| 1WEIGH Limited | Administrative & support | 2005 |
| A M Long Limited | Transport & logistics | 2003 |
| A.B.C. Easy-Learn Limited | | 1986 |
| A.F.M. Europe Limited | Wholesale & retail | 1978 |
| ABC Optical Limited | Wholesale & retail | 2017 |
| Accenan Limited | Information & communication | 2005 |
| Acentra Trading Limited | Administrative & support | 2026 |
| Achievable Group Ltd | Administrative & support | 2023 |
| Acorn Creatives NE Ltd | Other services | 2021 |
| ACT UK Group (Fife) Limited | Manufacturing | 2022 |
| Advanced Electric Machines Group Ltd | Financial services | 2019 |
| AGC Enterprises Ltd | Wholesale & retail | 2024 |
| AJF Properties NE Ltd | Real estate | 2019 |
| Alan Birkett Ltd | Information & communication | 2007 |
| Albany Office Equipment (Wholesale) Limited | Wholesale & retail | 1964 |
| Alikia Ltd | Real estate | 2022 |
| Allison Heating Limited | Construction | 2002 |
| Alpro Bidco 1 Ltd | Other services | 2025 |
| Amies Civil Engineering Limited | | 1978 |
| Andtech Systems Limited | Administrative & support | 2026 |
| Apex Litigation Group Ltd | Administrative & support | 2022 |
| Appo Limited | Other services | 2010 |
| Arbeia Limited | Professional & scientific | 2002 |
| Arts 4 Wellbeing | Health & social care | 1995 |
| Ashwood Property Developments Limited | Construction | 1990 |
| AST Investments Partnership Limited Liability Partnership | | 2026 |
| Astrofade Limited | Construction | 1983 |
| Atlantic Belgravia Limited | Administrative & support | 2007 |
| Atroni Services Limited | Wholesale & retail | 2023 |
| Aurora Properties (Rental) Limited | Real estate | 2017 |
| Aurora Properties (Sale) Limited | Real estate | 2017 |
| Avenue Pharmacy (Sunderland) Limited | Wholesale & retail | 2002 |
| Awas Shop Ltd | Wholesale & retail | 2026 |
| B Hill Building and Property Maintenance Limited | Construction | 2006 |
| Balmbra's Limited | Hospitality | 2004 |
| Barbour (Footwear) Limited | Wholesale & retail | 1982 |
| Barbour (Liddesdale) Ltd | Manufacturing | 1978 |
| Barkwell Limited Partnership | | 2005 |
| Bathrooms Today Ltd | Construction | 2018 |
| Bengal Spice Howden Ltd | Hospitality | 2022 |
| Benwell Convenience Store Ltd | Wholesale & retail | 2025 |
| BG Estates NE Ltd | Real estate | 2019 |
| Bill Upsall (Sports) Limited | Manufacturing | 1979 |
| Blacks Corner Culture House Ltd | Hospitality | 2026 |
| Blue Door UK Property Limited | Real estate | 2026 |
| Blue Dragon Assets Ltd | Administrative & support | 2024 |
| Boldon Golf Club Limited(The) | Arts & recreation | 1925 |
| Boldon Property Development Limited | Real estate | 2006 |
| Breakaway Snooker and Pool Services Limited | Wholesale & retail | 2003 |
| Brian Debnam and Associates Ltd | Arts & recreation | 2003 |
| Bullseye Competitions Ltd | Other services | 2025 |
| Bunrad Limited | Health & social care | 2013 |
| C S Deliveries Limited | Transport & logistics | 2007 |
| Camden Estates (North Shields) Limited | Real estate | 1939 |
| Canford Manufacturing Limited | Real estate | 1996 |
| Cantina Brasil UK Ltd | Wholesale & retail | 2024 |
| Carlton House Maintenance Limited | Households | 1988 |
| Cartmel Park Management Limited | Hospitality | 1998 |
| Casa Montalbano Ltd | Hospitality | 2019 |
| Castle Building Services (South) Limited | Construction | 2016 |
| Catc Compliance Ltd | Construction | 2020 |
| Central Heating Spec Limited | Construction | 2006 |
| Certaindon Limited | Professional & scientific | 1987 |
| Chandeliers by Annette Limited | Hospitality | 2020 |
| Chill 2023 Ltd | Financial services | 2023 |
| Ckkg Limited | Hospitality | 2025 |
| Classic Masonry Limited | Construction | 1991 |
| Classic Tiles of South Shields Limited | Wholesale & retail | 2005 |
| Cleadon Estates Limited | Professional & scientific | 1952 |
| Coating Repair Specialists Limited | Construction | 2006 |
| Coffee Distributors Limited | Manufacturing | 1961 |
| Coldconnection Limited | Wholesale & retail | 1999 |
| Colmans Caterers Limited | Hospitality | 2003 |
| Commco Print Solutions Limited | Other services | 2001 |
| Commercial Edge Consulting Limited | Professional & scientific | 2007 |
| Complete Heat Solutions Limited | Construction | 2006 |
| Conifer Court (Newcastle) Management Company Limited | Households | 1996 |
| Consultants in Contact Limited | Professional & scientific | 2005 |
| Conway Christie Newcastle Ltd | Real estate | 2024 |
| Cooke & Co Estate Agents Limited | Real estate | 2007 |
| Coombe Holdings NE Ltd | Professional & scientific | 2024 |
| Cooperlets Limited | Real estate | 2007 |
| Core Trident Group Ltd | Administrative & support | 2023 |
| Crest House Property Limited | Real estate | 1998 |
| Critical Tortoise Limited | Professional & scientific | 2001 |
| Cross Scaffolding Limited | Wholesale & retail | 2007 |
| Crozier Fisheries Limited | Wholesale & retail | 2003 |
| Curry Garden (Gateshead) Limited | Hospitality | 2007 |
| Custodian Total Security Services Limited | Other services | 1976 |
| CVN Print Limited | Manufacturing | 2002 |
| D & L Roofing (N.E.) Limited | Construction | 2007 |
| D & P Trophies Limited | Manufacturing | 2003 |
| D & W LEE & Family Limited | Wholesale & retail | 2003 |
| Dalou Limited | Hospitality | 1985 |
| Dalziel Ingredients Limited | Manufacturing | 1976 |
| Danciu Ltd | Transport & logistics | 2019 |
| Data Book-Keeping Services Limited | Professional & scientific | 1995 |
| Dave Kendall Limited | Construction | 2007 |
| David High Interiors Ltd | Construction | 2002 |
| Davy Bank Test Centre Limited | Wholesale & retail | 2007 |