| Stephanie Leonard Holdings Limited | Financial services | 2023 |
| Stephen Goddard Associates Limited | Professional & scientific | 2003 |
| Sterling AJO Savers International Community Club Limited | Professional & scientific | 2024 |
| Sterling Partitions ST Helens Ltd | Construction | 2014 |
| Stewart G Cross Ltd | Professional & scientific | 2011 |
| Sticky Cat Solutions Limited | Administrative & support | 2014 |
| Stix & Stems Ltd | Professional & scientific | 2021 |
| STK Construction Limited | Real estate | 1995 |
| Stockside Developments Limited | Real estate | 2013 |
| Stokespaint Ltd | Wholesale & retail | 2026 |
| Stone Arch Holdings Limited | Real estate | 2016 |
| Stone Design (NW) Ltd | Construction | 2024 |
| Stone Property Solutions Limited | Real estate | 2007 |
| Stone Tyres Limited | Wholesale & retail | 2016 |
| Stone Tyres MOT and Service Centre Ltd | Wholesale & retail | 2020 |
| Storage Tank Solutions Limited | Manufacturing | 2007 |
| Store My Stuff Ltd | Real estate | 2020 |
| Stott Properties Limited | Real estate | 2024 |
| Stow & Go Ltd | Administrative & support | 2026 |
| Strand Pharma Ltd | Wholesale & retail | 2025 |
| Straw Trader Limited | Transport & logistics | 2024 |
| Streamtech Services Limited | Information & communication | 2025 |
| Strong Tower Group Ltd | Construction | 2026 |
| Strongbox Self-Storage Ltd | Transport & logistics | 2013 |
| Stuart Milne Commercial Services Ltd | Professional & scientific | 2017 |
| Stuart Roberts Limited | Construction | 2014 |
| Student Consultancy Group Ltd | Wholesale & retail | 2022 |
| Studio Lateral Ltd | Information & communication | 2024 |
| Studio One Creative Ltd | Professional & scientific | 2020 |
| Studio Wood Interiors Ltd | Manufacturing | 2025 |
| Stumand Holdings Ltd | Financial services | 2025 |
| Summer 4UA Limited | Hospitality | 2022 |
| Summit Supplies Ltd | Wholesale & retail | 2024 |
| Sunlight Fusion Limited | Hospitality | 2019 |
| SUNLIGHT786 Limited | Hospitality | 2024 |
| Sunmate Ltd | Construction | 2025 |
| Sunny Steps Childcare Ltd | Health & social care | 2025 |
| Sunrize Health Care Recruitment Ltd | Administrative & support | 2022 |
| Sunstone Signal Ltd | Professional & scientific | 2026 |
| Supa News Limited | Wholesale & retail | 2022 |
| Super Ices Ltd | Hospitality | 2024 |
| Superior Wraps NW Ltd | Professional & scientific | 2023 |
| Supernova Power Holding Ltd | Financial services | 2025 |
| Supernova Power Ltd | Financial services | 2025 |
| Supersafety Limited | Wholesale & retail | 2015 |
| Sure Cyber Ltd | Information & communication | 2026 |
| Sure Steel Services Limited | Manufacturing | 2008 |
| Surefil Investments Limited | Financial services | 2008 |
| Surefire Building Ltd | Construction | 2022 |
| Surefire Partners Ltd | Professional & scientific | 2016 |
| Survivor Researcher Network C.I.C. | Health & social care | 2021 |
| Sutton Bargains Ltd | Wholesale & retail | 2025 |
| Sutton Cars Ltd | Wholesale & retail | 2003 |
| Sutton Leach Brick and Stonework Limited | Construction | 2026 |
| Sutton Pharmacy Limited | Wholesale & retail | 2002 |
| Sutton Pizza & Kebab Ltd | Hospitality | 2025 |
| SV POS Ltd | Manufacturing | 2025 |
| SW Electrical (UK) Limited | Construction | 2004 |
| Swadex Limited | Information & communication | 2024 |
| Swarm Business Communities Ltd | Administrative & support | 2026 |
| Sweet Treat Cosmetics Ltd | Wholesale & retail | 2025 |
| Sydney-Edward Engineering Limited | Construction | 2022 |
| Sylemotors Limited | Wholesale & retail | 2022 |
| Syncro CST Ltd | Administrative & support | 2019 |
| Syncro Fire & Security Limited | Administrative & support | 2007 |
| Syncro Group Limited | Administrative & support | 2017 |
| Systems and Security Ltd | Information & communication | 2007 |
| T & IK Plastic Surgery Ltd | Health & social care | 2010 |
| T & T Fast Solutions Limited | Transport & logistics | 2021 |
| T C Motion Repairs Ltd | Wholesale & retail | 2017 |
| T F Jones Property Services Limited | Construction | 2005 |
| T H Quick Transport Limited | Transport & logistics | 2013 |
| T R Property Investments (NW) Limited | Real estate | 2011 |
| T&K Consult Services Ltd | Wholesale & retail | 2025 |
| T&K Transport London Ltd | Extraterritorial | 2013 |
| T.F.E. Consultants Ltd | Other services | 2004 |
| T40 Renovations Ltd | Construction | 2025 |
| Tabeth Ltd | Health & social care | 2015 |
| Tacology Ltd | Hospitality | 2025 |
| TAG Merchandise Ltd | Arts & recreation | 2017 |
| Tailored Financial Planning Ltd | Financial services | 2015 |
| Talbot Road Healthcare Ltd | Wholesale & retail | 2024 |
| Talent Through Partnership Limited | Administrative & support | 2017 |
| Tamabro Ltd | Real estate | 2021 |
| Tankmec Engineering Ltd | Professional & scientific | 2018 |
| Tannys.Sthelens Ltd | Hospitality | 2025 |
| Tannysmart Ltd | Wholesale & retail | 2025 |
| Tanzana Agro UK Ltd | Wholesale & retail | 2026 |
| Tarsus Courier Ltd | Transport & logistics | 2026 |
| Tasklord Builders & Renovation Ltd | Construction | 2025 |
| TAT Holdings Ltd | Financial services | 2025 |
| Tatiana's Medical Services Limited | Health & social care | 2012 |
| Taurus Cranes & Hoists Ltd | Manufacturing | 2018 |
| Taurus Leisure Limited | Hospitality | 2025 |
| Taurus Technology Ltd | Information & communication | 2024 |
| Taylor Beck Consulting Limited | Administrative & support | 2025 |
| Taylor's Academy of Performing Arts Ltd | Arts & recreation | 2024 |
| Taylored Property North West Limited | Real estate | 2025 |
| TCB Electrical Ltd | Construction | 2022 |
| TCD Hill Solutions Ltd | Transport & logistics | 2018 |