| D West & Sons Maintenance Ltd | Construction | 2007 |
| D&A Air Conditioning Ltd | Energy | 2011 |
| D&F Security Services Limited | Administrative & support | 2021 |
| D'Arcy Davis & Co Ltd | Construction | 2022 |
| D'Arcy Soar Consultancy Services Limited | Real estate | 1995 |
| D'Arcy Soar Limited | Real estate | 1993 |
| DAC Ssas Limited | Financial services | 2017 |
| DAC Trustee Holdings Limited | Extraterritorial | 2024 |
| Daisy Designs Bespoke Stationery Ltd | Manufacturing | 2017 |
| DAL Brickwork Ltd | Construction | 2009 |
| DAL Homes Ltd | Construction | 2025 |
| Dallas Groundworks Limited | Construction | 2017 |
| Danas Virtual Office Ltd. | Administrative & support | 2021 |
| Dansty Limited | Wholesale & retail | 2021 |
| Daria Euro Trans Ltd | Transport & logistics | 2019 |
| Dasha Paradoks Ltd | Arts & recreation | 2024 |
| Data Infrastructure Solutions Ltd | Information & communication | 2012 |
| Datacentre Consultancy Services Ltd | Professional & scientific | 2023 |
| DAV Industrial Safety & Security Solutions Ltd | Information & communication | 2023 |
| Davenport Minerals Ltd | Mining & quarrying | 2026 |
| Davey Grover Consultancy Limited | Professional & scientific | 2014 |
| David Polhill Engineering Services Limited | Construction | 2019 |
| Davidson Roberts Properties Limited | Hospitality | 2022 |
| Davies Design Consultancy Ltd | Professional & scientific | 2023 |
| Davies Stone Garden Buildings Ltd | Manufacturing | 2022 |
| Day to Day Grocery Delivery Limited | Other services | 2023 |
| Dazncolwheels Limited | Wholesale & retail | 2017 |
| Dbqp Holding Ltd | Administrative & support | 2020 |
| Dce-Int Limited | Information & communication | 2014 |
| De.Solo Ltd | Real estate | 2021 |
| Deals Kingdom Ltd | Wholesale & retail | 2018 |
| Dean Parcel Limited | Transport & logistics | 2018 |
| Delphine Dubuisson Ltd | Wholesale & retail | 2020 |
| Delta-Othala Ltd | Extraterritorial | 2021 |
| Demmetrix Ltd | Other services | 2018 |
| Denson Developments Limited | Construction | 1966 |
| Dental Pathway (Software) Limited | Information & communication | 2025 |
| Dermatology Clinic Community Service Ltd | Health & social care | 2011 |
| Design Your Life Ltd | Administrative & support | 2020 |
| Designs by US Limited | Construction | 2019 |
| Devi Enterprise Ltd | Wholesale & retail | 2014 |
| Dhamar Ltd | Other services | 2015 |
| Diamond Domestic Cleaning Ltd | Administrative & support | 2018 |
| Dianova Technologies Ltd | Manufacturing | 2025 |
| Dice Contracting Ltd | Construction | 2022 |
| Dickinson Operational Consulting Limited | Professional & scientific | 2026 |
| Dienstleistungszentrum Bayern Ltd | Administrative & support | 2021 |
| Digihiro Ltd | Wholesale & retail | 2020 |
| Dilmat Ltd | Other services | 2018 |
| Dimytek Ltd | Other services | 2023 |
| Direct Engineering (UK) Limited | Professional & scientific | 1994 |
| Disengaged Limited | Wholesale & retail | 2019 |
| Disobey Limited | Information & communication | 2018 |
| Divergent Life Ltd | Health & social care | 2023 |
| Diversey J Trustee Limited | Financial services | 2010 |
| DK Detailing & Valeting Ltd | Wholesale & retail | 2021 |
| DK Marine Services and Repair Limited | Manufacturing | 2023 |
| Dlgk Ltd | Real estate | 2025 |
| DMH Earthworks Solutions Ltd | Construction | 2024 |
| DMH Project Management Ltd | Professional & scientific | 2017 |
| DMS Original Ltd | Manufacturing | 2017 |
| DND Electrical Solutions Ltd | Construction | 2023 |
| DO IT Bodysense Ltd | Administrative & support | 2020 |
| Dogs Delight Ltd. | Administrative & support | 2020 |
| Dolphin Fairway Limited | Manufacturing | 1986 |
| Dolphin Packaging (Cheltenham) Limited | Manufacturing | 1963 |
| Dolphin Packaging (Holdings) Limited | Manufacturing | 1987 |
| Dolphin Packaging Limited | Manufacturing | 1975 |
| Domestic and Commercial Garden Services Ltd. | Administrative & support | 2003 |
| Domestic Garden Services Ltd. | Administrative & support | 2006 |
| Domino Business Consulting Limited | Professional & scientific | 2024 |
| Dorcas Engineering Limited | Manufacturing | 1971 |
| Dorfam Ltd | Other services | 2018 |
| Dotraks Ltd | Other services | 2018 |
| Double Yolk Consulting Limited | Professional & scientific | 2017 |
| Doves Hygiene Services Ltd | Water & waste | 2007 |
| DR Roberta RE Food Science Cambridge Ltd | Extraterritorial | 2024 |
| Draboks Ltd | Other services | 2018 |
| Dragonfly Medical Services Limited | Health & social care | 2017 |
| Dreidot Ltd | Health & social care | 2019 |
| Driftbitz Performance Garage Ltd. | Wholesale & retail | 2012 |
| Drott Ltd | Other services | 2022 |
| DSF Plumbing Services Ltd | Construction | 2025 |
| DSJ Bespoke Limited | Manufacturing | 2023 |
| DSJ Design Limited | Professional & scientific | 2025 |
| DSJ Facilities Limited | Administrative & support | 2025 |
| Dsphonics Ltd | Information & communication | 2022 |
| DTA Services Limited | Manufacturing | 2026 |
| Dts.Solutions (U.K) Ltd. | Administrative & support | 1988 |
| Duck END Developments Ltd | Construction | 2023 |
| Duck Lane Developments Limited | Real estate | 2008 |
| Dufaylite Group Limited | Manufacturing | 2000 |
| Durrant and Sons Limited | Real estate | 2019 |
| Durrant Garage Services Ltd | Wholesale & retail | 2018 |
| Duskwork Ltd | Manufacturing | 2021 |
| DXN Interiors Ltd | Manufacturing | 2025 |
| DXN Professional Tiling Ltd | Construction | 2021 |
| DXN Property Group Ltd | Real estate | 2021 |
| E.G.B. the England-Germany-Bridge Stiftungs-Foundation | Health & social care | 2023 |
| E.M.S Electro Medical Systems UK Limited | Manufacturing | 2018 |