| Rainford Carpet Tile Company Limited | Wholesale & retail | 1995 |
| Rainford Carpets Ltd | Wholesale & retail | 2002 |
| Rainford Dental Surgery Limited | Health & social care | 2010 |
| Rainford Financial Services Limited | Financial services | 2007 |
| Rainford Golf Club Limited | Arts & recreation | 2003 |
| Rainford Junction Festival Community Interest Company | Arts & recreation | 2025 |
| Rainford Motorcycles Ltd | Wholesale & retail | 2024 |
| Rainford Online Trading Ltd | Wholesale & retail | 2014 |
| Rainford Project Management Services Limited | Professional & scientific | 2017 |
| Rainford Properties Limited | Real estate | 2018 |
| Rainford Renewables Ltd | Energy | 2023 |
| Rainford Tennis Club CIC | Education | 2025 |
| Rainford Thunderbird Ltd | Wholesale & retail | 2024 |
| Rainford Vehicles Limited | Wholesale & retail | 2014 |
| Rainford X Sports and Social Club Community Interest Company | Hospitality | 2013 |
| Rainford's Farm Ltd | Agriculture & fishing | 2024 |
| Rainford's Picnic in the Park CIC | Arts & recreation | 2024 |
| RAJ Liverpool Ltd | Hospitality | 2026 |
| RAL Energy Limited | Construction | 2022 |
| Ralph a Rigby Insurance Services Limited | Financial services | 2004 |
| Ramzancopy Limited | Information & communication | 2026 |
| Ranx Ltd | Wholesale & retail | 2020 |
| Rapidin Express Ltd | Transport & logistics | 2026 |
| Raquel Monroy Nutrition Ltd | Health & social care | 2022 |
| RAR Rendering Ltd | Construction | 2022 |
| Rare Bags Limited | Financial services | 2024 |
| Ratcliffe Property Group Ltd | Real estate | 2026 |
| Ravic Solutions Ltd | Professional & scientific | 2024 |
| RAW Real Estate Limited | Real estate | 2023 |
| RAY GUY Consultancy Services Ltd | Construction | 2013 |
| RAY Installations Limited | Construction | 2021 |
| RBK Telecom Ltd | Information & communication | 2021 |
| RBM Systems Ltd | Professional & scientific | 2017 |
| RBQ Consultancy Ltd | Professional & scientific | 2015 |
| RC Extrem Cleaning Ltd | Administrative & support | 2025 |
| Rcarney Care Ltd | Health & social care | 2025 |
| RCB Property Maintenance Limited | Construction | 2025 |
| RDG Consultancy Ltd | Professional & scientific | 2026 |
| Re-Gen Mechanical Services Ltd | Construction | 2024 |
| Reagan Trading Ltd | Wholesale & retail | 2024 |
| Realm of Games Ltd | Wholesale & retail | 2026 |
| Reaz Barber Limited | Other services | 2022 |
| Rebecca Walsh Private Gyms Ltd | Arts & recreation | 2026 |
| Rebel Property Management Ltd | Real estate | 2024 |
| Reclaimed and Restored Limited | Construction | 2018 |
| Recycle Proline Ltd | Wholesale & retail | 2008 |
| Red FOX Facades Limited | Professional & scientific | 2024 |
| Red Robin Homecare Ltd | Health & social care | 2023 |
| Red Rose Technical Support Services Ltd | Wholesale & retail | 2023 |
| Red Sky Engineering Design Services Ltd | Professional & scientific | 2023 |
| Red Squirrel Storage Limited | Other services | 2014 |
| Redline NW Ltd | Transport & logistics | 2025 |
| Reds Real Estate Ltd | Real estate | 2024 |
| Reed Electrical Systems and Services Ltd | Construction | 2025 |
| Refuelgroup Ltd | Hospitality | 2024 |
| Refyx Limited | Wholesale & retail | 2025 |
| Regen Renovations Ltd | Construction | 2024 |
| Regency Joinery (North West) Limited | Construction | 2016 |
| Regenix Limited | Professional & scientific | 2024 |
| Reliable Resourcing Limited | Administrative & support | 2022 |
| Relish the Caterer Ltd | Hospitality | 2017 |
| Remark Buildings Limited | Real estate | 2013 |
| Renaissance Community Care Services Limited | Health & social care | 2016 |
| Rent-R-Us Ltd | Real estate | 2022 |
| Rental Network Ltd | Real estate | 2022 |
| Renten Limited | Professional & scientific | 2018 |
| Reolise Limited | Extraterritorial | 2022 |
| Resell Connect Ltd | Wholesale & retail | 2024 |
| Reservoir Dog Grooming and Pet Supplies Ltd | Wholesale & retail | 2020 |
| Resh Investment Properties Ltd | Real estate | 2025 |
| Resiliency Ltd | Public administration | 2025 |
| Resolveforge Ltd | Information & communication | 2025 |
| Resonance Integrated Energy Services Ltd | Professional & scientific | 2026 |
| Reverse Osmosis World Ltd | Wholesale & retail | 2023 |
| Revive Wellness CIC | Other services | 2025 |
| RF Commercial Services Limited | Administrative & support | 2017 |
| RG Inspection & Access Services Ltd | Professional & scientific | 2019 |
| RG Inspection Limited | Professional & scientific | 2025 |
| RGC Electrical Consultancy Ltd | Construction | 2017 |
| RHI ST Helens Ltd | Hospitality | 2020 |
| Rhumbline Consulting Limited | Education | 2017 |
| Ribbleton Healthcare Limited | Wholesale & retail | 2023 |
| Rich Girls Only Ltd | Professional & scientific | 2026 |
| Richard Moon Healthcare Limited | Wholesale & retail | 2023 |
| Richard’S Light CIC | Health & social care | 2025 |
| Riekstins Ltd | Information & communication | 2025 |
| Rigby Automotive Services Ltd | Transport & logistics | 2025 |
| Rigby Holdings Limited | Financial services | 2007 |
| Rigby Site Management Ltd | Professional & scientific | 2025 |
| Rigoto Group Ltd | Wholesale & retail | 2024 |
| RIO Pictures Limited | Information & communication | 2013 |
| Rithura Super Store Ltd | Wholesale & retail | 2025 |
| RJ Body Repairs Ltd | Wholesale & retail | 2020 |
| RJ Body Repairs North West Ltd | Wholesale & retail | 2024 |
| RJA Medical Ltd | Health & social care | 2022 |
| RJB Automotive Ltd | Wholesale & retail | 2021 |
| RK Carmen Ltd | Wholesale & retail | 2026 |
| RL Homes Ltd | Administrative & support | 2017 |
| RLK Takeout Ltd | Hospitality | 2025 |
| RLS Consultancy Services Ltd | Professional & scientific | 2023 |