| RV Moat House Management Ltd | Health & social care | 2013 |
| RW Electrical Services Ltd | Construction | 2025 |
| RW Engineering Lincs Limited | Professional & scientific | 2009 |
| RWD Transport Ltd | Transport & logistics | 2019 |
| RWS Home Improvements Ltd | Construction | 2025 |
| Ryecal Ltd. | Manufacturing | 2017 |
| S & J Associates Limited | Information & communication | 2013 |
| S & J Jenkinson Limited | Wholesale & retail | 2006 |
| S & S Developments Limited | Professional & scientific | 1990 |
| S & S Grounds Maintenance Limited | Administrative & support | 2026 |
| S & S Property Improvements (Yorkshire) Ltd | Construction | 2025 |
| S a Parker Construction Services Ltd | Construction | 2019 |
| S B S Welding Limited | Other services | 2016 |
| S Butler Interiors Limited | Construction | 2014 |
| S Cole Developments Ltd | Other services | 2016 |
| S E Warner & SON Ltd | Agriculture & fishing | 2015 |
| S G Baker Limited | Manufacturing | 1955 |
| S H & M B Properties Limited | Construction | 2017 |
| S Hughes Haulage Limited | Transport & logistics | 2025 |
| S J Cooke Farming Limited | Agriculture & fishing | 2024 |
| S J LEE Installations Ltd | Other services | 2013 |
| S K Cleaning Limited | Other services | 2009 |
| S Mounsey Flooring Ltd | Construction | 2022 |
| S P Forth Holdings Ltd | Financial services | 2024 |
| S P Suspension Limited | Professional & scientific | 2016 |
| S R Trucks Ltd | Transport & logistics | 2020 |
| S Ripley Surfacing Ltd | Construction | 2019 |
| S W Commercials (Midlands) Ltd | Wholesale & retail | 2025 |
| S W Jordan Painting and Decorating Ltd | Construction | 2019 |
| S&G Beaumont Ltd | Extraterritorial | 2018 |
| S&S Property Consultants Ltd | Professional & scientific | 2021 |
| S-Elec Limited | Manufacturing | 2008 |
| S-Guardian Ltd | Transport & logistics | 2019 |
| S. a. Electrical (Lincs) Limited | Construction | 2013 |
| S.A. Moore Transport Limited | Transport & logistics | 2003 |
| S.C. Trading Limited | Information & communication | 2006 |
| S.J. Bailey (Lincs) Ltd | Professional & scientific | 2012 |
| S.V. Cladding Ltd | Construction | 2021 |
| S.V. Venni and SON Limited | Transport & logistics | 1998 |
| S2 & Company Limited | Administrative & support | 2014 |
| S2 Industries Limited | Wholesale & retail | 2011 |
| SA Services (Lincs) Ltd | Transport & logistics | 2018 |
| Saas Growth Limited | Financial services | 2022 |
| Sabeen Ltd | Hospitality | 2022 |
| Sadiloff Limited | Transport & logistics | 2011 |
| Safe to Go Security Ltd | Administrative & support | 2026 |
| Safemed Supplies Limited | Extraterritorial | 2010 |
| Safezone Electrical Limited | Construction | 2014 |
| Saffron Take Away London Limited | Hospitality | 2024 |
| Sagat's Ltd | Wholesale & retail | 2025 |
| Saint Management Limited | Professional & scientific | 2022 |
| Sairen Ltd | Information & communication | 2026 |
| Saldat Ltd | Transport & logistics | 2023 |
| Sales Links Consultancy Ltd | Professional & scientific | 2016 |
| Salix Homes Limited | Construction | 2023 |
| Salon Alchemy Limited | Other services | 2019 |
| Salon Direct Holdings Ltd | Wholesale & retail | 2024 |
| Salon-A Spalding Ltd | Other services | 2023 |
| Salter & Sons Plant Hire Ltd | Administrative & support | 2025 |
| Salter Land Developments Ltd | Construction | 2025 |
| Salters Farriery Limited | Administrative & support | 2019 |
| Salters Landscaping and Property Maintenance Limited | Other services | 2013 |
| Salway and Wright (Spalding) Limited | Administrative & support | 2009 |
| Salway and Wright Limited | Professional & scientific | 1999 |
| SAM Marshall Art Limited | Arts & recreation | 2022 |
| Sam's Window Cleaning Ltd | Administrative & support | 2015 |
| Samba Soccer Schools Lincolnshire Ltd | Education | 2024 |
| Samez Ltd | Wholesale & retail | 2025 |
| Sammytrans Limited | Wholesale & retail | 2021 |
| Samuel Predii Ltd | Health & social care | 2019 |
| Sam’S Apex Personal Training Ltd | Arts & recreation | 2026 |
| Sanderdens Limited | Construction | 1987 |
| Sandford Mckay Investments Limited | Real estate | 2024 |
| Sandile Sizzla Possiwe Holdings Limited | Financial services | 2026 |
| Sandu Motors Ltd | Water & waste | 2016 |
| Sandutransport Ltd | Transport & logistics | 2015 |
| Sani Escapes Ltd | Administrative & support | 2024 |
| Sanpaul H&G Limited | Construction | 2018 |
| Sansbury Bailey Holdings Limited | Other services | 2001 |
| Santh Mariya Consultancy Ltd | Administrative & support | 2026 |
| Santi Boutique Limited | Wholesale & retail | 2021 |
| Saragasa Ltd | Health & social care | 2015 |
| Sarah Doina Ltd | Administrative & support | 2018 |
| SAS Letting Agents Ltd | Real estate | 2013 |
| Sasha Pallari Ltd | Arts & recreation | 2023 |
| Sasstainable Limited | Arts & recreation | 2019 |
| Satsumatastic Limited | Professional & scientific | 2009 |
| Saturn Walls & Ceilings Limited | Construction | 2018 |
| SAU7IUS Transport Ltd | Transport & logistics | 2024 |
| SAV Trips Ltd | Transport & logistics | 2022 |
| Savi Escapes Ltd | Administrative & support | 2025 |
| Savory Indulgence Limited | Hospitality | 2025 |
| Saxontech Ltd | Information & communication | 2024 |
| Saxton House Ltd | Health & social care | 2020 |
| SB Refrigeration and Electrical Engineers Ltd | Administrative & support | 2013 |
| SBS Leisure Ltd | Hospitality | 2025 |
| SC1 Networks Limited | Information & communication | 2015 |
| Scalasource Limited | Information & communication | 2019 |
| Scan IT Services Limited | Information & communication | 1998 |
| Scarlet Records Limited | Arts & recreation | 2009 |