| Duddingston Estates Limited | Real estate | 2017 |
| Durgates Lodge Ltd | Real estate | 2021 |
| Duru 6868 Ltd | Hospitality | 2026 |
| DW Axis Limited | Administrative & support | 2026 |
| DW Coaching & Consulting Ltd | Professional & scientific | 2023 |
| Dweepa UK Ltd | Health & social care | 2023 |
| DWJ Consulting Ltd | Real estate | 2010 |
| DXS Accounting Solutions Ltd | Professional & scientific | 2010 |
| Dylan LEO Stanford Ltd | Extraterritorial | 2024 |
| Dynamic Business Support Limited | Administrative & support | 2017 |
| Dynamic Waveforms Limited | Professional & scientific | 2004 |
| E & J Barrett Company Limited | Professional & scientific | 2015 |
| E C Riverside Ltd | Financial services | 2014 |
| E Design Studio Limited | Professional & scientific | 2014 |
| E Glaze Limited | Construction | 2025 |
| E M Smith Consulting Limited | Professional & scientific | 2013 |
| E&E for Readers and Authors Limited | Other services | 2022 |
| E&M (EPC) Limited | Wholesale & retail | 2008 |
| E.J.Nye Limited | Professional & scientific | 2008 |
| E.L.D Marketing Ltd | Professional & scientific | 2025 |
| E.W. Cheesman and SON Limited | Construction | 2000 |
| E.W. Tyler Trustees Limited | Administrative & support | 1965 |
| E2W Limited | Professional & scientific | 2002 |
| EA Easyfix Upkeep Ltd | Construction | 2025 |
| EAF Roofing Building and Landscaping Ltd | Construction | 2023 |
| Eageling Electrical Services Ltd | Construction | 2020 |
| Eagle Claw Houses Ltd | Real estate | 2025 |
| Eagle Property Ltd | Real estate | 2018 |
| EAI Technologies Limited | Information & communication | 2025 |
| Earthangel Projects Ltd | Professional & scientific | 2016 |
| Earthe CAP Ltd | Administrative & support | 2023 |
| Earthe Events Ltd | Administrative & support | 2023 |
| Earthe Ltd | Information & communication | 2023 |
| Earthe Tech Ltd | Administrative & support | 2023 |
| Earthstarz Ltd | Manufacturing | 2026 |
| East Central One London LLP | | 2009 |
| East House Properties Limited | Construction | 2021 |
| East London Healthcare Limited | Health & social care | 2013 |
| East Peckham M.O.T Service & Tyre Centre Limited | Wholesale & retail | 2009 |
| East Peckham Village Hall | Arts & recreation | 1998 |
| East Sussex Estates Limited | Real estate | 2002 |
| East Sussex Fire Limited | Administrative & support | 2003 |
| Easton Electrical Services Ltd | Construction | 2012 |
| Easy Co. Crowborough Ltd | Construction | 2026 |
| Easyfit Hearing Aids Limited | Wholesale & retail | 2014 |
| EAT Drink & Dance (South East) Limited | Hospitality | 2023 |
| Ebbsfleet Medicolegal Limited | Professional & scientific | 2026 |
| Ecbs Accountants Ltd | Professional & scientific | 2013 |
| Ecbs Ltd | Professional & scientific | 2017 |
| Ecis Consultants Limited | Information & communication | 1999 |
| Eclipse Doors Ltd | Construction | 2010 |
| Eco Fresh Laundry Limited | Other services | 2013 |
| Eco-Glow Aesthetics Ltd | Other services | 2024 |
| Eco-Trap Services Ltd | Administrative & support | 2025 |
| Ecochoice Properties Ltd | Professional & scientific | 2019 |
| Ecom-Kent Ltd | Wholesale & retail | 2025 |
| Economic Capital Solutions Ltd | Information & communication | 2014 |
| Economic Evaluation (London) Limited | Administrative & support | 1995 |
| Econua Limited | Wholesale & retail | 2024 |
| Ecoshine Property Care Ltd | Administrative & support | 2025 |
| Ecotherm Roofing Solutions Ltd | Administrative & support | 2017 |
| Eddies World Limited | Information & communication | 2015 |
| Eden Freehold Limited | Real estate | 2025 |
| Eden Properties (Sussex) Limited | Real estate | 2001 |
| Eden Tonbridge Limited | Hospitality | 2023 |
| Edenbridge Holiday Activities Scheme Limited | Arts & recreation | 2005 |
| Edenwood Property Services Limited | Construction | 2014 |
| Edge Diamond Services Limited | Wholesale & retail | 1974 |
| Edge MBS Ltd | Construction | 2011 |
| Edge Telematics Limited | Extraterritorial | 2018 |
| Edgefield Property & Asset Management Ltd | Real estate | 2017 |
| Edia Limited | Financial services | 2011 |
| EDO Holdings Ltd | Professional & scientific | 2026 |
| Educate Ventures Research Limited | Professional & scientific | 2020 |
| Edward Prentice Limited | Real estate | 1993 |
| Edwards Surgical Ltd | Health & social care | 2019 |
| Edwin Evans Surveyors Limited | Professional & scientific | 1992 |
| EEC Logistics (UK) Ltd | Extraterritorial | 2014 |
| EEV Properties Limited | Real estate | 2023 |
| EF (Holdings) Limited | Financial services | 2001 |
| EF Travel & Events Ltd | Other services | 2024 |
| Efak Limited | Education | 2013 |
| Effect Films Ltd | Information & communication | 2022 |
| Effective Ideas Ltd | Information & communication | 2020 |
| Eggu Limited | Information & communication | 2000 |
| Egypt House Holiday Lets Ltd | Real estate | 2021 |
| Eightoaks Limited | Professional & scientific | 2009 |
| EJL Brickwork Ltd | Construction | 2026 |
| EJP Carpentry & Joinery Ltd | Manufacturing | 2019 |
| EJP Homes Ltd | Real estate | 2026 |
| EK Structural & Civil Engineering Ltd. | Professional & scientific | 2017 |
| EKV Developments Ltd | Construction | 2023 |
| Elbe Limited | Health & social care | 2019 |
| ELC Tourism Holdings Limited | Financial services | 2021 |
| Elder Ridge Limited | Professional & scientific | 2002 |
| Elderberry Care Services (Kent) Ltd | Education | 2006 |
| Eldovet Land Limited | Real estate | 1994 |
| Eldovet Limited | Construction | 1978 |
| Eleanor Ferns Consultancy Ltd | Administrative & support | 2014 |
| Electra Jetmasks Limited | Manufacturing | 2017 |