| Farah and Arif Limited | Real estate | 2012 |
| Farfield Manor Limited | Professional & scientific | 2002 |
| Farmach Ltd | Real estate | 2009 |
| Farnham Tech Ltd | Information & communication | 2025 |
| Farrah Rose Events Ltd | Other services | 2021 |
| Fascialift Upvc Maintenance Ltd | Construction | 2013 |
| Fashejer Motors Ltd | Wholesale & retail | 2021 |
| Fast Autocare North East Ltd | Wholesale & retail | 2016 |
| Fast Track Cover Limited | Financial services | 2013 |
| Fast Track Energy Limited | Other services | 2016 |
| Fast Track Oceanic Limited | Administrative & support | 2019 |
| Fatjackropes Ltd | Construction | 2025 |
| Faulkner Enterprises Ltd | Administrative & support | 2021 |
| FCL Investment Holdings Limited | Financial services | 2024 |
| FE Parker Limited | Wholesale & retail | 2017 |
| FEB Energy Services Ltd | Professional & scientific | 2023 |
| Fedcap Employment Limited | Education | 2019 |
| Fedcap Insynergy Limited | Administrative & support | 1989 |
| Fedcap UK | Education | 2016 |
| Feed My Health Limited | Education | 2023 |
| Femina Healthcare Ltd | Health & social care | 2023 |
| Fergie Leisure Ltd | Wholesale & retail | 2018 |
| Ferguson Industrial Services Limited | Construction | 2015 |
| Fern Paving & Landscape Builders Ltd | Administrative & support | 2020 |
| Ferreira Property Sourcing Ltd | Real estate | 2026 |
| Ferrotec Inspection Ltd | Professional & scientific | 2011 |
| Festival of Thrift CIC | Arts & recreation | 2015 |
| Feuermoor Limited | Manufacturing | 2025 |
| Fhbuilder Ltd | Education | 2023 |
| FHW Elec Ltd | Construction | 2025 |
| Fibox (UK) Limited | Extraterritorial | 1996 |
| Fibox Limited | Manufacturing | 1996 |
| Fightfest Ltd | Arts & recreation | 2024 |
| Fika & Co (Norton) Limited | Hospitality | 2025 |
| Finaegis Ltd | Professional & scientific | 2023 |
| Finance Solutions NE Limited | Financial services | 2025 |
| Finding Families Limited | Information & communication | 2022 |
| Findit Group Ltd | Information & communication | 2025 |
| Finesse French Polishing Ltd | Professional & scientific | 2016 |
| Finishing Touches NE Limited | Wholesale & retail | 2025 |
| Finishing Touches SR Limited | Wholesale & retail | 2025 |
| Finneys Luxury Lodges Limited | Hospitality | 2026 |
| Finnie Engineering & Technology Limited | Professional & scientific | 2024 |
| Fionda Lettings Ltd | Real estate | 2019 |
| Fire & Flour Ltd | Hospitality | 2020 |
| Fireside Ltd | Information & communication | 2022 |
| First Cloud Solutions Limited | Information & communication | 2018 |
| First Light Home Solutions Ltd | Construction | 2026 |
| First Phase Electric Services Ltd | Administrative & support | 2015 |
| First Real Estate Limited | Real estate | 2018 |
| First Sight Estates Limited | Hospitality | 2009 |
| Fitfactory Technology Ltd | Information & communication | 2006 |
| Fitness 22 Group Limited | Arts & recreation | 2022 |
| Fitness 22 Personal Training Limited | Education | 2020 |
| Fitt Property Developments Limited | Real estate | 2024 |
| Five Star Services NE Ltd | Administrative & support | 2023 |
| Fixera Limited | Professional & scientific | 2006 |
| FK Medical Services Ltd | Health & social care | 2020 |
| FL Asbestos Environmental Ltd | Construction | 2026 |
| Flaat Housing Teesside Limited | Real estate | 2021 |
| Flamborough Holiday Homes Limited | Real estate | 2020 |
| Flanplan Ltd | Professional & scientific | 2025 |
| Flavourforge Ltd | Hospitality | 2025 |
| Flavours Sandwiches & Desserts Ltd | Hospitality | 2026 |
| Fleet Recruitment Limited | Administrative & support | 2014 |
| Fleetgo Telematics Ltd | Other services | 2008 |
| Flex Flow Studio Ltd | Arts & recreation | 2024 |
| Flexible Workforce Limited | Administrative & support | 2005 |
| Flexion Health & Fitness Ltd | Information & communication | 2019 |
| Flexncare Limited | Administrative & support | 2022 |
| Flexteam UK Ltd | Administrative & support | 2003 |
| Floggit and Scarper Ltd | Professional & scientific | 2025 |
| Florcraft Professional Contract Flooring Limited | Construction | 2007 |
| Floridian Mechanical Services Ltd | Construction | 2026 |
| Flourish and Flair Limited | Wholesale & retail | 2025 |
| Flowerhouse (NE) Ltd | Wholesale & retail | 2010 |
| Flux Property Investors Ltd | Real estate | 2020 |
| Flux Serviced Accommodation Ltd | Real estate | 2020 |
| FMI Minecraft Management Ltd | Professional & scientific | 2020 |
| Fnmh Ltd | Transport & logistics | 2025 |
| Foam for Comfort Limited | Wholesale & retail | 1979 |
| Food to Go (North East) Limited | Wholesale & retail | 2018 |
| Foodfirst Saltburn CIC | Hospitality | 2022 |
| FOR the Love of Reading Ltd | Information & communication | 2020 |
| Fore Logistics Ltd | Transport & logistics | 2017 |
| Forest Friends Childcare Ltd | Education | 2018 |
| Forest Friends Childcare Redcar Ltd | Education | 2021 |
| Formleaf Limited | Professional & scientific | 2009 |
| Formtec Commercial Services Ltd | Construction | 2025 |
| Fortis K9 Ltd | Administrative & support | 2025 |
| Fortyfore Consultancy Limited | Financial services | 2019 |
| Forward Edge Ltd | Professional & scientific | 2010 |
| Forward Innovations Technologies Ltd | Information & communication | 2026 |
| Foster Laws & Company Limited | Manufacturing | 1967 |
| Found North East Ltd | Education | 2025 |
| Foundations 2 Property Co. Ltd | Real estate | 2026 |
| Four Paws Plaza Ltd | Hospitality | 2024 |
| Four Pillars Finance Ltd | Financial services | 2026 |
| Four Seasons Food Services (NE) Ltd | Wholesale & retail | 2015 |
| Four Winds Lakenheath Limited | Real estate | 2025 |