| Rose Water Lane Interiors Limited | Construction | 2025 |
| Rosella Investments Limited | Professional & scientific | 2003 |
| Rosen Enterprises Limited | Wholesale & retail | 2017 |
| Roses Strategists Ltd | Information & communication | 2026 |
| Rosewood Construction Herts Limited | Other services | 2017 |
| Rosha Property Ltd | Real estate | 2019 |
| Rosie Helen Ltd | Arts & recreation | 2023 |
| Rosie Shackleton Solutions Ltd | Professional & scientific | 2024 |
| Ross Railways Ltd | Construction | 2025 |
| Ross Randall Plumbing & Heating Limited | Construction | 2013 |
| Rosters Recruitment Ltd | Other services | 2014 |
| Rotariu Building Services Limited | Construction | 2018 |
| Rotok Design Limited | Professional & scientific | 2006 |
| Rouan Limited | Professional & scientific | 2013 |
| Roubier Ltd | Manufacturing | 2024 |
| Round Pizza Ltd | Hospitality | 2025 |
| Routes to Success Consultancy Ltd | Professional & scientific | 2024 |
| Rowe Studio Ltd | Information & communication | 2023 |
| Roxa Consultancy Ltd | Professional & scientific | 2022 |
| Roxa Teamwear Limited | Wholesale & retail | 2010 |
| Roxanne Kent Speech Therapy Ltd | Health & social care | 2026 |
| Royston Roofing Ltd | Construction | 2019 |
| Royston Vehicle Services Limited | Wholesale & retail | 2004 |
| RP Health Limited | Health & social care | 2012 |
| RPM Care Services Ltd | Administrative & support | 2017 |
| Rptw PUB Limited | Hospitality | 2019 |
| Rqps Services Ltd | Real estate | 2014 |
| RR Group Worldwide Ltd | Transport & logistics | 2026 |
| RRA Inspections Ltd | Construction | 2023 |
| Rrezaie-E Ltd | Information & communication | 2022 |
| RRK Entertainment Ltd | Arts & recreation | 2019 |
| RRT Estates Limited | Real estate | 2023 |
| RS Healthcare Ltd. | Health & social care | 2015 |
| RS Payments Limited | Information & communication | 2025 |
| RSCARE247 Limited | Health & social care | 2025 |
| RSL Housing Ltd | Real estate | 2026 |
| RSL Property Developments Limited | Administrative & support | 2016 |
| RSL Property Holdings Limited | Administrative & support | 2016 |
| RST Civils Ltd | Construction | 2019 |
| RST Medical Limited | Health & social care | 2025 |
| Ru's Corner Tradings Ltd | Wholesale & retail | 2024 |
| Rubber Glove Productions Limited | Information & communication | 2014 |
| Rubbish Clearance Hertfordshire Ltd | Water & waste | 2022 |
| Rubern Limited | Health & social care | 2014 |
| Ruder Wakenings Ltd | Real estate | 2021 |
| Rudi Tech Ltd | Information & communication | 2022 |
| Rudo Ltd | Health & social care | 2022 |
| Ruggieri Holdings Limited | Financial services | 2021 |
| Runwell Group Ltd | Professional & scientific | 2023 |
| Rushmore Films Limited | Information & communication | 2024 |
| Rushton Atlantic Limited | Extraterritorial | 2008 |
| Rushton Energy Limited | Extraterritorial | 2008 |
| Rushton Group Ltd | Administrative & support | 2015 |
| Rushton International Limited | Administrative & support | 1997 |
| Russia Court Management Limited | Households | 1988 |
| Rusu Construction Ltd | Construction | 2025 |
| Ruwa Properties Ltd. | Real estate | 2018 |
| RW Residential Investments Limited | Real estate | 2026 |
| Rwhr Ltd | Administrative & support | 2022 |
| Rwpc Associates Limited | Other services | 2014 |
| Ryan Farley Consulting Ltd | Administrative & support | 2025 |
| Ryan Gregory Holdings Limited | Financial services | 2022 |
| Ryan Gregory Limited | Administrative & support | 2017 |
| Rydor 63 Limited | Extraterritorial | 2013 |
| RYO Consulting Ltd | Professional & scientific | 2018 |
| Rype Tonics Limited | Administrative & support | 2014 |
| Ryse Holdings Ltd | Wholesale & retail | 2026 |
| S & D QA Services Limited | Administrative & support | 2007 |
| S & G Robinson Properties Limited | Real estate | 2019 |
| S & H Rigging Limited | Construction | 2013 |
| S & J Brock Builders Limited | Construction | 2021 |
| S & K Consultants Ltd | Professional & scientific | 2023 |
| S a C Groundwork Ltd | Construction | 2021 |
| S C Duncan Stevenage Ltd | Construction | 2020 |
| S C Taylor Consultancy Limited | Information & communication | 2017 |
| S D C Performance (UK) Ltd. | Real estate | 2008 |
| S G Hitchin Limited | Arts & recreation | 2017 |
| S G Webb & SON Engineering Limited | Professional & scientific | 2007 |
| S J Fire Limited | Public administration | 2013 |
| S K a Enterprises Limited | Arts & recreation | 2009 |
| S K Pharma Consultancy Limited | Professional & scientific | 2017 |
| S Koop Building & Plastering Services Limited | Construction | 2018 |
| S M Scenery Ltd | Manufacturing | 2019 |
| S R B Rewinds Holdings Limited | Other services | 2016 |
| S R Motor Services Limited | Wholesale & retail | 2002 |
| S W K Rigging Limited | Construction | 2022 |
| S Willis Felt Roofing Limited | Construction | 2022 |
| S&F Entertainment Limited | Arts & recreation | 2022 |
| S&J Fencing Ltd | Construction | 2021 |
| S&P Tech Ventures Limited | Information & communication | 2026 |
| S&R Property Care Ltd | Construction | 2019 |
| S&S Property & Garden Maintenance Ltd | Construction | 2025 |
| S. Keene Autos Limited | Wholesale & retail | 1994 |
| S.A Remapping & Performance Ltd | Wholesale & retail | 2023 |
| S.A.L.T Intl Limited | Professional & scientific | 2022 |
| S.P.S. Specialist Protection Services Limited | Administrative & support | 1999 |
| S.T.S. 2000 Ltd. | Administrative & support | 1997 |
| S.Thenu Limited | Wholesale & retail | 2018 |
| SA Engineering Limited | Professional & scientific | 2008 |
| SA Foodyz Ltd | Hospitality | 2025 |