| Sagegreen HR Limited | Professional & scientific | 2013 |
| Saha Vegan Limited | Manufacturing | 2019 |
| Sail & PEG LLP | | 2018 |
| Saini Traders UK Limited | Wholesale & retail | 2024 |
| Saint Andrews Management Ltd | Real estate | 2015 |
| Saint Johns Yard Ltd | Hospitality | 2022 |
| Saint-Vincent Pharma Ltd | Wholesale & retail | 2025 |
| SAJ Horizon Limited | Information & communication | 2016 |
| Salamanca Limited | Professional & scientific | 2009 |
| Salamis Holdings Ltd | Financial services | 2016 |
| Salar Solutions Limited | Agriculture & fishing | 2005 |
| Salgo Solution Ltd | Manufacturing | 2022 |
| Sally Henderson Limited | Professional & scientific | 2016 |
| Sallyathome Limited | Professional & scientific | 2006 |
| Salon Employers Association Limited | Other services | 2025 |
| Salt Brand Consultancy Limited | Professional & scientific | 2023 |
| Salus Vita Ltd | Health & social care | 2023 |
| Salvadori Court Management Limited | Professional & scientific | 2002 |
| SAM Harvey Associates Ltd | Professional & scientific | 2026 |
| SAM John Creates Ltd | Information & communication | 2026 |
| SAM R Lewis Limited | Professional & scientific | 2011 |
| Samara Power Holdings Ltd | Financial services | 2025 |
| Samba Labs Ltd | Information & communication | 2021 |
| Sami J CUT Ltd | Other services | 2025 |
| Samj Ltd | Real estate | 2019 |
| Sammi Taylor Media Limited | Other services | 2026 |
| Samphire and Associates Limited | Administrative & support | 2010 |
| Sampling & Blending Solutions Ltd | Manufacturing | 2025 |
| Sampling-Blending Consultants Ltd | Professional & scientific | 2025 |
| Sana Global Ltd | Wholesale & retail | 2024 |
| Sancus Services Limited | Administrative & support | 2011 |
| Sandellas Ltd | Wholesale & retail | 2019 |
| Sandgate Road Practice Ltd | Health & social care | 2023 |
| Sandhurst Road (Tunbridge Wells) Management Company Limited | Households | 2004 |
| Sandner (UK) Limited | Wholesale & retail | 2009 |
| Sandpiper Accountancy Limited | Professional & scientific | 2014 |
| Sandrock House (Tunbridge Wells) Residents Company Limited | Households | 1989 |
| Sandstone Quarry Apartments Freehold Company Limited | Households | 2019 |
| Sangha Brands Ltd | Information & communication | 2018 |
| Sankeys Fishmongers Limited | Wholesale & retail | 2009 |
| Sankeys Speldhurst Limited | Hospitality | 2025 |
| Sanoko Enterprises Ltd | Real estate | 2025 |
| Sarah Ambrose Business Consultants Limited | Other services | 2014 |
| Sarah Burrows Interiors Limited | Professional & scientific | 2025 |
| Sarah Staar Business School Ltd | Other services | 2012 |
| Sarah Wells Consulting Ltd | Information & communication | 2022 |
| Sarah Whyte (UK) Limited | Professional & scientific | 2013 |
| Sarah Whyte LLP | | 2013 |
| Sarahs Little Stars Ltd | Health & social care | 2022 |
| Saregen Limited | Professional & scientific | 2020 |
| Sarissa Ltd | Wholesale & retail | 2010 |
| Sartix Limited | Information & communication | 2024 |
| Sarton FM Limited | Information & communication | 2014 |
| Savage Corporation Ltd | Transport & logistics | 2020 |
| Savage Property Ltd | Real estate | 2025 |
| Save on Safes Ltd | Extraterritorial | 2009 |
| Saved Studios Limited | Wholesale & retail | 2025 |
| Sawyers Parks (UK) Limited | Extraterritorial | 2006 |
| Sawyers Parks Limited | Hospitality | 2002 |
| SAX by C. Sharp Ltd | Arts & recreation | 2021 |
| Saxon Hall Limited | Administrative & support | 2003 |
| SAY SO Media Limited | Information & communication | 2008 |
| Sayani Medical Limited | Health & social care | 2010 |
| Sazzam Ltd | Wholesale & retail | 2024 |
| Scaffolding Equipment Supplies Ltd | Wholesale & retail | 2014 |
| Scallywags Dog Care Ltd | Other services | 2026 |
| Scalplab Ltd | Other services | 2026 |
| Scarlett Consultants Limited | Professional & scientific | 2025 |
| SCC Food and Drinks LLP | | 2020 |
| SCG Consult Ltd | Information & communication | 2023 |
| Schoeman Violin Solutions Ltd | Arts & recreation | 2016 |
| School Daze Ltd | Information & communication | 2026 |
| School of Security Studies Limited | Education | 2023 |
| Scienta Group Limited | Financial services | 2022 |
| Scienta Search Limited | Administrative & support | 2017 |
| Scientific Update Limited | Professional & scientific | 2014 |
| Scme Holdings Limited | Construction | 2025 |
| Scocius Ltd | Wholesale & retail | 2025 |
| Scoh Ltd | Health & social care | 2012 |
| Scooped Limited | Information & communication | 2024 |
| Scorpion Consulting Limited | Information & communication | 2026 |
| Scott Riley Ltd | Information & communication | 2014 |
| Scrattmore Properties Ltd | Real estate | 2024 |
| Scrawsy Limited | Information & communication | 2024 |
| Screenography Limited | Information & communication | 2023 |
| Screenwave Ltd | Information & communication | 2025 |
| Scuffs and Scratches Limited | Manufacturing | 2005 |
| Sd&A Limited | Professional & scientific | 2016 |
| Sdlc Limited | Professional & scientific | 2017 |
| Sdmmhold UK Ltd | Manufacturing | 2020 |
| SDS Drylining Holdings Limited | Professional & scientific | 2018 |
| SDS Drylining Limited | Construction | 2015 |
| SE Energy Holdings Limited | Financial services | 2025 |
| SE Energy Solutions Limited | Construction | 2020 |
| Sea the Difference Ltd | Other services | 2014 |
| Seabrook Architectural Studio Limited | Professional & scientific | 2023 |
| Seagull Equestrian Events Management Limited | Arts & recreation | 2015 |
| Sean & Siana Properties Ltd | Real estate | 2020 |
| Sean Finch Creative Service Management Ltd | Professional & scientific | 2019 |
| Search Press Limited | Information & communication | 1968 |