| EAT Think Create Limited | Extraterritorial | 2022 |
| Ebsa Horizons CIC | Education | 2025 |
| Eco Renewables SW Ltd | Construction | 2023 |
| Eco-Friendly Publishing Limited | Extraterritorial | 2017 |
| Edwina Vincent Limited | Information & communication | 2014 |
| EG Autos Ltd | Wholesale & retail | 2023 |
| Elan TLC Ltd | Professional & scientific | 2006 |
| Electric Candlelight Ltd | Information & communication | 2023 |
| Elobe Ltd | Administrative & support | 2002 |
| Eloma Limited | Hospitality | 2023 |
| Emma Vowles Limited | Wholesale & retail | 2010 |
| Emma's Stoke Gabriel Ltd | Hospitality | 2025 |
| Emood Limited | Wholesale & retail | 2025 |
| Employee Owners Group Limited | Construction | 2006 |
| Energy Plant R&D Limited | Construction | 2013 |
| Engage in Science Limited | Education | 2013 |
| English in Totnes Limited | Education | 2010 |
| Equitone Limited | Wholesale & retail | 2022 |
| ESP Properties Ltd | Real estate | 2023 |
| Ethical Sustainable Properties C.I.C. | Households | 2026 |
| Ethos Distribution Limited | Wholesale & retail | 2020 |
| Eunoia Content Ltd | Information & communication | 2019 |
| European Therapeutic Education Group Ltd. | Education | 2013 |
| Eveleighs (Devon) Limited | Real estate | 1950 |
| Evie Retro Ltd | Energy | 2024 |
| Evolve Build Maintain Limited | Construction | 2013 |
| Eyes Down Ltd | Professional & scientific | 2011 |
| F & E Holdings Limited | Financial services | 2018 |
| F I Recruitment Ltd | Administrative & support | 2021 |
| Fabled Ltd | Professional & scientific | 2024 |
| Face (Devon) Limited | Construction | 2014 |
| Factory Cooperage Management Limited | Households | 2023 |
| Fairfield Twelve LLP | | 2014 |
| Fairflow Systems Design Ltd | Information & communication | 2012 |
| Faithfull Movie Company Limited | Information & communication | 2019 |
| Fallapit House Management Company Limited | Administrative & support | 2008 |
| Falls Response Devon Ltd | Health & social care | 2026 |
| Family Sutton Solutions Limited | Construction | 2019 |
| Fandemiq Ltd | Information & communication | 2026 |
| FAR Reach Digital Ltd | Information & communication | 2026 |
| Faraday Veterinary Neuroimaging Ltd | Professional & scientific | 2025 |
| Fayre Trade Fairy (Totnes) Ltd | Wholesale & retail | 2025 |
| FE Invest Ltd | Real estate | 2024 |
| FE Residentials Ltd | Real estate | 2026 |
| Fear Hills Limited | Administrative & support | 2023 |
| Ferrari LA Scuderia Films Limited | Information & communication | 2011 |
| Ferrite Ltd | Wholesale & retail | 2020 |
| Ferry Boat International Limited | Administrative & support | 2010 |
| Field Recordings From the Future CIC | Arts & recreation | 2025 |
| Fire and Dust Ltd | Arts & recreation | 2011 |
| Firefly Totnes Ltd | Wholesale & retail | 2023 |
| First Agency Direct Limited | Health & social care | 2016 |
| Firthphotonics Ltd | Professional & scientific | 2026 |
| Fishtek Marine Limited | Agriculture & fishing | 2016 |
| Fliss James Ltd | Health & social care | 2024 |
| Flooer Limited | Wholesale & retail | 2022 |
| Flowertheme Limited | Wholesale & retail | 2023 |
| Flowpower Limited | Energy | 2009 |
| Focal Strategy Group Limited | Financial services | 2021 |
| Focal Strategy Limited | Administrative & support | 2004 |
| Folk Interiors Ltd | Wholesale & retail | 2016 |
| Follaton Residents Association Limited | Administrative & support | 1988 |
| Folly Farm Produce Limited | Agriculture & fishing | 2017 |
| Food for Children Devon CIC | Hospitality | 2023 |
| Food in Community CIC | Hospitality | 2013 |
| Footworks Podiatry Limited | Health & social care | 2011 |
| Forge Developments S.W. Ltd | Manufacturing | 2022 |
| Forkhandles Antiques Limited | Administrative & support | 2019 |
| Forward Homes Limited | Real estate | 2021 |
| Foxhole Community Garden C.I.C. | Education | 2015 |
| Frameshift Project Ltd | Professional & scientific | 2025 |
| Frances Northrop Consulting Ltd | Professional & scientific | 2015 |
| Friends of the Dart CIC | Professional & scientific | 2024 |
| Fromthewhitehouse Ltd | Professional & scientific | 2013 |
| Fruitcake Giving Ltd | Information & communication | 2023 |
| Fungi Futures Community Interest Company | Agriculture & fishing | 2011 |
| Futurebound Ltd. | Education | 2012 |
| Futures Better Ltd | Professional & scientific | 2011 |
| G. & S. Properties Gatcombe Limited | Real estate | 2002 |
| G3Z1W2K5T Ltd | Extraterritorial | 2025 |
| Gajit Limited | Construction | 2021 |
| Galactic Space Consulting Ltd | Professional & scientific | 2025 |
| Gardentime Limited | Wholesale & retail | 2002 |
| Garner Property Cleaning & Maintenance Ltd | Construction | 2022 |
| Gate 111 Ltd | Hospitality | 2011 |
| Gate Four Ltd | Professional & scientific | 2020 |
| Gazebo Totnes Limited | Wholesale & retail | 2008 |
| GB Total Equestrian Limited | Wholesale & retail | 2018 |
| Gelos Network Limited | Arts & recreation | 2024 |
| Gemma Dudgeon Interiors Ltd | Professional & scientific | 2013 |
| Geoff Petty Limited | Education | 2004 |
| GH Project Development Limited | Agriculture & fishing | 1997 |
| Gilbert Plant & Agricultural Contractors Ltd | Administrative & support | 2007 |
| Gilboys Limited | Manufacturing | 2002 |
| Gildean Limited | Real estate | 2017 |
| Gillespie Yunnie Architects Limited | Professional & scientific | 2004 |
| Gills Nursery Driveway Ltd | Households | 2021 |
| Gimay Food Ltd | Hospitality | 2025 |
| Gladys Tidings Ltd | Arts & recreation | 2025 |
| Glebe Cottage Limited | Information & communication | 2006 |