| Dash Couriers (Wiltshire) Ltd | Transport & logistics | 2020 |
| Davakin Ltd | Construction | 2025 |
| Dave Parsons Accountancy Limited | Professional & scientific | 2020 |
| Dave Parsons Accounting Limited | Professional & scientific | 2020 |
| Davey Hunt Properties Limited | Real estate | 2024 |
| David Chappell Design Limited | Manufacturing | 1997 |
| David Collard & Co Limited | Professional & scientific | 2024 |
| David Croxton Limited | Agriculture & fishing | 1981 |
| David Grant Building Limited | Construction | 2011 |
| David Mahon Limited | Health & social care | 2019 |
| David Marks Carpets Limited | Wholesale & retail | 2014 |
| David Perry | | 1991 |
| David Wells Heating & Plumbing Limited | Construction | 2009 |
| Davidson & Co. Talent Agents Ltd | Professional & scientific | 2023 |
| Davies Family Ltd | Hospitality | 2023 |
| Davies-Uk Limited | Financial services | 2021 |
| Davis & Barrett Brickwork Contractors Limited | Construction | 2007 |
| Davis & Barrett Scaffolding Contractors Limited | Construction | 2019 |
| Davis and Barrett Business Management Ltd | Financial services | 2016 |
| Davis and Barrett Property Investment Limited | Real estate | 2021 |
| Dawn Booth Life Coach Ltd | Education | 2024 |
| Dawnhaze Limited | Real estate | 2001 |
| Dawson and Killen Ltd | Real estate | 2015 |
| Day & Night Interiors Ltd | Wholesale & retail | 2023 |
| DAY1 Communications Limited | Professional & scientific | 2002 |
| DB Advisors Limited | Professional & scientific | 2015 |
| DB UK Investments Ltd | Financial services | 2025 |
| Dbdplay Ltd | Administrative & support | 2014 |
| DBH Flooring Ltd | Construction | 2021 |
| DC Carpenters Ltd | Manufacturing | 2022 |
| DCA Education Ltd | Education | 2023 |
| Dcec Cernwood | Financial services | 2025 |
| DCG Holdings Ltd | Real estate | 2015 |
| DCG Utility Services Limited | Construction | 2018 |
| DD Property SW Limited | Real estate | 2023 |
| DD Stars Ltd | Other services | 2023 |
| DDC Gardener's Ltd | Other services | 2025 |
| DDD South West Limited | Professional & scientific | 2008 |
| Ddlm Ltd | Health & social care | 2021 |
| Dd’S Bright Cleaning Services Limited | Administrative & support | 2024 |
| DE Hond Financial Services Ltd | Financial services | 2003 |
| DE Kroon Consultancy Ltd | Administrative & support | 2007 |
| DE Lepago Ltd | Administrative & support | 2026 |
| DE Novo Risk Solutions Limited | Financial services | 2016 |
| DE Raaf Beheer Limited | Professional & scientific | 2012 |
| DE Sousa Properties Limited | Real estate | 2019 |
| Dean Court Business Partnership Limited | Real estate | 2016 |
| Dean Stevenson Engineering Limited | Extraterritorial | 2015 |
| Deane Drive RTM Company Limited | Households | 2009 |
| Deanegate Trustees Limited | Professional & scientific | 2014 |
| Deborah Parker Ltd | Professional & scientific | 2021 |
| Debs Empire Limited | Health & social care | 2023 |
| DEC Plumbing & Heating Ltd | Construction | 2025 |
| Decisive Retail Ltd | Wholesale & retail | 2022 |
| Deelis Roofing Limited | Construction | 2017 |
| Deepsale Limited | Professional & scientific | 1996 |
| Deershaw Ltd | Financial services | 2025 |
| Deeveeo Company Limited | Administrative & support | 2023 |
| Defend Fire Systems Limited | Construction | 2026 |
| Defiant Media Ltd | Information & communication | 2021 |
| Delamere Residents Company Limited | Households | 1987 |
| Delatt Limited | Professional & scientific | 2017 |
| Delivery Direct Logistics Limited | Transport & logistics | 2003 |
| Dell Electrics Ltd | Energy | 2023 |
| Delmark Investments Limited | Real estate | 2020 |
| Delomic Holdings Ltd | Financial services | 2019 |
| Delony Limited | Professional & scientific | 2011 |
| Delos IT Solutions Limited | Information & communication | 2016 |
| Delphi Wellness Clinic Ltd | Health & social care | 2024 |
| Delphis Projects Limited | Professional & scientific | 2023 |
| Delta Marine Engineering Limited | Professional & scientific | 2017 |
| Dembpic Limited | Financial services | 2018 |
| Denborne Limited | Real estate | 1990 |
| Denbury Care Limited | Health & social care | 2025 |
| Dendron Holdings Limited | Financial services | 2023 |
| Dene Business Park Limited | Real estate | 2022 |
| Denergy Limited | Construction | 2015 |
| Denine Limited | Real estate | 2025 |
| Dennis Clothier & Sons Limited | Agriculture & fishing | 1990 |
| Denzil Property Management Ltd | Real estate | 2025 |
| Deos Consultancy Limited | Health & social care | 2015 |
| Dera's Healthcare Limited | Health & social care | 2025 |
| Dermatology Education Group Ltd | Health & social care | 2024 |
| Dermes Medical Ltd | Health & social care | 2025 |
| Dermody Coaching Limited | Education | 2022 |
| Dermody-Steer Developments Limited | Real estate | 2019 |
| Derry FD Services Ltd | Professional & scientific | 2012 |
| Design Compliance Ltd | Administrative & support | 2016 |
| Design Hub Ltd | Information & communication | 2023 |
| Design Twelve Ltd | Information & communication | 2012 |
| Designerds Limited | Professional & scientific | 2011 |
| Detillen Property LLP | | 2025 |
| Develon Ltd | Real estate | 2024 |
| Development Land Promotion Ltd | Real estate | 2022 |
| Devon & Somerset Contractors Limited | Agriculture & fishing | 2017 |
| Devon & Somerset Eggs Holdings Ltd | Financial services | 2025 |
| Devon & Somerset Eggs Ltd | Agriculture & fishing | 2023 |
| Devon County Sports Ltd | Wholesale & retail | 2010 |
| Devon Home Improvements Limited | Construction | 2003 |
| Devon Railway Centre Limited | Arts & recreation | 2006 |