| Dowsett & Jenkins Limited | Extraterritorial | 1914 |
| Doyle Transport Ltd | Transport & logistics | 2017 |
| DP Restorations Ltd | Construction | 2023 |
| DP Solutions Ltd | Professional & scientific | 2007 |
| Dpey Group Limited | Administrative & support | 2017 |
| DQS Property Solutions Ltd | Real estate | 2026 |
| DR B K Singh Surgery GPF Limited | Professional & scientific | 2013 |
| DR Chandan Associates Limited | Health & social care | 2020 |
| DR Construction WM Ltd | Construction | 2026 |
| DR Deepak Sharma Limited | Health & social care | 2026 |
| DR Drew a Thompson Management UK Ltd | Wholesale & retail | 2024 |
| DR Faisel Limited | Health & social care | 2014 |
| DR HAQ Healthcare Services Ltd | Health & social care | 2013 |
| DR James Halpern Ltd | Health & social care | 2017 |
| DR Khedr Limited | Health & social care | 2025 |
| DR KT Limited | Health & social care | 2021 |
| DR Lucinda Aesthetics Ltd | Health & social care | 2025 |
| DR Lucky Psychology Limited | Health & social care | 2021 |
| DR Manjit R Kaur Ltd | Health & social care | 2011 |
| DR R Dubb Limited | Health & social care | 2008 |
| DR Sahdev Ltd | Health & social care | 2023 |
| DR Seema Aesthetics Ltd | Health & social care | 2023 |
| DR Sekhon Skin & Facial Aesthetics Ltd | Health & social care | 2019 |
| DR Shivani Aesthetics Ltd | Health & social care | 2025 |
| DR. Sheikh Ltd | Health & social care | 2022 |
| DRA Engineering Ltd | Professional & scientific | 2019 |
| Dragon Vapour Ltd | Wholesale & retail | 2017 |
| Dragonverse Ltd | Information & communication | 2022 |
| Draigfi Ltd | Information & communication | 2025 |
| Draw PUB Company Limited | Hospitality | 2018 |
| Drayford Property Limited | Real estate | 2022 |
| Dream Clean Commercial Ltd | Administrative & support | 2025 |
| Dreambuildsolutions Ltd | Construction | 2016 |
| Drej Holdings Ltd | Real estate | 2017 |
| Drighlington Ltd | Transport & logistics | 2022 |
| Drillfield Engineering Co,Limited | Manufacturing | 1962 |
| Drink Your Fruit Limited | Wholesale & retail | 2010 |
| Drinkstop Limited | Wholesale & retail | 1995 |
| Drive in Days Ltd | Other services | 2016 |
| Drive Mobility (Droitwich Spa) Ltd | Wholesale & retail | 2026 |
| Drive Mobility Ltd | Wholesale & retail | 2026 |
| Drive Van Hire Ltd | Administrative & support | 2025 |
| Driveway Restoration Solutions Ltd | Administrative & support | 2016 |
| Droitwich Spa Fish Bar Limited | Hospitality | 2018 |
| Dronetagadventure Ltd | Administrative & support | 2026 |
| DRP Agencies Limited | Wholesale & retail | 2001 |
| DRR Foods Ltd | Hospitality | 2023 |
| Drsn Associates Limited | Construction | 2021 |
| Drsn Building Maintenance Ltd | Construction | 2026 |
| Drummond Lettings Ltd | Real estate | 2020 |
| DRY Hydraulic Solutions Ltd | Wholesale & retail | 2015 |
| Dryblue Limited | Hospitality | 2024 |
| Drysure Outdoor Limited | Manufacturing | 2015 |
| DRZ Locums Ltd | Health & social care | 2015 |
| DS Products Limited | Wholesale & retail | 2011 |
| DSA Investment Properties Ltd | Real estate | 2026 |
| DSG Architecture Limited | Professional & scientific | 2018 |
| Dsox Ltd | Professional & scientific | 2022 |
| DSP Property Services Limited | Real estate | 2016 |
| DSS Ltd | Professional & scientific | 2018 |
| DSW Services Limited | Professional & scientific | 2016 |
| Dual Logistic Midlands Ltd | Transport & logistics | 2023 |
| Dubb & Sons Investments Limited | Real estate | 2016 |
| Dubb Property Enterprises Limited | Real estate | 2026 |
| Duck&Duck Ltd | Financial services | 2021 |
| Dudley Capital Limited | Real estate | 2024 |
| Dumoge Limited | Health & social care | 2024 |
| Dunavolve Consulting Ltd | Professional & scientific | 2025 |
| Dunkley Associates Ltd | Real estate | 2020 |
| Dunn Installations & Fabrications Limited | Construction | 2018 |
| Dunne Creative Ltd | Professional & scientific | 2026 |
| Dunning (Undertaking) Limited | Extraterritorial | 1989 |
| Dunton Barkside Retreat Ltd | Other services | 2025 |
| Duoprysm Limited | Real estate | 2021 |
| Duplicut Limited | Administrative & support | 2009 |
| Duriozy Ltd | Transport & logistics | 2023 |
| Durkin Property Ltd | Real estate | 2018 |
| Duro Climate Design Ltd | Energy | 2016 |
| Dustrywareds Ltd | Administrative & support | 2021 |
| DVD Construction Limited | Construction | 2025 |
| DVR1 Ltd | Transport & logistics | 2025 |
| DW Music Services Ltd | Arts & recreation | 2003 |
| Dwarfish Tales Ltd | Wholesale & retail | 2026 |
| Dwivedi Medical Limited | Health & social care | 2018 |
| Dxwx Ltd | Real estate | 2019 |
| DYA Kids Limited | Wholesale & retail | 2023 |
| Dydzimiux Ltd | Transport & logistics | 2023 |
| Dymond & Dymond Limited | Professional & scientific | 2002 |
| Dynamic Design Solutions Ltd | Professional & scientific | 2025 |
| Dynamic Investment Group Ltd | Real estate | 2025 |
| Dynamic Solutions Support Ltd | Professional & scientific | 2012 |
| Dynamix Inventions UK Limited | Professional & scientific | 2024 |
| Dynamixa Management Limited | Households | 2002 |
| Dynasty Medical LLP | | 2012 |
| Dyson Media Ltd | Information & communication | 2009 |
| Dyson Richards Limited | Extraterritorial | 1925 |
| E & a Property 24 Ltd | Real estate | 2024 |
| E & G Fisheries Limited | Hospitality | 2017 |
| E & P Solutions Ltd | Transport & logistics | 2019 |
| E Choice Consulting Limited | Administrative & support | 2003 |