| Stenson Cleaning Limited | Administrative & support | 2003 |
| Stepforwardhousing Ltd | Real estate | 2017 |
| Stephanie Bennett Coaching Ltd | Professional & scientific | 2021 |
| Stephanie Butt Photography Limited | Professional & scientific | 2016 |
| Stephanie Phair Consulting Ltd | Professional & scientific | 2025 |
| Stepping UP Ltd | Professional & scientific | 2023 |
| Sterge Developments Ltd | Real estate | 2022 |
| Sterge Property Group Ltd | Real estate | 2021 |
| Sterling Advocates Limited | Professional & scientific | 2016 |
| Sterling BCM Limited | Administrative & support | 2017 |
| Sterling Crest Facilities Management Ltd | Administrative & support | 2026 |
| Steve Gilbert UK Limited | Professional & scientific | 2023 |
| Steve Hagan & Sons Ltd | Construction | 2015 |
| Steve Morris & SON LLP | | 2024 |
| Steve's Transport Limited | Transport & logistics | 2009 |
| Steven G. Eddie Accountants Limited | Professional & scientific | 2016 |
| Steven G. Eddie Business Services Ltd. | Professional & scientific | 1989 |
| Steven G. Eddie Ltd. | Professional & scientific | 2015 |
| Steven Hale Hearing Limited | Wholesale & retail | 2006 |
| Stibbs Haulage Limited | Transport & logistics | 2019 |
| Stirlin Business Park Management Company Limited | Real estate | 2016 |
| Stirling Green Consulting Ltd | Information & communication | 2025 |
| Stirling Green Property Ltd | Real estate | 2021 |
| Stirling Interiors Limited | Manufacturing | 2021 |
| Stokes Estates Limited | Real estate | 2022 |
| Stone Development Studio Limited | Construction | 2022 |
| Stone Property Limited | Real estate | 2015 |
| Stone Strong Construction Ltd | Construction | 2024 |
| Stonebridge Health Group Ltd | Education | 2026 |
| Stonefield Limited | Real estate | 2023 |
| Stoneleigh Property Investments UK Limited | Real estate | 2022 |
| Stonewall Investments Limited | Professional & scientific | 1969 |
| Stonewick Ltd | Professional & scientific | 2013 |
| Stonewood SW Ltd | Construction | 2011 |
| Stonewood Developments SW Limited | Construction | 2022 |
| Stoneworks Building Services Ltd | Construction | 2024 |
| Storage Wizard Limited | Transport & logistics | 2015 |
| Storas Urlair Ltd | Professional & scientific | 2023 |
| Storeflex Limited | Real estate | 2026 |
| Storm Cloud Networks Ltd | Information & communication | 2010 |
| Story Comms Holdings Limited | Financial services | 2019 |
| Story Comms Limited | Professional & scientific | 2014 |
| Storylabs Creative Ltd | Professional & scientific | 2023 |
| Stowood Midlands Limited | Real estate | 2026 |
| Stradoak Limited | Health & social care | 2024 |
| Strateg Asset Management Limited | Financial services | 2013 |
| Strategic Payments Consulting Limited | Professional & scientific | 2025 |
| Strategic Property Solutions Ltd | Real estate | 2024 |
| Stratford Court (Freeholders) Limited | Households | 2016 |
| Stratford Gift Company Limited | Wholesale & retail | 2012 |
| Stratford Investments Partnership (Southern) LLP | | 2024 |
| Stratford Waterfront Management Company Limited | Real estate | 2019 |
| Strathpine Limited | Wholesale & retail | 2024 |
| Strattons of Worcestershire Limited | Wholesale & retail | 2009 |
| Strawberry Hills Leisure Ltd | Wholesale & retail | 2011 |
| Strawberry Print.Com Ltd | Manufacturing | 2011 |
| Streathers Carpentry & Construction Ltd | Manufacturing | 2020 |
| Street Art Advertising Ltd | Arts & recreation | 2011 |
| Street Barber Europe Ltd | Other services | 2024 |
| Street Katz Theatre and Film CIC | Information & communication | 2020 |
| Streetly Book-Keeping & Accountancy Services Ltd | Professional & scientific | 2002 |
| Streetly Commercial Repairs Ltd | Wholesale & retail | 2010 |
| Streetly Commercial Services Ltd | Wholesale & retail | 2026 |
| Streetly Construction Ltd | Construction | 2019 |
| Streetly Dementia Support Group CIC | Financial services | 2025 |
| Streetly Furnishings Limited | Wholesale & retail | 1999 |
| Streetly Healthcare Limited | Other services | 2016 |
| Streetly Lawn Tennis Club Limited(The) | Arts & recreation | 1927 |
| Streetly Tanning Ltd | Wholesale & retail | 2026 |
| Streetly Vets Ltd | Professional & scientific | 2015 |
| Streetly Village Fish Bar Ltd | Hospitality | 2014 |
| Stretton House Management Co. Limited | Households | 1989 |
| Stride Flooring Ltd | Construction | 2026 |
| Stridez Limited | Professional & scientific | 2009 |
| Stripes and Graphics Automotive Ltd | Manufacturing | 2023 |
| Strugurel Ltd | Transport & logistics | 2018 |
| Strut Limited | Extraterritorial | 1982 |
| Strutweld UK Ltd | Manufacturing | 2019 |
| Strysen Heating Limited | Construction | 2012 |
| STS Services Limited | Manufacturing | 2002 |
| Stuart Reeve Consulting Limited | Information & communication | 2015 |
| Student Spaces Birmingham Limited | Real estate | 2016 |
| Studenti Ltd | Administrative & support | 2024 |
| Studio DMP Limited | Administrative & support | 2008 |
| Studio Landscape Limited | Wholesale & retail | 2019 |
| Studio Products Hub Ltd | Professional & scientific | 2016 |
| Studio RBA Ltd. | Professional & scientific | 2017 |
| STUDIO2STAGE Ltd | Wholesale & retail | 2023 |
| Stump Animations Ltd | Information & communication | 2023 |
| Stunn Consulting Ltd | Professional & scientific | 2012 |
| Stunn Developments Ltd | Real estate | 2021 |
| Sturgess Locum Solutions Ltd | Health & social care | 2021 |
| Sturry Road Holdings (UK) Limited | Administrative & support | 2017 |
| STW Vehicle Solutions Ltd | Professional & scientific | 2025 |
| Style Earth Holdings Ltd | Financial services | 2026 |
| Style Earth Ltd | Administrative & support | 2015 |
| Style of Substance Ltd | Construction | 2018 |
| Styled by RAJ Limited | Other services | 2022 |
| Stylish Radiators Limited | Wholesale & retail | 2003 |
| Subete Properties Limited | Real estate | 2022 |