| RGB Media Ltd | Information & communication | 2011 |
| RGN Financial Planning Ltd | Financial services | 2010 |
| RGN Systems Limited | Information & communication | 2025 |
| RGY Construction Ltd | Construction | 2026 |
| RH Consulting Management Ltd | Professional & scientific | 2020 |
| RHE Solutions Limited | Information & communication | 2014 |
| Rheal Superfoods Ltd | Wholesale & retail | 2017 |
| Rich Properties NE Ltd | Real estate | 2025 |
| Richard Beston Designs Limited | Other services | 2013 |
| Richard Brown Consultant Limited | Professional & scientific | 2013 |
| Richard Farndon Limited | Manufacturing | 2015 |
| Richard Foreman Engineering & Consultancy Limited | Professional & scientific | 2016 |
| Richard Jamie Prater Ltd | Extraterritorial | 2024 |
| Richard Reed (Holdings) Limited | Professional & scientific | 2017 |
| Richard Reed Ltd | Professional & scientific | 2006 |
| Richards Cleaning and Washrooms Services Limited | Administrative & support | 2004 |
| Richards Management Consultants Ltd | Information & communication | 2014 |
| Richardson's News and Balloons Limited | Wholesale & retail | 2013 |
| Richm Enterprise Limited | Health & social care | 2026 |
| Richwood 1881 Limited | Wholesale & retail | 2020 |
| Richy's Sales & Services Limited | Wholesale & retail | 2021 |
| Rider Properties Ltd | Real estate | 2026 |
| Rigel Trans Ltd | Transport & logistics | 2024 |
| Rigging RAT Limited | Construction | 2017 |
| Ringtone Phone Company Ltd | Information & communication | 2021 |
| Ringtone Plant Hire Limited | Administrative & support | 2021 |
| Risali Consultancy Services Limited | Information & communication | 2013 |
| Risk & Governance Services Limited | Professional & scientific | 2016 |
| Risk of Bear Limited | Professional & scientific | 2016 |
| Ritchie Electrical & Inspection Services Limited | Construction | 2015 |
| Ritesh & Vijna Ltd | Health & social care | 2017 |
| Ritevalue Ltd | Professional & scientific | 2012 |
| River 2 Reef Aquatics Ltd | Wholesale & retail | 2019 |
| River Industrial Services & Engineering Limited | Extraterritorial | 1988 |
| River Tees Engineering & Welding Ltd. | Energy | 1984 |
| Riverbank Leisure Limited | Hospitality | 2015 |
| Rivergreen Foods Limited | Manufacturing | 2019 |
| Riverking Recycling Ltd | Water & waste | 2009 |
| Riverside Consulting Community Interest Company | Professional & scientific | 2008 |
| Riverside Deli Ltd | Hospitality | 2025 |
| Riverside Scaffolding Ltd | Construction | 2021 |
| Riverside Stone Ltd | Wholesale & retail | 2018 |
| Riverstone Wealth Management Limited | Financial services | 2009 |
| Riverview Kitchen Durham Limited | Hospitality | 2017 |
| Riverview Surgery Limited | Health & social care | 2011 |
| Rizlabs Limited | Wholesale & retail | 2025 |
| RJ Property Services NCL Ltd | Construction | 2023 |
| RJC Group NE Ltd | Construction | 2026 |
| Rjohal Retailers Limited | Wholesale & retail | 2026 |
| RK2K Developments Ltd | Professional & scientific | 2026 |
| RKA Leisure Ltd | Hospitality | 2013 |
| RLD Property Holdings Limited | Real estate | 2025 |
| RLL Blade Services Limited | Energy | 2020 |
| RM & Co Accountancy Ltd | Professional & scientific | 2011 |
| RMA Construction Solutions Ltd | Construction | 2015 |
| Road 2 Recruitment Ltd | Information & communication | 2016 |
| Roal Pizza Sunderland Ltd | Hospitality | 2025 |
| Roane Retrofit Services Limited | Other services | 2026 |
| Roar Motion Ltd | Information & communication | 2016 |
| ROB Lawson Education Ltd | Education | 2023 |
| ROB Lawson Ltd | Professional & scientific | 2012 |
| Rob.Marshall Inspection Services Ltd | Professional & scientific | 2013 |
| Robbie Electrical Services Ltd | Manufacturing | 2015 |
| Robby Ltd | Hospitality | 2016 |
| Robdj Leisure Ltd | Hospitality | 2026 |
| Robert J Davis Ltd | Construction | 2025 |
| Robert Miller & Company (Cleadon) Limited | Professional & scientific | 2008 |
| Robertson Interiors Ltd | Wholesale & retail | 2024 |
| Robertson Smith Ltd | Wholesale & retail | 2019 |
| Robinson Damp Proofing Northeast Ltd | Construction | 2026 |
| Robinson Property NE Ltd | Real estate | 2024 |
| Robinsons Freight Services Ltd | Transport & logistics | 2024 |
| Robson Miiller Homes Ltd | Construction | 2025 |
| ROC Innovations Ltd | Real estate | 2025 |
| Rocean Basket (NE) Ltd | Hospitality | 2019 |
| Rocean Basket (SR) Ltd | Hospitality | 2025 |
| Rock Lodge Trustees Limited | Administrative & support | 2005 |
| Rock Property Developments Ltd | Real estate | 2024 |
| Rockbottom Limited | Wholesale & retail | 2024 |
| Rockstar Finance Ltd | Financial services | 2021 |
| Roco (Events Management) Limited | Administrative & support | 2013 |
| Rodgers Property Company Limited | Real estate | 2025 |
| ROK Architecture Ltd | Professional & scientific | 2021 |
| Roker (Property) Developments Ltd | Construction | 2008 |
| Roker Car Wash Ltd | Administrative & support | 2023 |
| Roker Electric Ltd | Energy | 2022 |
| Roker Events Ltd | Hospitality | 2024 |
| Roker Fisheries Ltd | Hospitality | 2023 |
| Roker Hospitality Group Ltd | Real estate | 2025 |
| Roker Investments Limited | Wholesale & retail | 2024 |
| Roker PIE Shop Limited | Hospitality | 2022 |
| Roker Pier Heritage Group Community Interest Company | Arts & recreation | 2016 |
| Roker Records Ltd | Wholesale & retail | 2025 |
| Roker Shelter Ltd | Hospitality | 2019 |
| Rokers Barbers Ltd | Other services | 2025 |
| Rokshaw Limited | Professional & scientific | 2012 |
| Rollador Shutters Limited | Manufacturing | 2014 |
| Roma Restaurant Limited | Hospitality | 2003 |
| Romeo Ventures Limited | Financial services | 2015 |
| Ronabeth Baguioro Ltd | Health & social care | 2018 |