |
| Sunig Limited | Administrative & support | 2015 |
| Sunkissed Tanning Salon (Leeds) Ltd | Other services | 2026 |
| Sunniside Investments Limited | Real estate | 2015 |
| Sunnyhill Properties (Yorkshire) Limited | Real estate | 2017 |
| Sunnymede Limited | Health & social care | 2011 |
| Sunpark Wakefield Ltd | Hospitality | 2023 |
| Sunset GOA Limited | Hospitality | 2021 |
| Sunworks-Europe Limited | Administrative & support | 2007 |
| Super Drive Motors Limited | Wholesale & retail | 2022 |
| Super Health Direct Ltd | Health & social care | 2017 |
| Super Pound Wakefield Ltd | Wholesale & retail | 2024 |
| Super SEW Imports Limited | Wholesale & retail | 2015 |
| Super Snacks Ltd | Wholesale & retail | 2020 |
| Superchatpal Business Automation Ltd | Professional & scientific | 2020 |
| Superego Software Limited | Information & communication | 2017 |
| Supergood Bikers for Autism CIC | Health & social care | 2026 |
| Superior Mortgage Services Ltd | Financial services | 2020 |
| Superrecruit Limited | Administrative & support | 2024 |
| Supersys IT Services Limited | Information & communication | 2012 |
| Superyacht-Av Ltd | Professional & scientific | 2016 |
| Supotex Ltd | Information & communication | 2020 |
| Suppliance UK Ltd | Professional & scientific | 2023 |
| Supra Construction Ltd | Construction | 2017 |
| Supreme Adeh Multi Venture Ltd | Construction | 2025 |
| Supreme Taxis Private Hire Ltd | Transport & logistics | 2024 |
| Sure Revolution Limited | Administrative & support | 2017 |
| Surecare Plumbing Services Limited | Construction | 2014 |
| Surefit Logistics Limited | Real estate | 2021 |
| Surefix Tiling Solutions Limited | Construction | 2012 |
| Surepark Installations Limited | Manufacturing | 2008 |
| Surgicaloutlet Ltd | Wholesale & retail | 2023 |
| Surielle Limited | Professional & scientific | 2022 |
| Surveyx UK Ltd | Administrative & support | 2026 |
| Surya Estates Limited | Real estate | 2020 |
| Surya's Indian Lounge Limited | Hospitality | 2023 |
| Surya’S Indian Cuisine Ltd | Hospitality | 2024 |
| Sussex Hand Made Brick Limited | Manufacturing | 2006 |
| Sussu Ltd | Wholesale & retail | 2020 |
| Sustainable Plant Hire Solutions Ltd | Administrative & support | 2025 |
| Sustainable Trading Solutions Ltd | Construction | 2021 |
| Suxxess Dienstleistungs Agentur Limited | Professional & scientific | 2006 |
| SVJ Smile Real Estates Ltd | Real estate | 2026 |
| SVL Health Limited | Health & social care | 2019 |
| SW Europe Ltd | Construction | 2020 |
| Swagger Home Furnishings Ltd | Wholesale & retail | 2019 |
| Swags and Drapes Ltd | Wholesale & retail | 2020 |
| Swallow Hill Management Company Limited | Real estate | 2016 |
| Swallow Mill Leeds Development Limited | Real estate | 2020 |
| Swan Inheritance Investments Limited | Administrative & support | 2017 |
| Sweeper Keeper Ltd | Arts & recreation | 2023 |
| Sweet Telecom Limited | Information & communication | 2005 |
| Sweeting of Wakefield Limited | Wholesale & retail | 2009 |
| Swet Limited | Wholesale & retail | 2022 |
| Swift & Stones Property Solutions Ltd | Construction | 2023 |
| Swift Transit U.K. Limited | Transport & logistics | 2017 |
| Swiftdoctor Ltd | Health & social care | 2024 |
| Swillington Services Limited | Transport & logistics | 2025 |
| Swim Angels Ltd | Education | 2018 |
| Swinnow Park (Wetherby) Residents Management Company Limited | Households | 2025 |
| Switalskis LLP | | 2008 |
| Switch IT Support Limited | Information & communication | 2017 |
| Switch Water Supplier Limited | Professional & scientific | 2018 |
| Switched on YOU Ltd. | Professional & scientific | 2019 |
| SWS Joinery Limited | Construction | 2012 |
| SWT Web Ltd | Wholesale & retail | 2024 |
| Swyfft Home Delivery Ltd | Wholesale & retail | 2025 |
| Swyfft Logistics Limited | Wholesale & retail | 2025 |
| SXS Racing Ltd | Arts & recreation | 2014 |
| SY4SECURITY Limited | Information & communication | 2019 |