| Summer Naturals Limited | Wholesale & retail | 2014 |
| Sumo Circle Limited | Arts & recreation | 2009 |
| Sunflower Stalybridge Ltd | Education | 2013 |
| Sunrays Travels Ltd | Administrative & support | 2024 |
| Sunseeker Blinds Ltd | Extraterritorial | 2014 |
| Sunshine and Soul Studio Ltd | Other services | 2023 |
| Sure Facilities Limited | Other services | 2009 |
| SW Machinery Services Ltd | Manufacturing | 2009 |
| Swan Quality Control Ltd | Construction | 2014 |
| Sweet Crystals Ltd | Wholesale & retail | 2023 |
| Sweet Food Limited | Hospitality | 2025 |
| Swollen APE Tattoo Ltd | Arts & recreation | 2026 |
| Symmetry Medical Aesthetics Ltd | Other services | 2025 |
| Systems, Automation & Monitoring Ltd | Construction | 2024 |
| T K Utilities Ltd | Construction | 2022 |
| T Mcquillan Motor Engineers Limited | Administrative & support | 2011 |
| T S Warehousing and Distribution Solutions Ltd | Transport & logistics | 2023 |
| Tacti Coach Limited | Other services | 2024 |
| Take 1 Scenic Services Limited | Information & communication | 2010 |
| Talbot Aviation Limited | Manufacturing | 2019 |
| Tamber Surveying Ltd | Professional & scientific | 2025 |
| Tameside Accident Repair Centre Limited | Administrative & support | 2002 |
| Tameside BA Services Limited | Information & communication | 2019 |
| Tameside Caravans Ltd | Wholesale & retail | 2003 |
| Tameside Elite Boxing Academy CIC | Arts & recreation | 2025 |
| Tameside Fire Protection Services Limited | Other services | 2001 |
| Tameside Scale Services Limited | Manufacturing | 2010 |
| Tameside's Magical Maids Limited | Administrative & support | 2026 |
| Tannerz Northwest Ltd | Other services | 2025 |
| Tarri Ltd | Hospitality | 2022 |
| Taxlocker Ltd | Financial services | 2025 |
| TCA Invest Ltd | Real estate | 2020 |
| TCA Investment Holdings Ltd | Real estate | 2020 |
| TDD Landscapes Limited | Administrative & support | 2024 |
| Technostock Limited | Wholesale & retail | 2014 |
| Techxone Ltd | Other services | 2019 |
| Tehe Gifts Ltd | Wholesale & retail | 2019 |
| Terminal Development Ltd | Information & communication | 2017 |
| Terracasa Ltd | Real estate | 2022 |
| Teta Ltd | Hospitality | 2023 |
| Tetras Hospitality Ltd | Hospitality | 2018 |
| Tfif Club Limited | Construction | 2021 |
| Tfps (Holdings) Limited | Professional & scientific | 2008 |
| THE Accountancy People Manchester Ltd | Professional & scientific | 2011 |
| THE Adams Overland Company Ltd | Wholesale & retail | 2023 |
| THE Bath Company (Manchester) Ltd | Wholesale & retail | 2021 |
| THE Beauty Project HQ Limited | Education | 2023 |
| THE Bella Leigh Company Limited | Other services | 2022 |
| THE Cheer LAB Ltd | Arts & recreation | 2020 |
| THE Clinic (MCR) Ltd | Health & social care | 2023 |
| THE Coopers Court Property Management Company Limited | Households | 2018 |
| THE Cornerroom Limited | Information & communication | 2019 |
| THE Cottage Delicatessen Limited | Wholesale & retail | 2017 |
| THE Crafters Shop Limited | Manufacturing | 2019 |
| THE Crafty KEG Brewery Ltd | Manufacturing | 2025 |
| THE Cremation Group Ltd | Other services | 2020 |
| THE Dutchy Project CIC | Health & social care | 2023 |
| THE Edge of the Deep Green Sea Limited | Hospitality | 2018 |
| THE Foodie Marketing Company Ltd | Information & communication | 2023 |
| THE Goal League Ltd | Arts & recreation | 2015 |
| THE Hampden Partnership Limited | Professional & scientific | 2015 |
| THE Hawthorn Gallery Limited | Wholesale & retail | 2009 |
| THE Ivory Lounge BH Limited | Other services | 2023 |
| THE Laboratory Partnership Ltd | Health & social care | 2021 |
| THE Lash LAB MCR NW Ltd | Other services | 2024 |
| THE Laundrette Ltd | Other services | 2023 |
| THE Mahal Restaurant Ltd | Hospitality | 2025 |
| THE Manchester Plumbers Ltd | Construction | 2018 |
| THE Ministry of Inspiration Limited | Education | 2003 |
| THE MR2 Drivers' Club Limited | Other services | 1994 |
| THE Nail Lounge (Lees) Ltd | Other services | 2025 |
| THE Nail Lounge (Uppermill) Limited | Education | 2020 |
| THE New Stalybridge Labour Club Limited | Hospitality | 2016 |
| THE Old Oak Management Company Limited | Households | 2023 |
| THE Old Thirteenth Cheshire Astley Volunteer Rifleman Corps Inn Ltd | Hospitality | 2019 |
| THE Online Marketing Group Ltd | Information & communication | 2013 |
| THE Power of Resilience CIC | Education | 2022 |
| THE Property Ladder NW Limited | Real estate | 2004 |
| THE Raven Product Stewardship Services Ltd | Professional & scientific | 2024 |
| THE Sealantco Ltd | Wholesale & retail | 2025 |
| THE Sound of the Snug Limited | Information & communication | 2026 |
| THE Staffing Company Ltd | Administrative & support | 2023 |
| THE Stalybridge Community Club and Kitchen CIC | Hospitality | 2023 |
| THE Summerhouse Studio Ltd | Manufacturing | 2020 |
| THE Talent Consortium Ltd | Administrative & support | 2018 |
| THE Thrive Store Ltd | Wholesale & retail | 2025 |
| THE Vape Tavern Ltd | Wholesale & retail | 2018 |
| THE Yoga Family Ltd | Arts & recreation | 2017 |
| Thomas Cole Search Ltd | Administrative & support | 2022 |
| Thomas James Associates Limited | Information & communication | 2011 |
| Thomas James Developments Limited | Construction | 2024 |
| Thomas James Property Group Limited | Real estate | 2018 |
| Thomas James Property Investments Limited | Real estate | 2021 |
| Thomas James Property Services Limited | Hospitality | 2018 |
| Thomasent PVT Ltd | Health & social care | 2025 |
| Thorfire Ltd | Administrative & support | 2011 |
| Thrive With Jojo Ltd | Administrative & support | 2026 |
| Thynkspace Limited | Information & communication | 2017 |
| Tier 1 Battery Storage Ltd | Professional & scientific | 2024 |
| Tiger City Services (Lancashire) Limited | Professional & scientific | 2012 |