| Shri RAM Chandra Mission UK | Health & social care | 2008 |
| Shrublands Court (Tonbridge) Limited | Real estate | 1973 |
| SHT Construction Limited | Construction | 2024 |
| Shula PR and Policy Ltd | Professional & scientific | 2022 |
| SIA Motors Ltd | Wholesale & retail | 2025 |
| Siam Forest Limited | Health & social care | 2024 |
| Sian Jarvis Associates Limited | Professional & scientific | 2024 |
| SIG and ELI Limited | Construction | 2017 |
| Sigma Cloud Solutions Limited | Information & communication | 2017 |
| Sigma Projects Capel Limited | Professional & scientific | 2014 |
| Signature Haven Limited | Real estate | 2026 |
| Signet Sunday Ltd | Wholesale & retail | 2024 |
| Sigrist Rail Electrification Services Ltd | Construction | 2019 |
| Silk and Sandalwood Lifestyle Limited | Hospitality | 2025 |
| Silva Woodfuels Ltd | Agriculture & fishing | 2011 |
| Silva Woodland Management Ltd | Agriculture & fishing | 2011 |
| Silver Leaf Developments Ltd | Real estate | 2003 |
| Silver Penguin Limited | Health & social care | 2019 |
| Silverdale Associates Ltd | Professional & scientific | 2023 |
| Silverfin Search Ltd | Information & communication | 2013 |
| Silverleaf (SA) Limited | Real estate | 2011 |
| Silverleaf 7 LLP | | 2020 |
| Silverleaf BR LLP | | 2021 |
| Silverleaf Chelsham Ltd | Real estate | 2020 |
| Silverleaf Developments Purley Ltd | Real estate | 2017 |
| Silverleaf Investments 2 LLP | | 2014 |
| Silverleaf Investments 3 LLP | | 2015 |
| Silverleaf Investments 4 LLP | | 2017 |
| Silverleaf Investments 5 LLP | | 2018 |
| Silverleaf Investments 6 LLP | | 2019 |
| Silverleaf Investments LLP | | 2014 |
| Silverleaf Land & Development LLP | | 2011 |
| Silverleaf Warlingham Ltd | Real estate | 2020 |
| Silverpark Limited | Households | 1991 |
| Silverwood Construction Inc Limited | Real estate | 2017 |
| Simla Cusine Paddock Wood Limited | Hospitality | 2019 |
| Simon Henley Contracting Limited | Information & communication | 2009 |
| Simon Horgan Ltd | Health & social care | 2020 |
| Simplix Accounting Solutions Ltd | Professional & scientific | 2022 |
| Simply Build Tonbridge Ltd | Construction | 2018 |
| Simply Clinical Ltd | Professional & scientific | 2014 |
| Simply Garden Maintenance Ltd | Administrative & support | 2017 |
| Simply Hops Ltd. | Wholesale & retail | 1972 |
| Simply Professional Governance Ltd | Education | 2023 |
| Simply Sliding Wardrobes Ltd | Manufacturing | 2015 |
| Simpson's Sounds Limited | Wholesale & retail | 2013 |
| Sims Bathrooms Ltd | Construction | 2019 |
| Sims Installations Bathrooms Ltd | Construction | 2014 |
| Sims Installations Home Improvements Ltd | Construction | 2019 |
| Sims Installations Kitchens Ltd | Construction | 2014 |
| Singha Ltd | Health & social care | 2022 |
| Sinha Medical Practice Limited | Health & social care | 2019 |
| Sirik Limited | Administrative & support | 2009 |
| Sister Nordic Ltd | Professional & scientific | 2025 |
| Site Interiors Ltd | Construction | 2017 |
| Sivolo Limited | Information & communication | 2026 |
| SIX Grosvenor Gardens Limited | Real estate | 2003 |
| SIX Media Limited | Professional & scientific | 2011 |
| SJ Law Limited | Administrative & support | 2003 |
| SJC Anaesthesia Limited | Health & social care | 2024 |
| Sjcb Investments Limited | Administrative & support | 2011 |
| SJD Construction Consultants Limited | Construction | 2015 |
| SJM Medical Limited | Health & social care | 2016 |
| Sjnr Locums Limited | Health & social care | 2012 |
| Sjqs Consultancy Ltd | Professional & scientific | 2016 |
| SJS Utilities Ltd | Professional & scientific | 2022 |
| SK Builders (Kent) Ltd | Construction | 2014 |
| SK Business Consultancy (Yorks) Ltd | Professional & scientific | 2026 |
| SK Consult Limited | Health & social care | 2016 |
| SK Square Ltd | Information & communication | 2024 |
| Skazka Cuisine Ltd | Arts & recreation | 2020 |
| Skepsis Music Limited | Arts & recreation | 2018 |
| Sketch.Stitch.Love Ltd | Wholesale & retail | 2017 |
| SKH Cardiology Limited | Health & social care | 2019 |
| Skills for Independence and Employability Limited | Education | 2019 |
| Skin and Oral Health Limited | Health & social care | 2020 |
| Skin Care Network Dermatologist LLP | | 2010 |
| Skin Fusion Limited | Health & social care | 2021 |
| Skipbox Limited | Professional & scientific | 2005 |
| Skope Property Ltd | Real estate | 2023 |
| Sky Concrete Pumping Ltd | Construction | 2024 |
| Sky Friends Limited | Professional & scientific | 2022 |
| Skybel Building Ltd | Construction | 2018 |
| Skycain Services Limited | Professional & scientific | 2024 |
| Skylark Therapy Ltd | Health & social care | 2017 |
| SL DEV Limited | Real estate | 2016 |
| Slabko Limited | Arts & recreation | 2014 |
| SLE Consultancy Services Limited | Professional & scientific | 2015 |
| Sleepy Wilson Ltd | Manufacturing | 2019 |
| Slhd Prentice Ltd | Professional & scientific | 2025 |
| Slice N' Smoke Limited | Hospitality | 2026 |
| Sllh Ltd | Financial services | 2023 |
| Sloans Creditors Partnership | | 1999 |
| Slsc Management Ltd | Wholesale & retail | 2011 |
| Smalls and Smiles Ltd | Education | 2024 |
| Smarden Place TN12 RTM Company Limited | Households | 2015 |
| Smart Arts Solutions Limited | Professional & scientific | 2008 |
| Smart Bunny Accounting Ltd | Professional & scientific | 2024 |
| Smart Marketeer Ltd | Other services | 2022 |
| Smartbiz Solutions Kent Ltd | Information & communication | 2026 |