| Debére Holdings Limited | Financial services | 2022 |
| Derek's School of Motoring Limited | Education | 2003 |
| Derwent Valley Estates Limited | | 1974 |
| Devign Ltd | Information & communication | 2007 |
| DF Leisure Ltd | Hospitality | 2020 |
| Diane Mactavish Consultancy Ltd | Professional & scientific | 2023 |
| Dobsons Estate Agents Limited | Real estate | 2003 |
| Dragonfly Venture (UK) Limited | Manufacturing | 2004 |
| DSM Fabrications Limited | Manufacturing | 2005 |
| DT 11 Ltd | Hospitality | 2008 |
| Duncan Bennett Public Relations Ltd | Professional & scientific | 2024 |
| Durham Sheet Metal Works Limited | Manufacturing | 1955 |
| E Wakenshaw (Builders) Limited | Construction | 1987 |
| E. Turnbull & SON Limited | Other services | 1924 |
| Eastern Developments Limited | | 1984 |
| Eastkeen Ltd | Extraterritorial | 2003 |
| Eddleston Ltd | Extraterritorial | 2003 |
| Element Media Limited | Professional & scientific | 2014 |
| Elliot Stonehouse Ltd | Real estate | 2023 |
| Empire Property Investment Global Limited | Real estate | 2019 |
| Enviro - Clear Limited | Other services | 1999 |
| Ergo Flex Enterprises Limited | Professional & scientific | 2008 |
| Euro Industrial Services Ltd | Administrative & support | 2016 |
| Everlasting Care Ltd | Health & social care | 2004 |
| F.E. Maughan (Estates) Limited | Real estate | 1936 |
| Fabled Games Ltd | Information & communication | 2022 |
| Fareed Traders Ltd | Wholesale & retail | 2026 |
| Farmau Limited | | 1987 |
| FCB Associates Limited | Professional & scientific | 2022 |
| Featonby's Properties Limited | Real estate | 2019 |
| Fenham Taxis Ltd | Transport & logistics | 2006 |
| Fineandsandy Ltd | Wholesale & retail | 2018 |
| First Class Supply & Tutoring Limited | Administrative & support | 2004 |
| First Universal Ltd | Mining & quarrying | 2003 |
| Fitzpatrick Glaziers Limited | Construction | 1978 |
| Fix-A-Chip (Tyneside) Limited | Wholesale & retail | 2007 |
| Floralife Europe Limited | Manufacturing | 2025 |
| Foremost Tyres (Sunderland) Limited | Transport & logistics | 2007 |
| Francesca Estates Ltd | Real estate | 2026 |
| G-Force (NE) Ltd | Manufacturing | 2015 |
| G. Whitfield Limited | Wholesale & retail | 1957 |
| G.M.K. Printers Limited | | 1973 |
| GAP Ice Ltd | Water & waste | 2017 |
| Gary Craig Architectural Services Limited | Professional & scientific | 2004 |
| Gary Wilson Snooker Limited | Arts & recreation | 2019 |
| GC Drywall Ltd | Construction | 2024 |
| Geordie-Gin Distribution Ltd | Manufacturing | 2004 |
| George Vardy Limited | Construction | 1980 |
| Gibson Bearfoot Limited | Professional & scientific | 2008 |
| Gibson-Lillie Limited | Financial services | 2007 |
| Ginger Indian Street Food Ltd | Hospitality | 2020 |
| GK Timber Ltd | Wholesale & retail | 2026 |
| Glyn Carter Building Services Limited | Construction | 2007 |
| Gowland and Dawson Holdings Limited | Financial services | 2018 |
| Graham Dickinson Agencies Limited | Manufacturing | 2008 |
| Graham's Barber Shop Limited | Other services | 2003 |
| Grainco Scotland Limited | Extraterritorial | 2002 |
| Gritgalt Limited | | 1971 |
| Gsmb Holdings Ltd | Financial services | 2025 |
| H R Supplies Limited | Real estate | 1995 |
| H. Nichol & SON (Gateshead) Limited | Real estate | 1964 |
| Hairtalk Limited | Other services | 2007 |
| Halley Johnston Associates Limited | Administrative & support | 2007 |
| Harvard Consultant Services Limited | Information & communication | 1986 |
| Harvestmall Enterprise Ltd | Wholesale & retail | 2019 |
| Hawkfest Limited | Arts & recreation | 2006 |
| Hedley Bowling Limited | Wholesale & retail | 2006 |
| Hench Education Ltd | Professional & scientific | 2022 |
| HLA Group Holdings Limited | Financial services | 2024 |
| Hobson Golf Club Limited | Arts & recreation | 2002 |
| Home OR Away Holiday Shop Limited | Administrative & support | 2003 |
| Horizon Sports & Wellbeing Academy CIC | Education | 2026 |
| HOSPITALITY2025 Limited | Hospitality | 2025 |
| I & J Electrics Limited | Construction | 2006 |
| Impack Branding Ltd | Professional & scientific | 2023 |
| Impact Print & Design (N.E.) Ltd. | Manufacturing | 2002 |
| Infection Music Limited | Manufacturing | 2003 |
| Inline Media Ltd | Information & communication | 2019 |
| J & N PVT Ltd | Wholesale & retail | 2020 |
| J G Sawyers & Sons Limited | Real estate | 2007 |
| J Shipley & Co Heating Limited | Construction | 2005 |
| J'Bena Ltd | Hospitality | 2022 |
| J.A.S. Services (NE) Ltd | Real estate | 2003 |
| J.W.Alder & Sons(Sunderland)Limited | Wholesale & retail | 1951 |
| Jacks Hendon Limited | Hospitality | 2019 |
| Jackson Hogg Future Leaders Limited | Extraterritorial | 2022 |
| James Burrell Limited | Wholesale & retail | 1926 |
| John Hudson Music Productions Limited | Arts & recreation | 2000 |
| John T Entertainment Ltd | Information & communication | 2025 |
| John Wheeler Solutions Limited | Other services | 2006 |
| Jopling & Turnbull Limited | Transport & logistics | 1976 |
| Josh & TOM Ltd | Professional & scientific | 2002 |
| Kindback Limited | | 1985 |
| Kingfisher Media Limited | Information & communication | 2006 |
| Kllp Events Ltd | Administrative & support | 2026 |
| KP Simpson Accountants LLP | | 2025 |
| Kryos Limited | Wholesale & retail | 2026 |
| KSL7 Limited | Financial services | 2020 |
| LAA Invest Ltd | Real estate | 2023 |
| Labour UK Ltd | Administrative & support | 2020 |