| Cohousing Development Company Ltd | Households | 2024 |
| Cohousing Exeter Limited | Households | 2025 |
| Cole Crispin Limited | Construction | 2014 |
| Coleman Jones Limited | Professional & scientific | 2013 |
| Colin Thom Plumbing & Heating Limited | Construction | 2001 |
| Collective Energy Ltd | Administrative & support | 2025 |
| Collective Supplies Co Ltd | Wholesale & retail | 2026 |
| Collingridge Employment Law Ltd | Administrative & support | 2014 |
| Colour Counsellors Limited | Other services | 1970 |
| Colourful Catering Limited | Hospitality | 2019 |
| Colwell and Ford Gardens LLP | | 2018 |
| Comfy Cotswolds Ltd | Hospitality | 2024 |
| Commercial Polished Concrete Floors Ltd | Manufacturing | 2019 |
| Common Goal Limited | Professional & scientific | 2009 |
| Common Works Architecture Ltd | Professional & scientific | 2025 |
| Commons LAB | Professional & scientific | 2026 |
| Commpassion Ltd | Professional & scientific | 2011 |
| Community Library in Painswick | Arts & recreation | 2012 |
| Community Opportunity | Wholesale & retail | 2017 |
| Community Outreach Consultancy Limited | Other services | 2009 |
| Community Waters CIC | Arts & recreation | 2023 |
| Comotion Communities CIC | Administrative & support | 2025 |
| Compassionate Revolution Xrbtc Ltd | Professional & scientific | 2023 |
| Complete Aerospace Limited | Professional & scientific | 2017 |
| Complete Energy Consultancy Ltd. | Professional & scientific | 2009 |
| Compliance Management Limited | Manufacturing | 2019 |
| Comusense Limited | Information & communication | 2026 |
| Confident Collective Limited | Financial services | 2019 |
| Confident Learning Limited | Education | 2009 |
| Connect Electrical & AV Ltd | Construction | 2022 |
| Connected Leadership Limited | Professional & scientific | 2012 |
| Connection Carpentry Ltd | Construction | 2021 |
| Conquistare Ltd | Hospitality | 2024 |
| Consent Denied Ltd | Other services | 2025 |
| Construct by Design Limited | Construction | 2021 |
| Construct Cotswolds Ltd | Construction | 2026 |
| Construction A.S.H Limited | Construction | 2025 |
| Content Structures Ltd | Professional & scientific | 2024 |
| Cook Property Developments Ltd | Construction | 2021 |
| Cooke Technical Limited | Professional & scientific | 2018 |
| Cooksey Consultancy (Nailsworth) Limited | Professional & scientific | 2021 |
| Cooksey Consultancy Limited | Information & communication | 2016 |
| Coopers Building & Maintenance Ltd | Construction | 2011 |
| Cope Sales & Marketing Ltd. | Professional & scientific | 2013 |
| Coraly Space Ltd | Information & communication | 2025 |
| Core Geotechnics Ltd | Professional & scientific | 2008 |
| Corin Hughes Limited | Professional & scientific | 2011 |
| Cornerstone Commercial Ltd | Real estate | 2013 |
| Cornerstone Entertainment Ltd. | Arts & recreation | 2018 |
| Cornerstones Consulting Ltd | Professional & scientific | 2013 |
| Corpmerch Ltd | Wholesale & retail | 2026 |
| Cosmic Yard Limited | Information & communication | 2026 |
| Costello and Hellerstein Ltd | Manufacturing | 2018 |
| Cotswold & Cavendish Care Group Limited | Professional & scientific | 2013 |
| Cotswold Abode Management Ltd | Hospitality | 2024 |
| Cotswold Accountancy Ltd | Professional & scientific | 2019 |
| Cotswold Appliances (Oxford) Limited | Wholesale & retail | 2009 |
| Cotswold Autos Ltd. | Wholesale & retail | 2019 |
| Cotswold Beacon Academy Trust | Education | 2011 |
| Cotswold Builds Limited | Construction | 2024 |
| Cotswold Bunnies Nurseries Ltd | Education | 2016 |
| Cotswold C2C Ltd | Construction | 2013 |
| Cotswold Canals Trust (Trading) Limited | Wholesale & retail | 1994 |
| Cotswold Car Company Stroud Ltd | Wholesale & retail | 2023 |
| Cotswold Carpentry & Construction Ltd | Construction | 2020 |
| Cotswold Catering Limited | Construction | 1998 |
| Cotswold Chiropractic and Massage Clinic Limited | Health & social care | 2018 |
| Cotswold Clay Club Ltd | Arts & recreation | 2021 |
| Cotswold Cleaning Services Ltd | Administrative & support | 2022 |
| Cotswold Commercials Ltd | Wholesale & retail | 2020 |
| Cotswold Cookery School Limited | Education | 2008 |
| Cotswold Digital Solutions Limited | Information & communication | 2017 |
| Cotswold Ecology Ltd | Professional & scientific | 2018 |
| Cotswold Gliding Club Limited | Arts & recreation | 2018 |
| Cotswold Heating Solutions Ltd | Professional & scientific | 2018 |
| Cotswold Heritage Joinery Ltd | Construction | 2026 |
| Cotswold House Care Home Limited | Health & social care | 1992 |
| Cotswold Hs&E Ltd | Professional & scientific | 2021 |
| Cotswold Lime Pointing Limited | Construction | 2017 |
| Cotswold Locks & Glazing Ltd | Construction | 2026 |
| Cotswold Maintenance Ltd | Construction | 2013 |
| Cotswold Meat Direct Limited | Agriculture & fishing | 2020 |
| Cotswold Motor Park Ltd | Wholesale & retail | 2024 |
| Cotswold Music Tutors Limited | Education | 2014 |
| Cotswold Oakwood Limited | Construction | 2026 |
| Cotswold Organics Ltd | Wholesale & retail | 2018 |
| Cotswold Quantity Surveying Limited | Professional & scientific | 2012 |
| Cotswold Research and Consultancy Ltd | Education | 2018 |
| Cotswold Spa Ltd | Other services | 2021 |
| Cotswold Sporting Ltd | Wholesale & retail | 2019 |
| Cotswold Stone Floor Cleaners Ltd | Households | 2013 |
| Cotswold Timber Structures Limited | Construction | 2024 |
| Cotswold Upper Crust Limited | Wholesale & retail | 2002 |
| Cotswold Valley Kitchens Limited | Manufacturing | 2023 |
| Cotswold Valleys Building Surveying Ltd | Professional & scientific | 2026 |
| Cotswold Vending Services Limited | Hospitality | 2013 |
| Cotswold Way Scaffolding Limited | Construction | 2022 |
| Counsell Pubs Limited | Hospitality | 2007 |
| Country Rooms Limited | Hospitality | 2024 |
| Country Rooms Property Limited | Real estate | 2024 |