| Dazzlenshazzle Limited | Manufacturing | 2026 |
| DB Construction (Midlands) Limited | Construction | 2026 |
| DBI Property Development Limited | Construction | 2025 |
| Dbweston Ltd | Real estate | 2021 |
| DCI Architecture Limited | Professional & scientific | 2003 |
| DCS Transport Midlands Limited | Transport & logistics | 2019 |
| DE Real Goodnews Ltd | Wholesale & retail | 2025 |
| De-Luxe (Burton) Ltd | Transport & logistics | 2008 |
| Dealmead Limited | Construction | 1975 |
| Dean Vincent Ltd | Wholesale & retail | 2026 |
| Deasta Limited | Real estate | 2024 |
| Deddington Grange Management Company Limited | Households | 2017 |
| Defence LAB Self Protection Limited | Public administration | 2019 |
| Dehaney OT Limited | Health & social care | 2025 |
| DEL BOY Enterprises Ltd | Wholesale & retail | 2018 |
| Delboy's Ltd | Wholesale & retail | 2021 |
| Delladawson Ltd | Professional & scientific | 2025 |
| Dellner Limited | Manufacturing | 2005 |
| Deluxe Booths Limited | Professional & scientific | 2023 |
| Demons Detailing Ltd | Administrative & support | 2025 |
| Densy Developments Limited | Construction | 2004 |
| Dent - Training, Education and Development Limited | Education | 2008 |
| Derby Performance Hose Ltd | Manufacturing | 2010 |
| Derby Trans Ltd | Transport & logistics | 2025 |
| Derbyshire Flooring Group Limited | Construction | 2026 |
| Design and Pave Landscapes Limited | Construction | 2006 |
| Designphase Ltd | Construction | 2014 |
| DEV Realty Ltd | Construction | 2026 |
| Dexim Limited | Information & communication | 1986 |
| DGM Plumbing & Heating (Midlands) Limited | Construction | 2021 |
| DH Construction Solutions Ltd | Construction | 2019 |
| DH Training Limited | Education | 2021 |
| Diamond Nails 198 Ltd | Other services | 2025 |
| Digitech Engineering Ltd | Professional & scientific | 2026 |
| Discount Food Limited | Wholesale & retail | 2025 |
| District Maintenance Ltd | Construction | 2025 |
| Dita Car Transportation Ltd | Transport & logistics | 2023 |
| Divineclothinguk Ltd | Wholesale & retail | 2024 |
| Divineukclothing Ltd | Wholesale & retail | 2025 |
| Dixie Sidings (Burton) Management Company Limited | Households | 2018 |
| Dixon Engineering (Midlands) Limited | Manufacturing | 2026 |
| Dixonn Limited | Wholesale & retail | 2025 |
| DIY Dogs Play Limited | Other services | 2020 |
| DJK Pubs Ltd | Hospitality | 2025 |
| DKG Rigging & Lifting Services Ltd | Professional & scientific | 2019 |
| DL Accountancy Limited | Professional & scientific | 2010 |
| DL Maintenance Engineering Ltd | Professional & scientific | 2025 |
| DL Scada Solutions Ltd | Professional & scientific | 2026 |
| DLH Consultancy Limited | Information & communication | 2025 |
| DM Property Associates Ltd | Real estate | 2018 |
| Dogs Play Limited | Other services | 2020 |
| Dolo Food Co Ltd | Manufacturing | 2018 |
| Domelec Ltd | Construction | 2008 |
| Donisthorpe Auto Services Ltd | Wholesale & retail | 2022 |
| Donisthorpe Community Interest Company | Arts & recreation | 2021 |
| Don’T Shoot the Messenger Ltd | Public administration | 2022 |
| Doocas Ltd | Hospitality | 2020 |
| Doorly Ltd | Administrative & support | 2025 |
| Dormer Woods Management Company Limited | Households | 2018 |
| Double R Network Group Ltd | Financial services | 2019 |
| Dove Grange (Hilton) Management Company Limited | Households | 2003 |
| Dove Valley Homes Limited | Construction | 2020 |
| Dovedale Catering & Events Limited | Hospitality | 2013 |
| Dpf-Professionals Ltd | Wholesale & retail | 2024 |
| DPG Composites Ltd | Manufacturing | 2021 |
| DPM Services (Midlands) Limited | Manufacturing | 2016 |
| DR Lisa Lloyd - Clinical Psychology Services Limited | Health & social care | 2023 |
| Dr's K Patel Ltd | Professional & scientific | 2023 |
| Draga Fire Protection Ltd | Construction | 2018 |
| Draga Passive Fire Protection Ltd | Construction | 2020 |
| Draga Passive Fire Stopping Ltd | Construction | 2025 |
| Dragon Parc Management Company Limited | Households | 2025 |
| Drausa Ltd | Education | 2019 |
| Dream Builders Ltd | Construction | 2019 |
| Dreamcore Entertainment Limited | Wholesale & retail | 2022 |
| Driveconnect by Alin Ltd | Transport & logistics | 2026 |
| DRM Plumbing and Electrical Ltd | Energy | 2019 |
| DS Kitchen Installations Ltd | Construction | 2019 |
| DTF 16 Ltd | Professional & scientific | 2025 |
| Duart Holdings Limited | Real estate | 1986 |
| DUB Unit Ltd | Wholesale & retail | 2026 |
| Dubbin Dayz Ltd | Other services | 2019 |
| Dunn Translations Limited | Professional & scientific | 2020 |
| Dunrich Limited | Wholesale & retail | 2000 |
| Dunstall Process Engineers Limited | Manufacturing | 2014 |
| Duratusuk Ltd | Other services | 2019 |
| DW Midlands Electrical Limited | Energy | 2018 |
| Dwfm Properties Ltd | Professional & scientific | 2023 |
| DWP Business Group Limited | Transport & logistics | 2020 |
| DWP Department Stores Ltd | Wholesale & retail | 2021 |
| DWP Warehousing & Storage Ltd | Transport & logistics | 2023 |
| DXN Handrail Products Limited | Manufacturing | 2026 |
| Dyluxe Ltd | Wholesale & retail | 2021 |
| Dynamix Bar and Events Ltd | Hospitality | 2013 |
| D’Lux Beauty by Samantha Ltd | Other services | 2025 |
| E Cooper Property Services Limited | Real estate | 2023 |
| E L Collective Ltd | Financial services | 2026 |
| E.M Property Group Ltd | Real estate | 2022 |
| Eades Place Residents Management Company Limited | Households | 2014 |
| Eagle Park Management Company Limited | Real estate | 2017 |