| Start What IF Limited | Professional & scientific | 2024 |
| Station Auto Services Thirsk Limited | Wholesale & retail | 2024 |
| Steel (GC) Limited | Financial services | 2022 |
| Steel (RC) Limited | Financial services | 2022 |
| Steelstock Services (Midlands) Limited | Wholesale & retail | 2008 |
| Stefan Botma Ltd | Wholesale & retail | 2023 |
| Steven J Dresser Electrical Contractors Limited | Construction | 1999 |
| Steven J Dresser Holdings Limited | Professional & scientific | 2015 |
| Stoneybridge Limited | Hospitality | 2022 |
| Straight Shooters Limited | Arts & recreation | 2014 |
| Stress-Less Events Limited | Wholesale & retail | 2023 |
| Strive Property Holdings Ltd | Real estate | 2022 |
| Strobus Management Company Limited | Real estate | 2007 |
| Studio Extend Ltd | Professional & scientific | 2024 |
| Sturic Limited | Real estate | 2018 |
| SUE Armstrong Consultancy Ltd | Professional & scientific | 2015 |
| Sugar Therapy (T/A the Harrogate Cake Co) Ltd | Manufacturing | 2009 |
| Sun Kissed Studio Limited | Other services | 2025 |
| Sutton Hall Resort Limited | Real estate | 1982 |
| Suzyblu Limited | Wholesale & retail | 2019 |
| SW Design Group Ltd | Professional & scientific | 2017 |
| SW HV Commissioning Limited | Construction | 2020 |
| SW Property Group Ltd | Construction | 2018 |
| Swales Holdings Limited | Financial services | 2025 |
| Swaleside Accountancy Limited | Professional & scientific | 2009 |
| Swim Perfect Limited | Arts & recreation | 2010 |
| Synchronised Web Design (York) Ltd | Professional & scientific | 2021 |
| T & C Glass Limited | Real estate | 2001 |
| T G & H Harper Limited | Construction | 1994 |
| T GAS Northern Ltd | Education | 2021 |
| T-Bone & Bear Properties Ltd | Real estate | 2023 |
| T.E.D. Trading Ltd | Administrative & support | 2003 |
| Tails of Swale Limited | Other services | 2024 |
| Talking Minds Limited | Health & social care | 2023 |
| Tanuki-Ttc Ltd | Wholesale & retail | 2026 |
| Taora Holdings Ltd | Real estate | 2020 |
| Taste Tradition Holdings Limited | Financial services | 2025 |
| Taste Tradition Online Limited | Wholesale & retail | 2024 |
| Taylor Wren Limited | Wholesale & retail | 2015 |
| Tbbi Limited | Other services | 2011 |
| TD Display Ltd | Manufacturing | 2024 |
| Tea Time Yorkshire Ltd | Hospitality | 2019 |
| Team Bobsleigh Baird Limited | Arts & recreation | 2021 |
| Techknowledgy Consulting Limited | Information & communication | 2007 |
| Teddys Trove Gifts Ltd | Wholesale & retail | 2024 |
| Tempo Tactical Ltd | Manufacturing | 2022 |
| Temptec Refrigerator Hire Ltd | Administrative & support | 2025 |
| Tempus Contracts Limited | Construction | 2021 |
| Termtec Ltd | Construction | 2018 |
| THE 1911 Airport Company Limited | Transport & logistics | 2019 |
| THE Angel at Topcliffe Limited | Hospitality | 2013 |
| THE Bakehouse Yorkshire Gift Shop Limited | Wholesale & retail | 2025 |
| THE Bakehouse Yorkshire Ltd | Manufacturing | 2023 |
| THE Blue Bell at Arkendale Limited | Hospitality | 2012 |
| THE Busby Stoop Partnership LLP | | 2007 |
| THE Busy BEE Bookkeeper Ltd | Professional & scientific | 2021 |
| THE C and a, Sowerby Ltd | Hospitality | 2021 |
| THE Carbon Exchange Limited | Information & communication | 2022 |
| THE Carlton Inn Holding Company Ltd | Hospitality | 2024 |
| THE Clubhouse at Tngc Limited | Hospitality | 2025 |
| THE Coachologist Ltd | Education | 2022 |
| THE Confident Club Limited | Administrative & support | 2004 |
| THE DIVASIAN168 Ltd | Wholesale & retail | 2019 |
| THE Fishermans Fourth Wife Ltd | Hospitality | 2013 |
| THE Gold CUP Inn (Nether Silton) Ltd | Hospitality | 2025 |
| THE Great British Wagyu Company Ltd | Agriculture & fishing | 2018 |
| THE Greengrocer (Thirsk) Ltd | Wholesale & retail | 2015 |
| THE Greengrocer Yorkshire Ltd | Wholesale & retail | 2020 |
| THE Harrogate Caravan Company Ltd | Wholesale & retail | 2024 |
| THE Hide Away Lounge Limited | Hospitality | 2019 |
| THE Jolly Reno Ltd | Information & communication | 2025 |
| THE Land Exchange Ltd | Real estate | 2018 |
| THE Lavender Farm Limited | Agriculture & fishing | 2021 |
| THE Learning Barn Limited | Agriculture & fishing | 2016 |
| THE Litmous Papers Ltd. | Information & communication | 2013 |
| THE Mothership Properties Ltd | Real estate | 2019 |
| THE New Inn at Easingwold Limited | Hospitality | 2013 |
| THE Pamper Lounge (N.Yorks) Limited | Other services | 2015 |
| THE Peckish Kitchen Limited | Hospitality | 2025 |
| THE Real Petfood Company Limited | Manufacturing | 1988 |
| THE Rise'N Grind Strength DEN Ltd | Arts & recreation | 2024 |
| THE Therapy Room (Thirsk) Ltd | Health & social care | 2024 |
| THE Thirsk Hearing Practice Limited | Health & social care | 2020 |
| THE Truffled HOG Sutton Limited | Hospitality | 2025 |
| THE Tube Creation Co. Limited | Manufacturing | 2003 |
| THE Village Office Limited | Real estate | 2000 |
| THE Visitor Centre (Kirby Wiske) Ltd | Arts & recreation | 2012 |
| THE Whitestonecliff Inn Ltd | Hospitality | 2020 |
| THE Whitestonecliffe Inn Ltd | Hospitality | 2026 |
| THE Wildlife Haven Rescue and Rehabilitation Centre | Professional & scientific | 2013 |
| THE Yorkshire Storage Company Ltd | Real estate | 2025 |
| THE Zowie Wellness Ltd | Extraterritorial | 2023 |
| Therapy Labs International Ltd | Hospitality | 2025 |
| These Four Walls Investments Limited | Real estate | 2021 |
| These Four Walls Investments SA Ltd | Real estate | 2024 |
| Thirkleby Hall Cottages Management Limited | Households | 2020 |
| Thirkleby Hall Management Company Limited | Households | 2003 |
| Thirsk & District Motor Club Limited | Other services | 1981 |
| Thirsk Birds of Prey Centre Ltd | Arts & recreation | 2012 |
| Thirsk Bodyshop & Service Centre Limited | Wholesale & retail | 2010 |