| DOT Healthcare Limited | Health & social care | 2015 |
| Double O ME Ltd | Information & communication | 2013 |
| Double Plusss Company Ltd | Other services | 2024 |
| Doublefour Healthcare Limited | Health & social care | 2025 |
| Doubler Composites Limited | Manufacturing | 2025 |
| Doug Kendall Consulting Ltd. | Professional & scientific | 2013 |
| Douglas Research Limited | Information & communication | 2022 |
| Dovalley Ltd | Information & communication | 2025 |
| Dove Technologies Limited | Professional & scientific | 2019 |
| Dovecote Barns Limited | Real estate | 2022 |
| Dovetail Building Limited | Construction | 2015 |
| Down to Earth Garden Supplies Ltd | Wholesale & retail | 2017 |
| Down to Earth Swindon Ltd | Households | 2024 |
| Downend Flooring & Tiling Limited | Construction | 1997 |
| Downers Management Limited | Arts & recreation | 2016 |
| Downing Street Properties Ltd | Real estate | 2018 |
| Downlands Consulting Limited | Professional & scientific | 2021 |
| Downtown Sports Ltd | Wholesale & retail | 2026 |
| Doxford International Management Company Limited | Real estate | 1992 |
| Doyle & Barnes Associates Ltd | Professional & scientific | 2019 |
| DP Trucking Ltd | Transport & logistics | 2017 |
| Dpatras Transport Ltd | Transport & logistics | 2017 |
| DPB Groundwork Ltd | Construction | 2021 |
| Dpds Architecture Limited | Professional & scientific | 1994 |
| DPM Heating and Plumbing Limited | Construction | 2013 |
| DPR Transport Services Limited | Transport & logistics | 2008 |
| DR Controls Engineering Ltd | Professional & scientific | 2017 |
| DR Fashion Club Limited | Wholesale & retail | 2025 |
| DR Intelligent Solutions Ltd | Administrative & support | 2024 |
| DR JAS Ltd | Health & social care | 2024 |
| DR Singh Medics Private Ltd | Health & social care | 2025 |
| DR. Fouda Limited | Health & social care | 2014 |
| DR. K Todorov Ltd | Health & social care | 2012 |
| DR6 Limited | Information & communication | 2015 |
| DRA Property Services Limited | Construction | 2015 |
| Dragon Lore Tours Ltd | Administrative & support | 2025 |
| Dragon SIP Distillers Ltd | Manufacturing | 2024 |
| Dragonstone Property Group Ltd | Households | 2026 |
| Dragos Courier Ltd | Transport & logistics | 2020 |
| Drain Depot Ltd | Wholesale & retail | 2008 |
| Drain Help Ltd | Water & waste | 2021 |
| Dratec Limited | Information & communication | 2023 |
| Draughts Tech Ltd | Information & communication | 2022 |
| Drawoh Ltd | Other services | 2014 |
| Draycot Flight Centre Limited | Transport & logistics | 2009 |
| Draycott Football Academy Ltd | Other services | 2017 |
| Draycott Homes Limited | Real estate | 2017 |
| Draycott Sports Camp Ltd | Arts & recreation | 2014 |
| Draycott Storage Ltd | Transport & logistics | 2026 |
| Dream Prime Project Ltd | Real estate | 2026 |
| Dreamdent Ltd | Health & social care | 2024 |
| Dreamin Kennels Limited | Agriculture & fishing | 2026 |
| Dreamline Group (UK) Ltd | Wholesale & retail | 2019 |
| Dreams on the Wall Building Services Ltd | Construction | 2023 |
| Dreams Property Ventures Ltd | Real estate | 2025 |
| Dredge-It Ltd | Information & communication | 2014 |
| Dress My Windows SN25 Limited | Wholesale & retail | 2019 |
| Dressability | Health & social care | 2003 |
| Drew Design Consultants Ltd | Information & communication | 2026 |
| DRF Enterprises Ltd | Information & communication | 2004 |
| Drip DAD Ltd | Manufacturing | 2025 |
| Drip Media Ltd | Information & communication | 2010 |
| Driver ID Digital Technologies Ltd | Information & communication | 2025 |
| Driving With Lycia Ltd | Education | 2025 |
| Drni Properties Ltd | Real estate | 2024 |
| Dronecore Limited | Administrative & support | 2025 |
| Drop of Water Cleaning & Maintenance Ltd | Water & waste | 2025 |
| Drove Estates Limited | Construction | 2022 |
| Drove Road 1964 Limited | Extraterritorial | 2014 |
| Drove Veterinary Hospital Limited | Professional & scientific | 2015 |
| Drowsy Sleep Co Ltd | Manufacturing | 2020 |
| Drum Key Ltd | Information & communication | 2015 |
| Drumlin Property Services Limited | Professional & scientific | 2018 |
| Drummond Education Ltd | Administrative & support | 2011 |
| Dryfesdale Property Ltd | Real estate | 2025 |
| Drytree Limited | Wholesale & retail | 2024 |
| DRZ Motors Ltd | Wholesale & retail | 2025 |
| DS Consulting Solutions Ltd | Professional & scientific | 2024 |
| DS Exotic CPD Limited | Education | 2025 |
| DS Lettings Ltd | Real estate | 2019 |
| DSD Valets Ltd | Wholesale & retail | 2025 |
| DSF777 Ltd | Hospitality | 2025 |
| DSM Build & Design Limited | Construction | 2025 |
| Dsny Wealth Planning Limited | Professional & scientific | 2021 |
| DSP Foods Ltd | Hospitality | 2025 |
| DSP Living Ltd | Real estate | 2026 |
| DSP Motors Limited | Wholesale & retail | 2020 |
| DST Assets Ltd | Real estate | 2025 |
| Dsthomes Ltd | Hospitality | 2024 |
| DSV Courier Services Ltd | Transport & logistics | 2023 |
| DSW Auto Group Ltd | Manufacturing | 2018 |
| DT Couriers Ltd | Transport & logistics | 2022 |
| DT Property Assets Ltd | Real estate | 2020 |
| DT Property Works Limited | Real estate | 2016 |
| DT Vent Ltd | Construction | 2025 |
| DTB05 Ltd | Hospitality | 2022 |
| DTC Shipping and Logistics Ltd. | Transport & logistics | 2016 |
| DTD Motor Traders Limited | Wholesale & retail | 2026 |
| Dtee Ltd | Information & communication | 2002 |
| DTG Cleaning Service Ltd | Administrative & support | 2024 |