| SNF OIL and GAS Ltd | Manufacturing | 1985 |
| Snow Palaces Ltd | Real estate | 2025 |
| Snowden Property Ltd | Real estate | 2024 |
| SO FM Ltd | Extraterritorial | 2014 |
| Sobear Limited | Wholesale & retail | 2025 |
| Soccer 90 Limited | Information & communication | 2016 |
| Soccer Supplier Ltd | Wholesale & retail | 2021 |
| Social Housing & Debt Consultancy Services Limited | Professional & scientific | 2018 |
| Social Spaces Solutions Ltd | Real estate | 2026 |
| Society of Local Authority Chief Executives and Senior Managers | Other services | 1992 |
| Socket Guardian Limited | Public administration | 2025 |
| Soda Group Limited | Construction | 2008 |
| Sofa Smart Ltd | Wholesale & retail | 2021 |
| Sofkids Ltd | Wholesale & retail | 2026 |
| Sofraexpresswkfld Ltd | Hospitality | 2025 |
| Soft Touch Beds Limited | Manufacturing | 2018 |
| SOH Piercing & Lasering Limited | Arts & recreation | 2024 |
| Solace in Business Ltd | Professional & scientific | 1996 |
| Solar Maintenance Ltd | Construction | 2026 |
| Solar Tron Ltd | Professional & scientific | 2025 |
| Solarcare Ltd | Manufacturing | 2023 |
| Solarium EA Ltd | Other services | 2025 |
| Solaworx Ltd | Construction | 2025 |
| Solid Academy Ltd | Information & communication | 2020 |
| Solros Consulting Limited | Construction | 2017 |
| Solus Advisors Limited | Professional & scientific | 2013 |
| Solus Developments Limited | Construction | 2019 |
| Solutions (Yorkshire) Limited | Health & social care | 1999 |
| Solutions Lords Ltd | Other services | 2016 |
| Solved Inc Ltd | Construction | 2025 |
| Solway Foods Holdings Limited | Professional & scientific | 1994 |
| Solway Foods Limited | Manufacturing | 1987 |
| Some Associates Limited | Administrative & support | 2022 |
| Some Properties Limited | Real estate | 2009 |
| Somerby Woods Limited | Professional & scientific | 2017 |
| Somnia Beds Ltd | Wholesale & retail | 2025 |
| Sonador Furniture Ltd | Manufacturing | 2020 |
| Sonel Galtiu Ltd | Manufacturing | 2022 |
| Sonnen Marketing Limited | Professional & scientific | 2024 |
| Sood Property Portfolio Ltd | Real estate | 2022 |
| Sopheli Ltd. | Professional & scientific | 2018 |
| Sorella Catering & Events Ltd | Hospitality | 2025 |
| Sorin J Ltd | Real estate | 2026 |
| Soul Motion Limited | Wholesale & retail | 1994 |
| Sound Mind Wellness UK Limited | Wholesale & retail | 2025 |
| Sound of Angels Music Limited | Arts & recreation | 2025 |
| Sound Solution Services Yorkshire Limited | Arts & recreation | 2014 |
| Sourceybros Limited | Real estate | 2024 |
| South East Asia Advanced Engineering Services Limited | Professional & scientific | 2008 |
| South of Heaven Tattoo Studio Limited | Arts & recreation | 2019 |
| South Pacific Joinery Limited | Construction | 2026 |
| South Yorkshire Locum Services Limited | Health & social care | 2012 |
| Sovan Ltd | Transport & logistics | 2023 |
| Sovereign Agricultural Services Limited | Manufacturing | 1995 |
| Sovereign Park Enterprises Limited | Financial services | 2008 |
| SP ( UK ) Distributions Ltd | Wholesale & retail | 2018 |
| SP Decoration Ltd | Construction | 2019 |
| SP Joinery Solutions Ltd | Construction | 2025 |
| SP Training Solutions Limited | Professional & scientific | 2006 |
| SP UK Properties Limited | Real estate | 2022 |
| Sp&A Enterprises Ltd | Professional & scientific | 2024 |
| Spa Building Services Ltd. | Construction | 2001 |
| Spa Electrical (Wakefield) Limited | Construction | 2016 |
| Spa Holdings (Wakefield) Ltd. | Real estate | 2001 |
| Space Aesthetics Limited | Other services | 2026 |
| Space DP Holdings Limited | Financial services | 2023 |
| Space House 5 Ltd | Transport & logistics | 2020 |
| Space Interior Building Services Limited | Construction | 2015 |
| Space Solutions Management Ltd | Real estate | 2024 |
| Space Student & Professional Lets Ltd | Real estate | 2014 |
| Spacekick Company | Financial services | 2016 |
| Spacium Architecture Ltd | Professional & scientific | 2020 |
| Spacium Ltd | Professional & scientific | 2023 |
| Spaf UK Limited | Wholesale & retail | 2023 |
| Spakle Ltd | Manufacturing | 2023 |
| SPARES4APPLIANCES Ltd | Wholesale & retail | 2023 |
| Spark Solutions N.E Ltd | Construction | 2022 |
| Sparkling Sapphire Ltd | Administrative & support | 2024 |
| Sparks Auto Electrical Limited | Wholesale & retail | 2003 |
| SPARKY892 Express Limited | Transport & logistics | 2019 |
| Spartan Defence Ltd | Public administration | 2024 |
| Sparton Real Estate Limited | Real estate | 2019 |
| Spcm Limited | Wholesale & retail | 2012 |
| Special Transactions and Negoce (S.T.A.N.) Ltd. | Manufacturing | 2007 |
| Specialised Waste Solutions Ltd | Water & waste | 2006 |
| Specialist Ceiling Services Holdings Limited | Professional & scientific | 2002 |
| Specialist Contracting & Consultancy Limited | Professional & scientific | 2018 |
| Specialist Healthcare Ltd | Health & social care | 2025 |
| Spectrum Build Solutions Ltd | Wholesale & retail | 2026 |
| Spectrum Community Health C.I.C. | Health & social care | 2010 |
| Spectrum Decorating Solutions Ltd | Construction | 2021 |
| Spectrum Labour Solutions Ltd | Construction | 2019 |
| Spectrum Learn and Develop Ltd | Education | 2018 |
| Spectrum People | Health & social care | 2013 |
| Speedy Auto Buyer Limited | Wholesale & retail | 2024 |
| Speianu Ltd | Construction | 2022 |
| Spencer Civil Engineering Ltd | Construction | 2018 |
| Spencer Construction Ltd | Extraterritorial | 2021 |
| Spencer Holdings (Leeds) Ltd | Financial services | 2019 |
| Spencer Plant Hire Ltd | Administrative & support | 2019 |