| Sarah Harvey Design Limited | Professional & scientific | 2012 |
| Saramacca Capital Limited | Professional & scientific | 2025 |
| Sarawa Limited | Administrative & support | 2008 |
| Sarem Health Ltd | Wholesale & retail | 2026 |
| Sarita Allison Limited | Arts & recreation | 2015 |
| Sarju Solutions Limited | Information & communication | 2023 |
| Sarkan Limited | Real estate | 2023 |
| Sarnell Properties Limited | Construction | 1973 |
| Sarova Properties Ltd | Real estate | 2015 |
| Sarthi Mart Limited | Wholesale & retail | 2026 |
| Saru Makaan Limited | Real estate | 2017 |
| Sarvoday Estates Limited | Real estate | 2023 |
| SAS Data Services Limited | Information & communication | 2005 |
| Sascron Digital Limited | Wholesale & retail | 2024 |
| Sassy Social Ltd | Professional & scientific | 2019 |
| Sasta Manufacturing Co Limited | Real estate | 1944 |
| SAT Universe Ltd | Information & communication | 2010 |
| Sathiya Private Ltd | Wholesale & retail | 2023 |
| Satson Trading Ltd | Wholesale & retail | 2008 |
| Satya Tech Ltd | Wholesale & retail | 2014 |
| Saudi Gourmet Limited | Extraterritorial | 2016 |
| Saul Coaching Ltd | Professional & scientific | 2022 |
| Saunders & Taylor Cabling Limited | Professional & scientific | 1997 |
| SAV Ventures Ltd | Manufacturing | 2026 |
| Save Hertsmere Ltd | Professional & scientific | 2021 |
| Save Radlett Ltd | Professional & scientific | 2021 |
| Saviana Limited | Education | 2018 |
| Savouries International Ltd | Manufacturing | 2020 |
| Savoy Developers LLP | | 2019 |
| Savoy Estates Limited | Real estate | 2015 |
| Savoy Grove LLP | | 2017 |
| Savoy Place SPV 2 Limited | Real estate | 2025 |
| Savoy Place SPV Limited | Real estate | 2024 |
| Savoy Products Limited | Wholesale & retail | 2024 |
| Savoy Projects LLP | | 2015 |
| Savoy Real Estate Limited | Real estate | 2020 |
| Savyy Tech Limited | Wholesale & retail | 2020 |
| Sawan Shah Ltd | Education | 2015 |
| Sayan Solutions Ltd | Professional & scientific | 2018 |
| SB Carbon Ltd | Wholesale & retail | 2018 |
| SBC Consultancy Services Limited | Professional & scientific | 2025 |
| Scaffold Inspections Ltd | Other services | 2017 |
| Scaffoldblend Ltd | Administrative & support | 2025 |
| Scala Global Limited | Real estate | 2005 |
| Scalability AI Ltd | Information & communication | 2026 |
| Scale UP Media Ventures Ltd | Professional & scientific | 2020 |
| Scaleupgym Limited | Education | 2025 |
| Scalingtime Ltd | Wholesale & retail | 2026 |
| Scarsdale Consultancy Limited | Professional & scientific | 2013 |
| Scarsdale Holdings Limited | Professional & scientific | 2021 |
| Scary Ghost Promotions Ltd | Arts & recreation | 2025 |
| School of Badges Limited | Wholesale & retail | 2025 |
| Schwar & Co Limited | Wholesale & retail | 1990 |
| Schwarzthal Tech Ltd | Information & communication | 2020 |
| Scntrum Services Ltd | Administrative & support | 2023 |
| Scoll Methods Limited | Information & communication | 1994 |
| Scoop Retail Technologies Limited | Other services | 2015 |
| Scorpion Properties & Investments Ltd | Real estate | 2018 |
| Scotch Bonnet Limited | Professional & scientific | 2025 |
| Scriptio Publishing Ltd | Information & communication | 2022 |
| Scrum Pack Ltd | Administrative & support | 2021 |
| Scuderia Lusso Ltd | Extraterritorial | 2016 |
| Scumble Limited | Arts & recreation | 2023 |
| Scuro Properties Limited | Administrative & support | 2012 |
| Sdaks Consultancy Ltd | Professional & scientific | 2024 |
| SDJ Estates Limited | Extraterritorial | 2013 |
| SDL Contractors Limited | Construction | 2024 |
| Sdlt Rebate 4 U Ltd | Administrative & support | 2024 |
| SDN Investments Ltd | Real estate | 2025 |
| Sea Investments (North) Limited | Real estate | 2019 |
| Sea Investments Limited | Real estate | 2013 |
| Sea Island Impact Ltd | Professional & scientific | 2025 |
| Sea Valeting Ltd | Wholesale & retail | 2024 |
| Seacross Productions Ltd | Information & communication | 2026 |
| Sealed Honey Spoon Limited | Manufacturing | 2025 |
| Search NO More Ltd | Wholesale & retail | 2021 |
| Seasons Landscapes Limited | Other services | 2004 |
| Sebastian Moldovan Limited | Other services | 2017 |
| Sebastian NB Builders Ltd | Construction | 2022 |
| Second Chance Plus Ltd | Education | 2013 |
| Secondary Entrance Ltd | Education | 2017 |
| SED Renewables Ltd | Construction | 2021 |
| SED Verde Ltd | Water & waste | 2020 |
| Sedas Strategic Land Holdings Ltd | Real estate | 2022 |
| Sedas Strategic Land Ltd | Real estate | 2022 |
| Seedhars Taekwondo Schools Limited | Arts & recreation | 2014 |
| Seetalent Limited | Professional & scientific | 2024 |
| Sefia London Ltd | Wholesale & retail | 2017 |
| Sehgal Amoros Ventures Limited | Financial services | 2020 |
| Sekhon Transport Services Ltd | Transport & logistics | 2025 |
| Sekula Special Educational Services Limited | Education | 2024 |
| Selby Group Ltd | Real estate | 2015 |
| Select 365 Consultancy Ltd | Information & communication | 2025 |
| Select Drive Ltd | Other services | 2016 |
| Select GB Limited | Wholesale & retail | 2008 |
| Selectx Holdings Limited | Information & communication | 2024 |
| Selectx Limited | Professional & scientific | 2003 |
| Self Publish BE Happy Ltd | Administrative & support | 2011 |
| SELFMADE101 Ltd | Wholesale & retail | 2022 |
| Sellico Limited | Wholesale & retail | 2014 |